Exscalate4cov

This book highlights the different aspects of the research project “E4C Horizon 2020 European Project” aimed at fighting the coronavirus by combining the best supercomputing resources and artificial intelligence with state-of-the-art experimental facilities up through clinical validation. Coronavirus disease has become an important public issue across the globe since December 2019. There is an urgent need to develop potent anti-COVID-19 agents for the prevention of the outbreak and stop viral infections. To this aim, a public–private consortium composed by European and national infrastructures, center of excellence, universities, and a pharmaceutical company started the E4C Horizon 2020 European Project: Its core idea was to use the EXaSCale smArt pLatform Against paThogEns (EXSCALATE) supercomputing platform for a process known as “drug repurposing”, namely to identify the most promising safe in man drugs for immediate treatment of the already infected population and then novel pan-coronavirus inhibitors to address future emergencies. This ambitious goal exploited a “chemical library” of 500 billion molecules, thanks to a processing capacity of more than 3 million molecules per second, made available by the computing power of the EXSCALATE platform.

This book constitutes the refereed post-conference proceedings of the First IFIP TC 5 International Conference on Computer Science Protecting Human Society Against Epidemics, ANTICOVID 2021, held virtually in June 2021. The 7 full and 4 short papers presented were carefully reviewed and selected from 20 submissions. The papers are concerned with a very large spectrum of problems, ranging from linguistics for automatic translation of medical terms, to a proposition for a worldwide system of fast reaction to emerging pandemic.

The Routledge Handbook of Europe–Korea Relations provides a comprehensive overview of the changing dynamics in relations between Europe and Korea, provided by leading experts in the field. Informed by high-quality academic research and key trilateral data and statistics, this book brings scope, balance, and depth, with wide-ranging coverage examining the history of Europe-Korea relations, the Cold War, contemporary Europe-Korea and Europe-North Korea relations, Europe and inter-Korea relations within the regional context, and relations between European countries and the Korea. Through this approach, it increases awareness of the extent and intensity of the multi-faceted and multi-layered connections between the Europe and Korea. Finally, it proposes a way forward for a future relationship between Europe and the Koreas. As a key reference point, for advanced-level students, researchers, policy-makers and journalists producing, and consuming, new material in the area and beyond, it provides an essential understanding of both the historical backdrop to, and the current crisis in, this troubled peninsula. This Handbook will be an essential reference for scholars, students, researchers and practitioners interested and working in the fields of Asian Politics/ Studies, EU Politics/Studies, European Politics/Studies, Korean Politics/Studies and International Relations. The Routledge Handbook of Europe–Korea Relations is part of the mini-series Europe in the World Handbooks examining EU-regional relations.

The current COVID-19 pandemic has infected more than 219 million people and killed more than 4.5 million people worldwide. It has also impacted the socioeconomic status of affected countries and led to the fastest development of vaccines in history. Over seven sections and seventeen chapters, this book comprehensively reviews numerous aspects of COVID-19, including epidemiology, zoonosis, drug development, telehealth, the effects of the virus on healthcare workers, the importance of architecture, and urbanism in preventing future pandemics, and much more.

In the dynamic environment of healthcare, the fusion of Computational Intelligence and Healthcare Industry 4.0 has enabled remarkable advancements in disease detection and analysis. However, a critical challenge persists – the limitations of current computational intelligence approaches in dealing with small sample sizes. This setback hampers the performance of these innovative models, hindering their potential impact on medical applications. As we stand at the crossroads of technological innovation and healthcare evolution, the need for a solution becomes paramount. Advances in Computational Intelligence for the Healthcare Industry 4.0 is a comprehensive guide addressing the very heart of this challenge. Designed for academics, researchers, healthcare professionals, and stakeholders in Healthcare Industry 4.0, this book serves as a source of innovation. It not only illuminates the complexities of computational intelligence in healthcare but also provides a roadmap for overcoming the limitations posed by small sample sizes. From fundamental principles to innovative concepts, this book offers a holistic perspective, shaping the future of healthcare through the lens of computational intelligence and Healthcare Industry 4.0.

This edited volume discusses the resilience of public-private partnerships (PPPs) in the wake of the COVID-19 pandemic. Using a comparative lens, the book assesses the degree to which global PPP infrastructure projects have been affected by the pandemic and details short term and long-term measures undertaken by governments and private parties to mitigate disruption to infrastructure delivery. Secondly, it focuses on improving the state-of-art knowledge by suggesting future directions to be taken by governments, practitioners, and researchers in order to create resilience in infrastructure projects when using PPPs as the delivery model. Chapters present diverse case studies of PPP governance across countries, covering topics such as regulatory issues, risk management, financing, contractual governance, arbitration, and stakeholder management. Providing a systematic review, assessment, and research agenda on lessons learned from the pandemic, this volume will appeal to researchers and students of public administration, public economics, construction management, infrastructure management, and public management, as well as practitioners and government professionals.

This essential book details intermediate-level statistical methods and frameworks for the clinician and medical researcher with an elementary grasp of health statistics and focuses on selecting the appropriate statistical method for many scenarios. Detailed evaluation of various methodologies familiarizes readers with the available techniques and equips them with the tools to select the best from a range of options. The inclusion of a hypothetical case study between a clinician and statistician charting the conception of the research idea through to results dissemination enables the reader to understand how to apply the concepts covered into their day-to-day clinical practice. Applied Statistical Considerations for Clinical Researchers focuses on how clinicians can approach statistical issues when confronted with a medical research problem by considering the data structure, how this relates to their study's aims and any potential knock-on effects relating to the evidence required to make correct clinical decisions. It covers the application of intermediate-level techniques in health statistics making it an ideal resource for the clinician seeking an up-to-date resource on the topic.