Mems And Microfluidics In Healthcare

The book introduces the research significance of biomedical instrumentation and discusses micro-fabrication techniques utilized for biomedical devices. This book primarily focuses on the reader enlightenment on MEMS medical devices by introducing all the diagnostic devices and treatment tools at one place. The book covers in-depth technical works and general introductions to the devices such that the book can reach technical as well as non-technical readers.

"Advances in MEMS and Microfluidic Systems explores the emerging research and advances in MEMS device and microfluidic systems applications. It features in-depth chapters on microfluidic device design and fabrication as well as on the aspects of devices/systems, characterization, and comparative research findings. Covering topics such as biosensors, lab-on-a-chip, and microfluidic technology, this premier reference source is an indispensable resource for engineers, health professionals, students and educators of higher education, librarians, researchers, and academicians"--

Technological advancements in the last few decades have significantly revolutionized the healthcare industry, resulting in life expectancy improvement in human beings. The use of automated machines in healthcare has reduced human errors and has notably improved disease diagnosis efficiency. Design and Development of Affordable Healthcare Technologies provides emerging research on biomedical instrumentation, bio-signal processing, and device development within the healthcare industry. This book provides insight into various subjects including patient monitoring, medical imaging, and disease classification. This book is a vital reference source for medical professionals, biomedical engineers, scientists, researchers, and medical students interested in the comprehensive research on the advancements in healthcare technologies.

The application of Micro Electro Mechanical Systems (MEMS) in the biomedical field is leading to a new generation of medical devices. MEMS for biomedical applications reviews the wealth of recent research on fabrication technologies and applications of this exciting technology. The book is divided into four parts: Part one introduces the fundamentals of MEMS for biomedical applications, exploring the microfabrication of polymers and reviewing sensor and actuator mechanisms. Part two describes applications of MEMS for biomedical sensing and diagnostic applications. MEMS for in vivo sensing and electrical impedance spectroscopy are investigated, along with ultrasonic transducers, and lab-on-chip devices. MEMS for tissue engineering and clinical applications are the focus of part three, which considers cell culture and tissue scaffolding devices, BioMEMS for drug delivery and minimally invasive medical procedures. Finally, part four reviews emerging biomedical applications of MEMS, from implantable neuroprobes and ocular implants to cellular microinjection and hybrid MEMS. With its distinguished editors and international team of expert contributors, MEMS for biomedical applications provides an authoritative review for scientists and manufacturers involved in the design and development of medical devices as well as clinicians using this important technology. Reviews the wealth of recent research on fabrication technologies and applications of Micro Electro Mechanical Systems (MEMS) in the biomedical field Introduces the fundamentals of MEMS for biomedical applications, exploring the microfabrication of polymers and reviewing sensor and actuator mechanisms Considers MEMS for biomedical sensing and diagnostic applications, along with MEMS for in vivo sensing and electrical impedance spectroscopy

The Handbook of Silicon Based MEMS Materials and Technologies, Second Edition, is a comprehensive guide to MEMS materials, technologies, and manufacturing that examines the state-of-the-art with a particular emphasis on silicon as the most important starting material used in MEMS. The book explains the fundamentals, properties (mechanical, electrostatic, optical, etc.), materials selection, preparation, manufacturing, processing, system integration, measurement, and materials characterization techniques, sensors, and multi-scale modeling methods of MEMS structures, silicon crystals, and wafers, also covering micromachining technologies in MEMS and encapsulation of MEMS components. Furthermore, it provides vital packaging technologies and process knowledge for silicon direct bonding, anodic bonding, glass frit bonding, and related techniques, shows how to protect devices from the environment, and provides tactics to decrease package size for a dramatic reduction in costs. Provides vital packaging technologies and process knowledge for silicon direct bonding, anodic bonding, glass frit bonding, and related techniques Shows how to protect devices from the environment and decrease package size for a dramatic reduction in packaging costs Discusses properties, preparation, and growth of silicon crystals and wafers Explains the many properties (mechanical, electrostatic, optical, etc.), manufacturing, processing, measuring (including focused beam techniques), and multiscale modeling methods of MEMS structures Geared towards practical applications rather than theory

