Diagnostic Pathology Spleen

This book is designed to be the most comprehensive book on splenic pathology to date. It is an easy to use, overview of the lesions, both neoplastic and nonneoplastic, that arise in the spleen. Topics of focus include infectious diseases and lymphoproliferative disorders of the spleen. It analyzes each entity under the categories of definition, etiologies and pathogenesis, clinical presentations, treatment, prognosis, imaging, macroscopic features, microscopic features, cytopathology and ancillary studies, and differential diagnosis. This text would be an ideal tool for surgical pathologists, Hematopathologists, pathology residents, and medical students. FEATURES: · Features the classic benefits of all Amirsys® titles, including time-saving bulleted text, Key Facts in each chapter, stunning annotated images, and an extensive index · Includes both an extensive antibody index and molecular factors index · Amirsys eBook Advantage(tm), an online version of the print book with fully searchable text

This book provides a comprehensive and up-to-date overview of the pathologic features of common benign and malignant hematopoietic disorders in spleen and liver for practicing pathologists, hematopathologists and clinicians. The authors are from large academic centers, affiliated teaching hospitals and central referral clinics and are experienced in the diagnosis of hematopoietic disorders in the spleen and liver. The book consists of 21 chapters, with the first three chapters devoted to normal histologic features, conventional, cytogenetic and molecular studies necessary for the diagnosis of hematopoietic disorders in the spleen and liver. Chapters 4 to 17 cover the primary and secondary mature B- and T/NK cell lymphomas, Hodgkin lymphoma, B and T cell lymphoblastic leukemias, myeloid neoplasms, histiocytic and dendritic neoplasms, and post-transplant disorders including post transplant lymphoproliferative disorders. Chapters 19 to 21 encompass red blood cell disorders, other benign hematologic disorders and infectious/inflammatory disorders that could mimic hematopoietic neoplasms. These chapters are formatted on specific hematopoietic neoplasms to comprise epidemiology, etiology, pathogenesis, morphology, immunophenotyping, molecular genetics, prognosis and brief treatment guidelines. Diagnostic caveats are included in order to have a quick review of the key points in each chapter. Diagnostic Pathology of Hematopoietic Disorders of Spleen and Liver covers most, if not all of the benign and malignant hematopoietic disorders in the spleen and liver and serves as a practical and useful resource for general pathologists and hematopathologists.

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of splenic pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the 2nd edition of Diagnostic Pathology: Spleen is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource. Provides essential knowledge focused entirely on splenic pathology, including immunohistochemistry, flow cytometry, and molecular testing as they relate to splenic lesions and their differential diagnoses Presents up-to-date information on splenic injury and laceration grading and management, the findings of next-generation sequencing studies, and a range of molecularly defined genetic alterations of spleen neoplasms Features an Antibody Index and Molecular Factors Index to assist with identification and diagnosis Includes 14 new chapters covering topics such as autoimmune disease involving the spleen, spleen anatomy, splenic microcirculation, immune function of the spleen, spleen imaging, leukemic non-nodal mantle cell lymphoma, Tay-Sachs disease, normal T-cell subsets, and many others Includes approximately 2,000 high-quality clinical and histologic images, gross pathology images, radiologic images, and full-color illustrations to help practicing and in-training pathologists reach a confident diagnosis Includes updated criteria, terminology, and classifications from the 2017 World Health Organization Classification of Lymphoid Neoplasms Employs consistently templated chapters, bulleted content, key facts, and annotated images for quick, expert reference at the point of care

This book provides a comprehensive and up-to-date overview of the pathologic features of common benign and malignant hematopoietic disorders in spleen and liver for practicing pathologists, hematopathologists and clinicians. The authors are from large academic centers, affiliated teaching hospitals and central referral clinics and are experienced in the diagnosis of hematopoietic disorders in the spleen and liver. The book consists of 21 chapters, with the first three chapters devoted to normal histologic features, conventional, cytogenetic and molecular studies necessary for the diagnosis of hematopoietic disorders in the spleen and liver. Chapters 4 to 17 cover the primary and secondary mature B- and T/NK cell lymphomas, Hodgkin lymphoma, B and T cell lymphoblastic leukemias, myeloid neoplasms, histiocytic and dendritic neoplasms, and post-transplant disorders including post transplant lymphoproliferative disorders. Chapters 19 to 21 encompass red blood cell disorders, other benign hematologic disorders and infectious/inflammatory disorders that could mimic hematopoietic neoplasms. These chapters are formatted on specific hematopoietic neoplasms to comprise epidemiology, etiology, pathogenesis, morphology, immunophenotyping, molecular genetics, prognosis and brief treatment guidelines. Diagnostic caveats are included in order to have a quick review of the key points in each chapter. Diagnostic Pathology of Hematopoietic Disorders of Spleen and Liver covers most, if not all of the benign and malignant hematopoietic disorders in the spleen and liver and serves as a practical and useful resource for general pathologists and hematopathologists.

Designed as a practical and very comprehensive reference for the practicing pathologist, Diagnostic Pathology Lymph Nodes and Spleen with Extranodal Lymphomas is a highly anticipated title in the Diagnostic Pathology series offered by Amirsys. As readers have come to expect from Amirsys reference tools, Diagnostic Pathology: Lymph Nodes and Spleen with Extranodal Lymphomas is filled with superior medical images, including gross and microscopic pathology, a wide range of pathology stains, ancillary tests and detailed medical illustrations. For each anatomical site, you'll find specimen examination protocols plus detailed immunohistochemistry panels to accompany the images. This one-of-a-kind book covers a variety of benign and malignant disorders and lymphomas, such as infectious causes of lymphadenitis, reactive lymphadenopathies, immunodeficiency-associated lymphoproliferations, and granulocytic tumors of the lymph nodes, spleen and extranodal sites. Additionally, as with our other Diagnostic Pathology titles, chapters include definitions, terminology, etiologies and pathogenesis, demographics, clinical presentations, therapy, prognoses, radiologic imaging, pathology, and differential diagnoses. The pathologic features are extensively detailed with descriptions of macroscopic features, microscopic findings, cytopathology, and ancillary studies. The latter include histochemistry, immunohistochemistry, cytogenetics, molecular diagnostics and ultrastructural findings. This handsome volume will guide the reader through the intricacies of lymph node, spleen, and extranodal pathologies and the diagnosis of lymphomas and lymphadenopathies.

The spleen is an organ which has diverse functions including immunologic and hematologic. The Atlas of Spleen Pathology describes and selectively illustrates the normal and pathologic conditions that afflict the spleen. This extraordinary collection of high quality digital images will materially aid in continuing efforts to recognize, understand, and accurately interpret the gross and light microscopic findings in spleens.

The major aim of this book is to demystify splenic pathology for nonspecialist consultants and trainees in histopathology. The interpretation of pathological changes in the human spleen provides a significant challenge to the skills of even the most highly trained histopathologists. This comprehensive account of the most important and frequently encountered pathological conditions affecting the spleen is highly illustrated in color throughout with numerous detailed macroscopic and microscopic specimens. Emphasis is placed on the importance of adequate clinical information and technical preparation of splenectomy specimens in obtaining the best possible histopathological assessment of the tissue. A systematic, analytical approach to interpretation of pathological changes is used throughout the book. This text should enable readers to feel confident in their assessment of significant processes within the spleen. This volume will serve as an illustrated atlas, bench manual, text, and reference source.