Intestinal Failure

This is the second and fully updated edition of the successful volume on intestinal failure in adults and children. The book provides a comprehensive coverage of all aspects of intestinal failure: from acute and chronic intestinal failure management and treatment, to outcomes, consequences and problems of treatment. In addition, 20 new chapters have been added, covering acute and chronic pancreatitis, critical care and abdominal pain among other topics. Each of the chapters contains a section with top tips on the topic, summarizing the essential take-home messages. Highly educational, this book is a must have for gastroenterologists but is of use for all members of a hospital nutrition support team including nurses, dietitians and pharmacists, whom it will serve as a practical guide for management of intestinal failure both in the hospital and in an outpatient setting. Written by a multidisciplinary author team, this book brings this important subject to a wide readership. With extensive referencing the book provides a detailed overview of the topic, discussing the latest research in the subject and how this relates to current clinical practice and potential future treatments.

Intestinal failure is a challenging, emerging field that has beenthe subject of much research and debate in recent years and hasonly recently become widely accepted as a distinct clinicalsyndrome. This comprehensive book provides an in-depth review ofscientific theory and clinical practice relating to intestinalfailure with specific emphasis on assessment and management as partof a multidisciplinary team. Compiled by an internationallyrecognised editorial team, the book provides a practical how-toguide to the management of adult and pediatric patients withintestinal failure, focusing on quality-of-life issues that are atthe heart of patient care. World experts from centers of excellence share their clinicalexperience and expertise, offering the first ever authoritativeresource on intestinal failure All aspects of patient management are covered, from diagnosisand medical and surgical management (including transplantation) tonutritional consideration and psychosocial aspects of care Numerous illustrations, flow diagrams and summary boxescomplement the text and emphasize important concepts, providing anaccessible approach to this complex field This landmark book is essential reading for anygastroenterologists, surgeons, transplant teams or clinicalnutritionists involved in the care of patients with intestinalfailure.

A complex disease entity, intestinal failure (IF) has only recently become accepted as a distinct clinical syndrome. Improvements across a wide range of disciplines—including critical care and organ transplantation as well as surgical, medical, and nutritional therapies—have led to a steady rise in survival and quality of life for patients with IF. Taking a current, multidisciplinary approach to their care, Clinical Management of Intestinal Failure offers intensive discussion of medical and nutritional issues in adults and children with intestinal failure. It addresses all facets of IF, including epidemiology, clinical presentation, intestinal rehabilitation, and transplantation. Topics covered include: Etiology and epidemiology Pathophysiology and clinical assessment Medical and surgical management Prevention and treatment of complications Nursing management Emerging diagnostic and therapeutic methods Long-term care Reflecting the diverse nature of IF clinical care and research, this book is written by a group of expert clinician scientists that includes gastroenterologists, surgeons, nurses, pharmacists, dietitians, social workers, and patients. They show how a multidisciplinary approach to patient care is instrumental in achieving optimal patient outcomes through more efficient lines of communication, improved monitoring of medications and their effects, detailed evaluation of growth parameters, and facilitation of the creative process that can lead to research breakthroughs. Advancing the discipline of IF, this book summarizes the current state of the art of patient management as well as new developments in the science of tissue engineering, medical and surgical therapy, and transplantation.

Adult Short Bowel Syndrome: Nutritional, Medical, and Surgical Management serves as a practical guide to the medical, surgical and nutritional care of complex patients with Short Bowel Syndrome (SBS), providing information on SBS with the most up-to-date, evidence-based data available. Additionally, the book presents global perspectives and highlights emerging areas of research that are influencing the care of patients with SBS. Intended for nutritionists, dieticians, physicians (specifically, general practitioners, gastroenterologists, and surgeons), nurse practitioners, pharmacists, students and researchers, this book serves as a quick reference on the medical, surgical and nutritional care of complex patients with short bowel syndrome. Presents emerging areas of research related to Short Bowel Syndrome (gut microbiome, pre/probiotics), as well as current applications in clinical practice Compiles an overview, classification and complications of the Short Bowel Syndrome disease state Contains effective dietary concepts (including rationale and use of oral rehydration solutions) for managing malabsorption caused by Short Bowel Syndrome Includes medical and pharmaceutical management techniques to compliment nutrition interventions Discusses surgical options for consideration in patients with Short Bowel Syndrome Highlights international perspectives on treatment and care

