Developmental Disorders Of The Frontostriatal System

In this book, the author discusses a range of common neurodevelopmental disorders affecting young people - autism, depression, schizophrenia, ADHD, Tourette's Syndrome and obsessive-compulsive disorder - from the unique perspective of their proposed common origin in the function and dysfunction of the brain's frontostriatal system. Throughout the book, the author systematically compares and contrasts them from a biological, clinical and evolutionary standpoint, viewing them as extensions of normal personality attributes, which, in less extreme form, may possess certain behavioural advantages, explaining their persistence in the general population. The result is a unique, up-to-date, and wide-ranging discussion of these disorders that draws upon biology, genetics, neuropsychology, neuropathology, neuroimaging, and clinical presentation and treatment. It will be of interest to advanced students, researchers and practitioners in neuropsychology, neuropsychiatry, psychiatry, and clinical psychology.

In this book, the author discusses a range of common neurodevelopmental disorders affecting young people - autism, depression, schizophrenia, ADHD, Tourette's Syndrome and obsessive-compulsive disorder - from the unique perspective of their proposed common origin in the function and dysfunction of the brain's frontostriatal system. Throughout the book, the author systematically compares and contrasts them from a biological, clinical and evolutionary standpoint, viewing them as extensions of normal personality attributes, which, in less extreme form, may possess certain behavioural advantages, explaining their persistence in the general population. The result is a unique, up-to-date, and wide-ranging discussion of these disorders that draws upon biology, genetics, neuropsychology, neuropathology, neuroimaging, and clinical presentation and treatment. It will be of interest to advanced students, researchers and practitioners in neuropsychology, neuropsychiatry, psychiatry, and clinical psychology.

Developmental Disorders of the Brain: Brain and Behaviour addresses disabilities that occur or have their roots in the early, developmental phase of life which are of utmost concern to parents, siblings, carers and teachers. This text describes the latest clinical and behavioral findings of disorders which largely or entirely involve the frontostriatal (basal ganglia) system including Tourette’s, Obsessive-Compulsive and Attention-Deficit-Hyperactivity disorders, Schizophrenia, Autism, gambling and addiction, depression, and Conduct, Developmental Motor Co-ordination, and language disorders. Examples of disorders involving the frontocerebellar are also described such as Asperger’s disorder, Williams, Fragile X, and Cerebellar Cognitive Affective syndromes, and Friedreich Ataxia. This book also discusses the relevant anatomy, physiology and pathology, and some of the major functions mediated by affected or relevant structures, together with accounts of the latest recording, brain imaging and stimulating techniques related to these kinds of disorders. Covering both frontostriatal and frontocerebellar, systems which control and direct normal behavior, and which can fail with often distressing consequences during development, as well as addressing behavioural, clinical, pathophysiological and technical aspects, this text is vital to understanding, diagnosis and management of developmental disorders of the brain. This text will be of great interest to clinicians, researchers, teachers and parents.

Developmental Disorders of the Brain: Brain and Behaviour addresses disabilities that occur or have their roots in the early, developmental phase of life which are of utmost concern to parents, siblings, carers and teachers. This text describes the latest clinical and behavioral findings of disorders which largely or entirely involve the frontostriatal (basal ganglia) system including Tourette’s, Obsessive-Compulsive and Attention-Deficit-Hyperactivity disorders, Schizophrenia, Autism, gambling and addiction, depression, and Conduct, Developmental Motor Co-ordination, and language disorders. Examples of disorders involving the frontocerebellar are also described such as Asperger’s disorder, Williams, Fragile X, and Cerebellar Cognitive Affective syndromes, and Friedreich Ataxia. This book also discusses the relevant anatomy, physiology and pathology, and some of the major functions mediated by affected or relevant structures, together with accounts of the latest recording, brain imaging and stimulating techniques related to these kinds of disorders. Covering both frontostriatal and frontocerebellar, systems which control and direct normal behavior, and which can fail with often distressing consequences during development, as well as addressing behavioural, clinical, pathophysiological and technical aspects, this text is vital to understanding, diagnosis and management of developmental disorders of the brain. This text will be of great interest to clinicians, researchers, teachers and parents.

