Machine And Deep Learning In Oncology Medical Physics And Radiology

This book, now in an extensively revised and updated second edition, provides a comprehensive overview of both machine learning and deep learning and their role in oncology, medical physics, and radiology. Readers will find thorough coverage of basic theory, methods, and demonstrative applications in these fields. An introductory section explains machine and deep learning, reviews learning methods, discusses performance evaluation, and examines software tools and data protection. Detailed individual sections are then devoted to the use of machine and deep learning for medical image analysis, treatment planning and delivery, and outcomes modeling and decision support. Resources for varying applications are provided in each chapter, and software code is embedded as appropriate for illustrative purposes. The book will be invaluable for students and residents in medical physics, radiology, and oncology and will also appeal to more experienced practitioners and researchers and members of applied machine learning communities.

​This book provides a complete overview of the role of machine learning in radiation oncology and medical physics, covering basic theory, methods, and a variety of applications in medical physics and radiotherapy. An introductory section explains machine learning, reviews supervised and unsupervised learning methods, discusses performance evaluation, and summarizes potential applications in radiation oncology. Detailed individual sections are then devoted to the use of machine learning in quality assurance; computer-aided detection, including treatment planning and contouring; image-guided radiotherapy; respiratory motion management; and treatment response modeling and outcome prediction. The book will be invaluable for students and residents in medical physics and radiation oncology and will also appeal to more experienced practitioners and researchers and members of applied machine learning communities.

This pioneering book explores how machine learning and other AI techniques impact millions of cancer patients who benefit from ionizing radiation. It features contributions from global researchers and clinicians, focusing on the clinical applications of machine learning for medical physics. AI and machine learning have attracted much recent attention and are being increasingly adopted in medicine, with many clinical components and commercial software including aspects of machine learning integration. General principles and important techniques in machine learning are introduced, followed by discussion of clinical applications, particularly in radiomics, outcome prediction, registration and segmentation, treatment planning, quality assurance, image processing, and clinical decision-making. Finally, a futuristic look at the role of AI in radiation oncology is provided. This book brings medical physicists and radiation oncologists up to date with the most novel applications of machine learning to medical physics. Practitioners will appreciate the insightful discussions and detailed descriptions in each chapter. Its emphasis on clinical applications reaches a wide audience within the medical physics profession.

This book provides a comprehensive introduction to current state-of-the-art auto-segmentation approaches used in radiation oncology for auto-delineation of organs-of-risk for thoracic radiation treatment planning. Containing the latest, cutting edge technologies and treatments, it explores deep-learning methods, multi-atlas-based methods, and model-based methods that are currently being developed for clinical radiation oncology applications. Each chapter focuses on a specific aspect of algorithm choices and discusses the impact of the different algorithm modules to the algorithm performance as well as the implementation issues for clinical use (including data curation challenges and auto-contour evaluations). This book is an ideal guide for radiation oncology centers looking to learn more about potential auto-segmentation tools for their clinic in addition to medical physicists commissioning auto-segmentation for clinical use. Features: Up-to-date with the latest technologies in the field Edited by leading authorities in the area, with chapter contributions from subject area specialists All approaches presented in this book are validated using a standard benchmark dataset established by the Thoracic Auto-segmentation Challenge held as an event of the 2017 Annual Meeting of American Association of Physicists in Medicine

Artificial Intelligence Medicine: Technical Basis and Clinical Applications presents a comprehensive overview of the field, ranging from its history and technical foundations, to specific clinical applications and finally to prospects. Artificial Intelligence (AI) is expanding across all domains at a breakneck speed. Medicine, with the availability of large multidimensional datasets, lends itself to strong potential advancement with the appropriate harnessing of AI. The integration of AI can occur throughout the continuum of medicine: from basic laboratory discovery to clinical application and healthcare delivery. Integrating AI within medicine has been met with both excitement and scepticism. By understanding how AI works, and developing an appreciation for both limitations and strengths, clinicians can harness its computational power to streamline workflow and improve patient care. It also provides the opportunity to improve upon research methodologies beyond what is currently available using traditional statistical approaches. On the other hand, computers scientists and data analysts can provide solutions, but often lack easy access to clinical insight that may help focus their efforts. This book provides vital background knowledge to help bring these two groups together, and to engage in more streamlined dialogue to yield productive collaborative solutions in the field of medicine. Provides history and overview of artificial intelligence, as narrated by pioneers in the field Discusses broad and deep background and updates on recent advances in both medicine and artificial intelligence that enabled the application of artificial intelligence Addresses the ever-expanding application of this novel technology and discusses some of the unique challenges associated with such an approach

Machine Learning and Artificial Intelligence in Radiation Oncology: A Guide for Clinicians is designed for the application of practical concepts in machine learning to clinical radiation oncology. It addresses the existing void in a resource to educate practicing clinicians about how machine learning can be used to improve clinical and patient-centered outcomes. This book is divided into three sections: the first addresses fundamental concepts of machine learning and radiation oncology, detailing techniques applied in genomics; the second section discusses translational opportunities, such as in radiogenomics and autosegmentation; and the final section encompasses current clinical applications in clinical decision making, how to integrate AI into workflow, use cases, and cross-collaborations with industry. The book is a valuable resource for oncologists, radiologists and several members of biomedical field who need to learn more about machine learning as a support for radiation oncology. Presents content written by practicing clinicians and research scientists, allowing a healthy mix of both new clinical ideas as well as perspectives on how to translate research findings into the clinic Provides perspectives from artificial intelligence (AI) industry researchers to discuss novel theoretical approaches and possibilities on academic collaborations Brings diverse points-of-view from an international group of experts to provide more balanced viewpoints on a complex topic

The clinical use of Artificial Intelligence (AI) in radiation oncology is in its infancy. However, it is certain that AI is capable of making radiation oncology more precise and personalized with improved outcomes. Radiation oncology deploys an array of state-of-the-art technologies for imaging, treatment, planning, simulation, targeting, and quality assurance while managing the massive amount of data involving therapists, dosimetrists, physicists, nurses, technologists, and managers. AI consists of many powerful tools which can process a huge amount of inter-related data to improve accuracy, productivity, and automation in complex operations such as radiation oncology.This book offers an array of AI scientific concepts, and AI technology tools with selected examples of current applications to serve as a one-stop AI resource for the radiation oncology community. The clinical adoption, beyond research, will require ethical considerations and a framework for an overall assessment of AI as a set of powerful tools.30 renowned experts contributed to sixteen chapters organized into six sections: Define the Future, Strategy, AI Tools, AI Applications, and Assessment and Outcomes. The future is defined from a clinical and a technical perspective and the strategy discusses lessons learned from radiology experience in AI and the role of open access data to enhance the performance of AI tools. The AI tools include radiomics, segmentation, knowledge representation, and natural language processing. The AI applications discuss knowledge-based treatment planning and automation, AI-based treatment planning, prediction of radiotherapy toxicity, radiomics in cancer prognostication and treatment response, and the use of AI for mitigation of error propagation. The sixth section elucidates two critical issues in the clinical adoption: ethical issues and the evaluation of AI as a transformative technology.