This book provides readers with a succinct but comprehensive overview of current concepts relating to intestinal failure, including its treatment, with a particular focus on recent advancements. The opening chapters address basic aspects of intestinal failure, including etiology, clinical pathophysiology, physiology of intestinal adaptation, and intestinal microbiota. The complications of intestinal failure, such as bacterial overgrowth and intestinal failure-associated liver disease, are then discussed. A series of chapters specifically address important strategies in the nutritional, pharmacological, and surgical treatment of intestinal failure as well as the concept of intestinal rehabilitation. Finally, two significant emerging developments are considered: regenerative medicine and distraction enterogenesis. The authors are internationally recognized experts from Europe and North America who are ideally placed to describe current knowledge and progress in the field.

For this important and unique issue of Gastroenterology Clinics, Consulting Editor Dr. Alan Buchman decided to serve as co-Guest Editor with Dr. David Hackam to provide a “bench to bedside look at intestinal failure. Authors have contributed reviews on the status of the science behind artificial organs while emphasizing how to clinically prepare for intestinal failure. Articles are devoted to the following topics: Initial Evaluation and Care of the Patient with New Onset Intestinal Failure; Getting the Patient Ready for Home Parenteral Nutrition; Pediatric Intestinal Failure: Etiology and Management; Predictors of Intestinal Adaptation in Children; Management of the Patient with Chronic Intestinal Pseudo-obstruction and Intestinal Failure; Intestinal Growth and Adaptation Following Resection in Intestinal Failure; Fluid and Electrolyte Management and Prevention of Dehydration in Intestinal Failure; The Oley Foundation and Consumer Support Groups; Weaning from Parenteral Nutrition; Hepatobiliary Complications of Intestinal Failure; Non-Transplant Surgery in Intestinal Failure; Indications for Intestinal Transplantation in Intestinal Failure; Intestinal Regeneration and the Artificial Gut; Bench to Bedside Approaches for Engineered Intestine, Esophagus and Colon; and Fetal and Amniotic Stem Cells in Gut Engineering. Readers will come away with a true state-of-the-art look at how to manage intestinal failure.

Short Bowel Syndrome: Practical Approach to Management is the first reference exclusively about the issues experienced by patients with a short bowel. It covers all aspects of normal and abnormal physiology, the presenting features, and outcomes, including metabolic problems, gallstones, and renal stones. It discusses both medical and surgical treatments, including intestinal transplantation. The use of growth factors, which is likely in the future to become increasingly important in promoting intestinal structural adaptation, is extensively discussed. Special emphasis is given to the psychosocial aspects of the quality of life of patients, including support groups. Emphasis is also given to the importance of an experienced multidisciplinary team in caring for these patients. This book is particularly timely given the recent advances in the management of Short Bowel Syndrome, including the availability of pharmacologic agents to enhance intestinal absorption, refinements in parenteral nutrition, and surgical procedures designed to eliminate the need for parenteral nutrition support. The goal of this international, interdisciplinary book is to bring the subject of Short Bowel Syndrome to a wide audience. A wide range of specialists have contributed to this book to provide various viewpoints on the state-of-the-art care of those with this condition.

The introduction of parenteral nutrition support has given patients with short bowel syndrome the time they need to achieve maximal intestinal rehabilitation and has allowed these patients to survive. The pioneering work of Drs. Byrnes and Wilmore in the 1990s focused on novel techniques to enhance intestinal adaptation and absorption, including mo