Endocrinology Neuroendocrinology Neuropeptides

Advances in Physiological Sciences, Volume 14: Endocrinology, Neuroendocrinology, Neuropeptides, Part II focuses on the research on neuropeptides, endocrinology, and neuroendocrinology. Composed of various contributions of able researchers, the first part of the book is divided into eight chapters. These chapters cover studies on the physiology, biochemistry, and localization of suspected hypothalamic releasing and inhibiting hormones. Researchers show how hormones react in different controlled environments. The second part of the selection deals with the use of in vitro systems in studying neuroendocrine regulation and steroid hormone action. This part is composed of four chapters wherein the extensive discussion of the processes involved is supported by experiments conducted on animals. The third part of the book covers the use of neurotransmitters in the control of anterior pituitary function. Composed of nine chapters, this part offers a thorough investigation of how neurotransmitters function in different controlled conditions. The fourth part of the selection, which is comprised of eight chapters, focuses on the function of neuropeptides as neurotransmitters. Studies are presented to elaborate the processes how neuropeptides can be converted to act as neurotransmitters. The last part, which covers nine chapters, deals exclusively with research on the effects of endogenous opioid peptides on the neuroendocrine system. The book is a great find for those interested in biochemistry.

Advances in Physiological Sciences, Volume 13: Endocrinology, Neuroendocrinology, Neuropeptides, Part I offers a lengthy discussion of the research, experiments, and investigations on endocrinology, neuroendocrinology, and neuropeptides. This selection, divided into five parts with 47 chapters, features the literature of able scholars who diligently conducted research on the subjects. The areas covered in their literature include discussions on hormone receptors and decoding of genetic information; biosynthesis, processing, and characterization of prehormones, prohormones, and hormones; pituit ...

This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.

The human genome encompasses ˜ 860 G protein-coupled receptors (GPCRs) including 374 non-chemosensory GPCRs. Half of these latter GPCRs recognize (neuro)peptides as natural ligands. GPCRs thus play a pivotal role in neuroendocrine communication. In particular, GPCRs are involved in the neuroendocrine control of feeding behavior, reproduction, growth, hydromineral homeostasis and stress response. GPCRs are also major drug targets and hence possess a strong potential for the development of innovative pharmaceuticals. The aim of this Research Topic was to assemble a series of review articles and original research papers on neuropeptide GPCRs and their ligands that would illustrate the different facets of the studies currently conducted in this domain.

70 years after the discovery of secretory neurons, internationally leading experts gathered to discuss the latest developments in neuropeptide research and endocrinology, concentrating on the molecular, cellular, supracellular and systemic aspects. A variety of neuropeptidergic systems are considered under comparative and evolutionary aspects.