Heterocyclic N Oxides

This book provides a comprehensive presentation of all aspects of heterocyclic N-oxides. Topics discussed include the preparation of these compounds by N-oxidation of heterocycles and simultaneous synthesis of the ring and formation of the N-oxide group; general spectroscopic characteristics and molecular structure; and reactions and recently devel

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.

Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area-one of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties. Provides up-to-date material on a fast-growing and highly topical subject area Contains the latest research covering a wide variety of heterocyclic topics Written by leading authorities and designed as a handbook for students and industry and academic researchers

Provides a one-volume overall picture of the largest of the classical divisions of organic chemistry, suitable for the graduate or advanced undergraduate student, as well as for research workers, both specialists in the field and those engaged in another discipline and requiring knowledge of heterocyclic chemistry. It represents Volume 9 of Comprehensive Heterocyclic Chemistry and utilizes the general chapters which appear in the 8-volume work. The highly systematic coverage given to the subject makes this the most authoritative one-volume account of modern heterocyclic chemistry available.

This expanded second edition provides a concise overview of the main principles and reactions of heterocyclic chemistry for undergraduate students studying chemistry and related courses. Using a successful and student-friendly "at a glance" approach, this book helps the student grasp the essence of heterocyclic chemistry, ensuring that they can confidently use that knowledge when required. The chapters are thoroughly revised and updated with references to books and reviews; extra examples and student exercises with answers online; and color diagrams that emphasize exactly what is happening in the reaction chemistry depicted.

1. Structures and main physical properties of aromatic heterocycles 1; 2. Reactivity of aromatic heterocycles 18; 3. synthesis of aromatic heterocycles 56; 4. Typical reactivity of pyridines, quinolines, and isoquinolines 64; 5. Pyridines: reactions and synthesis 72; 6. Quinolines and isoquinolines: reactions and synthesis 120; 7. Typical reactivity of pyrylium and benzopyrylium ions, pyrones and benzopyrones 146; 8. Pyryliums, 2- and 4-pyrones: reactions and synthesis 148; 9. Benzopyryliums and benzopyrones: reactions and synthesis 166; 10. Typical reactivity of the diazines: pyridazine, pyrimidine and pyrazine 185; 11. the diazines: pyridazine, pyrimidine and pyrazine: reactions and synthesis 189; 12. Typical reactivity of pyrroles, thiophenes and furans 225; 13. Pyrroles: reactions and synthesis 229; 14. Thiophenes: reactions and synthesis 259; 15. Furans: reactions and synthesis 278; 16. Reactivity of indoles, benzo[b]thiophenes, benzo[b]furans, isoindoles, benzo[c]thiophenes and isobenzofurans 301; 17. Indoles: reactions and synthesis 305; 18. Benzo[b]thiophenes and benzo[b]furans: reactions and synthesis 350; 19. Isoindoles, benzo[c]thiophenes and isobenzofurans: reactions and synthesis 360; 20. Typical reactivity of 1,3- and 1,2-azoles 367; 21. 1,3-Azoles: imidazoles, thiazoles, and oxazoles: reactions and synthesis 370; 22. 1,2-Azoles: pyrazoles, isothiazoles and isoxazoles: reactions and synthesis 394; 23. Purines: reactions and synthesis 409; 24. Heterocycles containing a ring-junction nitrogen 434; 25. Heterocycles containing more than two hetero atoms 447; 26. Saturated and partially unsaturated heterocyclic compounds: reactions and synthesis 463; 27. Appendix: answers to exercises 479.