Evolution S Wedge

Despite Darwin's emphasis, competition's role in diversification remains controversial and largely underappreciated.

In this explosive investigation into the limits of endurance, journalist and New York Times bestselling author Scott Carney discovers how humans can wedge control over automatic physiological responses into the breaking point between stress and biology. We can reclaim our evolutionary destiny.

Cancer cells exist in an ever-changing “ecology” and are subject to evolutionary pressures just like any species in nature. This edited book explores the following themes: 1) how the dynamics of mutation, epigenetics, and gene expression noise are sources of genetic diversity; 2) how scarce resources influence cancer therapy resistance; 3) how predator-prey dynamics are mirrored in immune-cancer cross-talk; 4) how cancer cells parallel niche construction theory; 5) how changing fitness landscapes enable cancer growth; and 6) how cancer cells interact within the body. The book is a resource for understanding cancer as a disease of multicellularity grounded in evolutionary principles. By using this knowledge, researchers are starting to exploit these behaviors for treatment paradigms. Key Features Bridges disciplines exemplifying the ways disparate fields create new perspectives when integrated. Offers insights from leading scholars in cancer biology, ecology and evolutionary biology. Provides a timely recognition by oncologists that evolutionary paradigms are crucial for breakthroughs in cancer treatment. Integrates basic and applied sciences of oncology and evolutionary biology.

Treatise on Geophysics: Crust and Lithosphere Dynamics, Volume 6, provides a comprehensive review of the state of knowledge on crust and lithosphere dynamics, which is defined as the study of how the outermost layers of the Earth respond to loads that are emplaced on, within, and below it and its implications for plate mechanics and mantle flow. The book begins with a chapter on plate kinematics, which shows how new observations and methodologies have improved the resolution of relative and absolute plate motions. This is followed by studies of plate mechanics, focusing on the long-term rheology of the plates and response of the plates to both relatively short-term and long-term loads. The book also includes chapters that examine the evidence from surface heat flow, borehole breakouts, and magma models for the thermal and mechanical structure of the lithosphere; the deformation of the lithosphere in extensional and compressional settings. The final two chapters deal with the structural styles of faulting in the shallow brittle part of the lithosphere, the brittle-ductile transition, and the shear zone in the ductile part of the lithosphere; and how developments in plate mechanics have impacted our understanding of geological processes. Self-contained volume starts with an overview of the subject then explores each topic with in depth detail Extensive reference lists and cross references with other volumes to facilitate further research Full-color figures and tables support the text and aid in understanding Content suited for both the expert and non-expert

This volume presents a collection of twenty-five peer-reviewed articles carefully selected from the contributions presented at the XXV Congress of the Portuguese Statistical Society (2021). Containing state-of-the-art developments in theoretical and applied statistics, the book will be accessible to readers with a background in mathematics and statistics, but will also be of interest to researchers from other scientific disciplines (e.g., biology, economics, medicine), who will find a broad range of relevant applications.

This book is dedicated to the great scientist and outstanding individual Nikolay Wladimirovich Timofeeff-Ressovsky. The book brings together a number of brief stories/essays about Timofeeff-Ressovsky including “Stories told by himself”, and scientific chapters addressing his major research areas: genetics, radiobiology, radiation ecology and epidemiology, and evolution. Timofeeff-Ressovsky contributed to several fields of biology and established new directions of scientific research. He often repeated the phrase, which would later become famous: “Science should not be approached with the ferocity of wild animals”. In keeping with that philosophy, the issues discussed here are still open. Each scientific part starts with a current review; the chapters present leading scientific schools and views. The main theme discussed in the genetics part is mutation variability in the context of linear (replication, transcription, translation) and conformational template processes, and its dependence on phylogenetic group. In turn, the radiobiology chapters focus on the reorganization of DNA, cell, and population variability under low-dose irradiation, sparking indirect processes and adaptive response. The radiation ecology and epidemiology parts present data on the consequences of nuclear plants and related accidents for ecological systems and human beings. Here some approaches to estimating radiation risks are also offered. Evolution laws are demonstrated in the genomic universe, plant-microbe symbiosis, stabilizing and destabilizing (directional) selection. The last essay demonstrates the principles of organization operating in local animal populations, which are approached as social organisms of complex systemic nature. The chapter 'Radiation-Induced Aging and Genetic Instability of Mesenchymal Stem Cells: An Issue for Late Health Effects?' is available open access under a CC BY 4.0 license.

Structural geology has developed at a very rapid pace in recent years. Evolution of Geological Structures in Micro- to Macro-Scales, covering a wide spectrum of current research in structural geology from the grain scale to the scale of orogenic belts and from the brittle to the ductile field, provides an overview of newly emerging concepts in a single volume. The book covers a wide range of advances in such broad fields as hydraulic factures, normal faults, overthrusts, ductile shear zones, rock fabrics, folds, superposed folds and basement structures.