Loie S Disease

Leukodystrophy is a life-limiting neurological disorder that can affect both children and adults. In an illustrated story based on her conversations with her children after their sister, Cal, was diagnosed with leukodystrophy, Maria Kefalas delivers a simple and powerful explanation from a child’s point of view that explains the workings of the brain, what a diagnosis means, and how to face the challenge as a family. “This is a beautiful book that delivers a powerfully simple, no nonsense explanation of leukodystrophy ... it reminds us that every single child needs and responds to our love and kindness.” —Rebecca Brenner, former teacher

Targeted Treatment of the Rheumatic Diseases takes a patient management approach to treating adult and pediatric patients with rheumatic diseases. Michael H. Weisman, Michael Weinblatt, James S Louie, and Ronald Van Vollenhoven offer their unique insights into choosing the correct pharmacological and non-pharmacological therapies for your patients. Chapters cover the full breadth of rheumatic diseases, rheumatoid arthritis, lupus, connective tissue diseases, osteoporosis, regional pain disorders, and fibromyalgia. The full-color design presents detailed clinical photographs and treatment algorithms for visual guidance and easy reference. You’ll have all you need to provide your patients with the most effective treatment from this unique resource. Focuses on patient management instead of disease management so that you can tailor treatment plans according to each patient’s needs. Covers the treatment of pediatric patients as well as adults so that you can properly address the particular needs of any patient you see. Features the guidance and specific recommendations of experts from United States and Europe for a state-of-the-art approach to the variety of treatments currently in use. Displays the clinical manifestations of rheumatic diseases in full color, along with treatment algorithms for easy at-a-glance reference.

This is a new edition of the successful textbook providing updated, detailed information on clinical, epidemiologic, pathophysiologic and therapeutic aspects of common and rare forms of vasculitis. New chapters include pathology of vasculitis, autoantibodies, animal models of vasculitis and PET scanning. Separate sections are devoted to basic science, clinical manifestations commonly seen in vasculitis, imaging and perpcutaneous interventions, individual diseases and syndromes as well as conditions which can mimic vasculitis. Subsumed under clinical manifestations are chapters, some new, which deal with skin, oral ulcers, eyes, cardiopulmonary system, nervous system, the gastrointestinal track, kidney and digital ischemia and Raynaud's phenomenon. Other chapters address diagnostic approaches to adults and to children with suspected vasculitis, as well as assessment of disease activity and damage. Individual chapters are written by authorities from throughout the world.

Infectious diseases remain a major problem for physicians and other health professionals dealing with problems of the reproductive system. Accordingly, this two-volume comprehensive presentation of infectious diseases involving the male and female reproductive systems promises to be a major contribution in this field and to fill a much-needed vacuum. During the past three decades, the introduction of antimicrobial therapy has dramatically altered both the clinical presentation and the therapeutic approaches employed in dealing with the traditional infections of the repro ductive system. In addition, the changing demographics of infectious problems in the industrial countries and the developing world have been a source of concern. A good deal of important information on this topic is included in this series. In recent years, considerable attention has been given to the role of Myco plasma and Chlamydia in both male and female infertility and the problems related to genital herpes and human papilloma virus infections. Current clinical information is included on these infections as well as on newer aspects of diagnosis, such as the use of laparoscopy in the diagnosis and treatment of pelvic inflammatory disease. Also addressed is new information regarding the role of actinomycosis in pelvic infections; current problems such as toxic shock syndrome and acquired immune deficiency syndrome (AIDS) are reviewed as well. New concepts are included in these vohimes to complement the clinical information. The attachment of microbial organisms to sperm may help to explain access of these and other organisms to the upper female genital tract.