Hereditary Gynecologic Cancer

Hereditary Gynecologic Cancer: Risk, Prevention and Management fills the need that exists for a book addressing highly relevant clinical issues associated with the new field of hereditary gynecologic cancers. Written with the clinician in mind, the authors will cover a broad range of topics, beginning with an overview discussing clinical relevance of hereditary ovarian and hereditary endometrial cancers. Succeeding sections will provide in-depth analyses of Hereditary Breast Ovarian Cancer Syndrome, Lynch Syndrome, and other syndromes with gynecologic cancer components, and genetic risk assessment. Hereditary Gynecologic Cancer: Risk, Prevention and Management: is the first clinically focused reference detailing gynecologic patient management issues of BRCA1 and BRCA2 mutation carriers includes a practical section on genetic risk assessment and genetic testing examines case studies to demonstrate management techniques and decision-making provides detailed discussion of ovarian cancer screening, prevention and risk reducing surgery

Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.

This brand-new reference provides multidisciplinary guidance on the biology, diagnosis, treatment, and supportive care of patients with cancers of the female reproductive tract. An international group of experts present sections on management controversies, complications of cancer treatment, surgical techniques, symptom management, and more.

For the past decade or so, research regarding women’s health has become a major source of concern among health professionals. Due to the vast amounts of research, it has been difficult to amass a comprehensive source describing the challenges of physicians in this area of medical treatment and care. The Handbook of Research on Oncological and Endoscopical Dilemmas in Modern Gynecological Clinical Practice is a pivotal reference source that provides vital research on the application of clinical practices in regards to the health of women and prevention of severe, life-threatening diseases. While highlighting topics such as mental health, women’s health, and preventative care, this publication provides an insight into critical dilemmas and issues in modern gynecologic oncology and endoscopy as well as the methods of daily clinical practice. This book is ideally designed for obstetricians, gynecologists, specialized physicians, medical professionals, academicians, researchers, and medical students.

Overcoming Drug Resistance in Gynecologic Cancers provides up-to-date information related to important gynecologic cancers and focuses on mechanisms of drug resistance, genetics, signaling, immunology, health disparities, nanotechnology, economic considerations and financial impacts. The book covers not only drug resistance but also important means to reverse resistance both in the laboratory and clinic. The book discusses topics such as lifestyle, nutrition and risk of gynecologic cancers, the financial impact of drug resistance, chemosensitizing agents and targeted therapies in cervical, endometrial and ovarian cancer, immunotherapy to overcome drug resistance, and genetic polymorphisms in gynecologic cancers. Additionally, it discusses ethnic and racial health disparity perspectives and future developments in chemosensitizing activities to reverse drug resistance in gynecologic cancers. It is a valuable resource for cancer researchers, oncologists, clinicians and other biomedical field members who are interested in new approaches to improve chemotherapy outcome in patients with gynecologic cancers. Provides a comprehensive resource with all the details needed for readers to understand and follow information Encompasses schematics, diagrams and flow charts in all chapters to help readers easily follow critical information Presents tables and figures especially developed to summarize the information with appropriate statistical rigor and to show details of clinical specimens such as pathological, radiological characteristics, and/or laboratory biomarkers

This issue of the Obstetrics and Gynecology Clinics provides an update in Gynecologic Oncology. Vulvar/Vaginal, cervical, uterine, and ovarian cancer are all covered, along with early detection and screening, and genetics and hereditary risk. There is also an article on trends in cancer care in North America, which discusses cancer care and cost and sustainability as well as practice evloution.

This highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease. It starts off by presenting the molecular mechanisms, genetic testing and counseling, and variants of unknown significance (VUS) to help readers understand the contemporary interpretation of the disease. Further chapters focus on the surveillance, diagnosis and treatment, including chemoprevention, risk reduction and drug development based on molecular mechanisms. It also includes a chapter on the latest findings from the HBOC database, ethical issues and the parp inhibitors, and discusses innovative thinking to manage and understand the disease. Hereditary Breast and Ovarian Cancer - Molecular Mechanism and Clinical Practice offers breast surgeons, medical oncologists, gynecological oncologists and genetic counselors a comprehensive overview of the disease. Providing insights into recent scientific findings and further avenues for investigation, it is also a thought-provoking and informative read for researchers and scholars.