Lithium A Doctor A Drug And A Breakthrough

The remarkable untold story of a miracle drug, the forgotten pioneer who discovered it, and the fight to bring lithium to the masses. The DNA double helix, penicillin, the X-ray, insulin—these are routinely cited as some of the most important medical discoveries of the twentieth century. And yet, the 1949 discovery of lithium as a cure for bipolar disorder is perhaps one of the most important—yet largely unsung—breakthroughs of the modern era. In Lithium, Walter Brown, a practicing psychiatrist and professor at Brown, reveals two unlikely success stories: that of John Cade, the physician whose discovery would come to save an untold number of lives and launch a pharmacological revolution, and that of a miraculous metal rescued from decades of stigmatization. From insulin comas and lobotomy to incarceration to exile, Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade’s “Lithium Salts in the Treatment of Psychotic Excitement” described, for the first time, lithium’s astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide. And yet, as Brown shows, it would be decades before lithium would overcome widespread stigmatization as a dangerous substance, and the resistance from the pharmaceutical industry, which had little incentive to promote a naturally occurring drug that could not be patented. With a vivid portrait of the story’s unlikely hero, John Cade, Brown also describes a devoted naturalist who, unlike many modern medical researchers, did not benefit from prestigious research training or big funding sources (Cade’s “laboratory” was the unused pantry of an isolated mental hospital). As Brown shows, however, these humble conditions were the secret to his historic success: Cade was free to follow his own restless curiosity, rather than answer to an external funding source. As Lithium makes tragically clear, medical research—at least in America—has transformed in such a way that serendipitous discoveries like Cade’s are unlikely to occur ever again. Recently described by the New York Times as the “Cinderella” of psychiatric drugs, lithium has saved countless of lives and billions of dollars in healthcare costs. In this revelatory biography of a drug and the man who fought for its discovery, Brown crafts a captivating picture of modern medical history—revealing just how close we came to passing over this extraordinary cure.

DISCOVER THE ADHD SOLUTION FOR YOUR CHILD Dr. James Greenblatt has seen thousands of children and adults struggling with the symptoms of ADHD – hyperactivity, inattentiveness, impulsiveness, and often irritability and combativeness. Rather than simply prescribing medication for their ADHD symptoms, he tailors remedies to his patients’ individual needs, detecting and treating the underlying causes of the disorder. Finally Focused provides proven natural and medical methods to easily treat problems such as nutritional deficiencies or excesses, dysbiosis (a microbial imbalance inside the body), sleeping difficulties, and food allergies, all of which surprisingly can cause or worsen the symptoms of ADHD. Using Dr. Greenblatt’s effective Plus-Minus Healing Plan, parents will first understand the reasons behind their child's symptoms, and then be able to eliminate them by addressing the child’s unique pattern of biological weakness. Adults with ADHD can do the same for themselves. And if conventional medication is still necessary, this integrative approach will minimize or even eliminate troublesome side effects. Using Dr. Greenblatt’s expert advice, millions of children and adults with ADHD finally will get the help they need to achieve true wellness.

More than 30 years ago, Ronald R. Fieve, MD, gained national recognition for his pioneering treatment of what was then known as “manic-depression.” Since then, he has focused on patients with mild bipolarity, also known as Bipolar II. With the right treatment, these patients can turn their illness into an asset. In this groundbreaking book, Dr. Fieve presents a highly successful program that allows Bipolar II patients to harness the creativity and energy of their hypomanic “highs” while minimizing the potentially devastating “lows” of depression. Now with a new foreword explaining the most up-to-date research on the bipolar spectrum, Bipolar Breakthrough includes: -six stay-well strategies for anyone suffering from Bipolar II -the latest information on cutting-edge medications with fewer side effects -a special section on the complications of a bipolar diagnosis for pregnant women, children, and the elderly With results supported by thousands of patient histories, Dr. Fieve’s Bipolar Breakthrough is a landmark work that will help the millions of Bipolar II sufferers live better lives.

A fascinating and highly accessible look at the surprising role serendipity has played in some of the most important medical discoveries in the twentieth century.

How do scientists design the medicine we use to improve our lives? It turns out that many are happy accidents or overlooked mixtures of carbon and hydrogen that go on to not only improve the lives of people the world over, but become million- and billion-dollar makers for pharmaceutical companies. In Making Medicine: Surprising Stories from the History of Drug Discovery, author Keith Veronese examines fifteen different molecules and their unlikely discovery –or in many cases, their second discovery –en route to becoming invaluable medications. From the famous story of Alexander Fleming’s discovery of penicillin, to lesser-known stories surrounding drugs like quinine (derived from the bark of the cinchona tree and responsible for saving the lives of millions in the fight against malaria), Veronese reveals the “how” and the “who” behind the pharmaceutical breakthroughs that continue to impact our world. With subjects including cancer-fighting therapies and over-the-counter pain relievers; hair regrowth creams and antidepressants; readers will no doubt have a personal connection to at least one molecule in this book. Like all discoveries made by mankind, the stories behind these breakthroughs and their introduction to the world are often messy, sometimes controversial, and always human. Take digoxin, which correctly prescribed can help heart efficiency, but in higher doses can prove fatal –a fact known all too well by Charles Cullen, a nurse who used digoxin to kill over forty patients. Making Medicine also details how modern pharmaceutical discovery works, including the monumental challenge and accomplishment of creating a COVID-19 vaccine. This fascinating book highlights the serendipitous nature of the discovery of these miracle molecules, along with how they do (or don't) interact with the human body to produce the desired result.

In a nation plagued with chronic diseases such as cancer, heart disease, and diabetes, a different predator is the single greatest reason for disability in the United States: mental disorders. Our fast-paced and frenetic lifestyle, coupled with a grossly polluted environment, has created the perfect breeding ground for mental instability. With the spread of brain disorders on the rise around the world, nutritional biochemistry and one of its stars, lithium, has stepped into the spotlight to offer proven methods to heal our bodies from the inside out. Historically linked to severe psychiatric illness, lithium as an agent of good health and well-being is often ignored and brushed aside. Known as the Cinderella drug, it is an essential mineral in our physical and psychological makeup. Lack of its presence in the body can result in poor brain development, psychiatric symptoms, and so on. When administered in small, controlled doses, lithium can significantly improve the lives of those suffering from mental disorders. Nutritional Lithium: A Cinderella Story illustrates the significance of this precious mineral not only as a nutrient vital to human development, but also as a nutritional component that can help millions of people worldwide.

A veteran research scientist who has spent decades establishing biochemical treatment protocols for patients with ADHD, Alzheimer's disease and various mental disorders challenges popular opinions about psychiatric drugs to make recommendations for drug-free nutrient therapies that normalize the brain without producing serious side effects. 15,000 first printing.