Droplets Of Life

Droplets of Life: Membrane-Less Organelles, Biomolecular Condensates, and Biological Liquid–Liquid Phase Separation provides foundational information on the biophysics, biogenesis, structure, functions, and roles of membrane-less organelles. The study of liquid–liquid phase separation has attracted a lot of attention from disciplines such as cell biology, biophysics, biochemistry, and others trying to understand how, why, and what roles these condensates play in homeostasis and disease states in living organisms. This book's editor recruited a group of international experts to provide a current and authoritative overview of all aspects associated with this exciting area. Sections introduce membrane-less organelles (MLOs) and biomolecular condensates; MLOs in different sizes, shapes, and composition; and the formation of MLOs due to phase separation and how it can tune reactions, organize the intracellular environment, and provide a role in cellular fitness. . Presents the first book to establish the foundations of this exciting research area Combines biophysics, structural and cell biology, and biochemistry perspectives into a single volume Edited and authored by world-leading scientists Covers basic physical and biological principles and health and disease implications

Droplets of Life: Membrane-Less Organelles, Biomolecular Condensates, and Biological Liquid-Liquid Phase Separation provides foundational information on the biophysics, biogenesis, structure, functions and roles of membrane-less organelles. The study of Liquid-Liquid Phase Separation has attracted a lot of attention from disciplines such as Cell Biology, Biophysics, Biochemistry and others trying to understand how, why and what roles these condensates play in homeostasis and disease states in living organisms. This book's editor recruited a group of international experts to provide a current and authoritative overview of all aspects associated with this exciting area. Sections introduce MLOs and Biomolecular Condensates, MLOs in different sizes, shapes and composition and the formation of MLOs due to phase separation and how it can tune reactions, organize the intracellular environment, and provide a role in cellular fitness. Presents the first book to establish the foundations of this exciting research area Combines Biophysics, Structural and Cell Biology, and Biochemistry perspectives into a single volume Edited and authored by world-leading scientists Covers basic Physical and Biological principles and health and disease implications

"Make them go away!" This was the immediate reaction of young Mavis Pittilla when people from the spirit world began appearing unexpectedly in her home. One of these "spirit people" delivered a message that would ultimately save her life. Still, she wanted nothing to do with these visitors and sought help from her local Spiritualist church. There she learned to embrace these new experiences, opening her to a lifetime of service that has spanned continents. World-renowned and universally respected and beloved as a medium and teacher for over fifty years, Mavis Pittilla remains modest and humble. The story of her life reveals a multi-faceted, endearing woman who has overcome tremendous adversity, much of it caused by her own human frailties. Droplets of God is far more than Mavis's fascinating biography. It is a primer of the foundations of mediumship, the key philosophical teachings of Spiritualism, and of the soul's journey of self-realization.

Conflicting Models for the Origin of Life Conflicting Models for the Origin of Life provides a forum to compare and contrast the many hypotheses that have been put forward to explain the origin of life. There is a revolution brewing in the field of Origin of Life: in the process of trying to figure out how Life started, many researchers believe there is an impending second creation of life, not necessarily biological. Up-to-date understanding is needed to prepare us for the technological, and societal changes it would bring. Schrodinger’s 1944 “What is life?” included the insight of an information carrier, which inspired the discovery of the structure of DNA. In “Conflicting Models of the Origin of Life” a selection of the world’s experts are brought together to cover different aspects of the research: from progress towards synthetic life – artificial cells and sub-cellular components, to new definitions of life and the unexpected places life could (have) emerge(d). Chapters also cover fundamental questions of how memory could emerge from memoryless processes, and how we can tell if a molecule may have emerged from life. Similarly, cutting-edge research discusses plausible reactions for the emergence of life both on Earth and on exoplanets. Additional perspectives from geologists, philosophers and even roboticists thinking about the origin of life round out this volume. The text is a state-of-the-art snapshot of the latest developments on the emergence of life, to be used both in graduate classes and by citizen scientists. Audience Researchers in any area of astrobiology, as well as others interested in the origins of life, will find a modern and current review of the field and the current debates and obstacles. This book will clearly illustrate the current state-of-the-art and engage the imagination and creativity of experts across many disciplines.

This book constitutes the proceedings of the 15th Italian Workshop on Artificial Life and Evolutionary Computation, WIVACE 2021, held in Winterthur, Switzerland, in September 2022. The 14 full papers and 10 short papers presented in this volume were carefully reviewed and selected from 25 submissions. The papers are organized in the following topical sections: Networks; Droplets, Fluids, and Synthetic Biology; Robot Systems; Computer Vision and Computational Creativity; Semantic Search; Artificial Medicine and Pharmacy; Trade and Finance; Ethics in Computational Modelling. Chapters 4, 5, 6, 7, 22, and 24 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

One of the leading textbooks in its field, Bringing Fossils to Life applies paleobiological principles to the fossil record while detailing the evolutionary history of major plant and animal phyla. It incorporates current research from biology, ecology, and population genetics, bridging the gap between purely theoretical paleobiological textbooks and those that describe only invertebrate paleobiology and that emphasize cataloguing live organisms instead of dead objects. For this third edition Donald R. Prothero has revised the art and research throughout, expanding the coverage of invertebrates and adding a discussion of new methodologies and a chapter on the origin and early evolution of life.

Historical Introduction: A.I. Oparin and the Origin of Life.- Chapters in Honor of "Proiskhozhdenie Zhizni" and A. I, Oparin.- Protein Structure and the Molecular Evolution of Biological Energy Conversion.- Condensation Reactions of Lysine in the Presence of Polyadenylic Acid.- Considerations of the Origin of Spontaneous Mutations.- Pre-Enzymic Emergence of Biochemical Metabolism.- The Methods of Science and the Origins of Life.- Phospholipid Monolayers-As a Prototype of Biological Membranes.- Peptides and Amino Acids in the Primordial Hydrosphere.- Amino Acids and Carbohydrates in Precambria.

This book constitutes the revised selected papers of the 12th Italian Workshop on Advances in Artificial Life, Evolutionary Computation, WIVACE 2017, held in Venice, Italy, in September 2017.The 23 full papers presented were thoroughly reviewed and selected from 33 submissions. They cover the following topics: physical-chemical phenomena; biological systems; economy and society; complexity; optimization.