Covering a wide range of diverse age-related disorders, Degenerative Disorders of the Brain addresses disabilities that occur or have their roots in the later stages of life. The book brings together an internationally recognised group of contributors to discuss frontostriatal, fronto-cerebellar and other major brain systems and structures which control and direct normal behaviour, and which can fail during the aging process, as well as addressing behavioural, clinical, pathophysiological and technical aspects. Discussing the latest clinical and behavioural findings of disorders which are largely, though not necessarily entirely, age related, including Alzheimer’s disease and other dementias, Parkinson’s disease and related disorders, and Huntington’s disease, the book covers information vital to the understanding, diagnosis, and management of degenerative disorders of the brain. It also considers the role of epigenetics, neural plasticity, and environmental enrichment in neurodegenerative disorders alongside the role of ground-breaking intervention methods, including transcranial magnetic stimulation and deep brain stimulation. Degenerative Disorders of the Brain will be of great interest to, and use for, clinicians, researchers, students, lecturers, and affected individuals and their relatives.

This brand-new text provides you with an easy-to-use, comprehensive reference that features a clinical perspective balanced with relevant basic science. Inside, you'll find discussions of the latest research and how it has led to a greater understanding of the cause of disease, as well as burgeoning tests and the latest therapeutic agents available. From Alzheimer's disease to vestibular system disorders, you'll find the practical guidance you need to diagnose effectively and provide an appropriate therapeutic approach for each individual case. Plus, a templated, four-color design offers you easy access to pertinent information Integrates basic science with clinical neurology to help you better understand neurologic diseases and provide the most accurate diagnosis and best treatment plan for each patient. Discusses the latest research results and offers new information on treatment options. Features the expertise of international authorities, providing a worldwide perspective. Uses a templated, four-color format that makes information accessible and easy to understand—particularly the basic science concepts.

International Encyclopedia of Public Health, Second Edition, Seven Volume Set is an authoritative and comprehensive guide to the major issues, challenges, methods, and approaches of global public health. Taking a multidisciplinary approach, this new edition combines complementary scientific fields of inquiry, linking biomedical research with the social and life sciences to address the three major themes of public health research, disease, health processes, and disciplines. This book helps readers solve real-world problems in global and local health through a multidisciplinary and comprehensive approach. Covering all dimensions of the field, from the details of specific diseases, to the organization of social insurance agencies, the articles included cover the fundamental research areas of health promotion, economics, and epidemiology, as well as specific diseases, such as cancer, cardiovascular diseases, diabetes, and reproductive health. Additional articles on the history of public health, global issues, research priorities, and health and human rights make this work an indispensable resource for students, health researchers, and practitioners alike. Provides the most comprehensive, high-level, internationally focused reference work available on public health Presents an invaluable resource for both researchers familiar with the field and non-experts requiring easy-to-find, relevant, global information and a greater understanding of the wider issues Contains interdisciplinary coverage across all aspects of public health Incorporates biomedical and health social science issues and perspectives Includes an international focus with contributions from global domain experts, providing a complete picture of public health issues

In this Special Issue, we focus on maternal docosahexaenoic acid, 22:6n-3 (DHA), and arachidonic acid, 20:4n-6 (ARA), on children’s neurodevelopment. During the last trimester of gestation and for the first 18 months after birth, both DHA and ARA are preferentially deposited within the cerebral cortex at a rapid rate. The mode of action of these two fatty acids and their derivatives at different structural–functional roles, and their levels in the signaling pathways of the brain have been continuously studied. These fatty acids are also involved in various brain developmental processes; however, their mechanistic cross talks are not yet clearly known. Recent data suggest that there may be a need for a balanced proportion of ARA and DHA in infant formula due to their complementary benefits. This review describes the importance of ARA in addition to DHA to support optimal brain development and growth in an infant, and functional roles in the brain.