The field of microfluidics has in the last decade permeated many disciplines, from physics to biology and chemistry, and from bioengineering to medical research. One of the most important applications of lab-on-a-chip devices in medicine and related disciplines is disease diagnostics, which involves steps from biological sample/analyte loading to storage, detection, and analysis. The chapters collected in this book detail recent advances in these processes using microfluidic devices and systems. The reviews of portable devices for diagnostic purposes are likely to evoke interest and raise new research questions in interdisciplinary fields (e.g., efficient MEMS/microfluidic engineering driven by biological and medical applications). The variety of the selected topics (general relevance of microfluidics in medical and bioengineering research, fabrication, advances in on-chip sample detection and analysis, and specific disease models) ensures that each of them can be viewed in the larger context of microfluidic-mediated diagnostics. Contents:A Microscale Bioinspired Cochlear-like Sensor (Robert D White, Robert Littrell, and Karl Grosh)Systematic Evaluation of the Efficiencies of Proteins and Chemicals in Pharmaceutical Applications (Morgan Hamon and Jong Wook Hong)Microfluidic Glucose Sensors (Jithesh V Veetil, Sruthi Ravindranathan, Sha Jin, and Kaiming Ye)Applications of Microfabrication and Microfluidic Techniques in Mesenchymal Stem Cell Research (Abhijit Majumder, Jyotsna Dhawan, Oren Levy, and Jeffrey M Karp)Patient-Specific Modeling of Low-Density Lipoprotein Transport in Coronary Arteries (Ufuk Olgac)Point-of-Care Microdevices for Global Health Diagnostics of Infectious Diseases (Sau Yin Chin, Tassaneewan Laksanasopin, Curtis D Chin, and Samuel K Sia)Integrated Microfluidic Sample Preparation for Chip-based Molecular Diagnostics (Jane Y Zhang, Qingqing Cao, Madhumita Mahalanabis, and Catherine Klapperich)Microfluidic Devices for Cellular Proteomic Studies (Yihong Zhan and Chang Lu)Microfluidics for Neuroscience: Novel Tools and Future Implications (Vivian M Hernandez and P Hande Özdinler)Microfluidics: On-Chip Platforms as In Vitro Disease Models (Shan Gao, Erkin Şeker, and Martin L Yarmush)Application of Microfluidics in Stem Cell and Tissue Engineering (Sasha H Bakhru, Christopher Highley, and Stefan Zappe)Microfluidic “On-the-Fly” Fabrication of Microstructures for Biomedical Applications (Edward Kang, Sau Fung Wong, and Sang-Hoon Lee)Microfluidics as a Promising Tool Toward Distributed Viral Detection (Elodie Sollier and Dino Di Carlo)Electrophoresis and Dielectrophoresis for Lab-on-a-Chip (LOC) Analyses (Yağmur Demircan, Gürkan Yilmaz, and Haluk Külah)Ultrasonic Embossing of Carbon Nanotubes for the Fabrication of Polymer Microfluidic Chips for DNA Sample Purification (Puttachat Khuntontong, Min Gong, and Zhiping Wang)Ferrofluidics (A Rezzan Kose and Hur Koser)Antibody-based Blood Bioparticle Capture and Separation Using Microfluidics for Global Health (ZhengYuan Luo, ShuQi Wang, Utkan Demirci, TianJian Lu, Feng Xu, and BoFeng Bai)Applications of Quantum Dots for Fluorescence Imaging in Biomedical Research (ShuQi Wang, Matin Esfahani, Dusan Sarenac, Bettina Cheung, Aishwarya Vasudevan, Fatih Inci, and Utkan Demirci) Readership: Engineers, academic researchers and instructors, and industry researchers involved in microfluidic technologies. Keywords:Point-of-Care;Rapid Detection and Monitoring;Infectious Diseases;Biomedical Engineering / Bioengineering;Stem Cells Research;Biotechnology;Tissue Engineering

Now in its Third Edition, the Artech House bestseller, Fundamentals and Applications of Microfluidics, provides engineers and students with the most complete and current coverage of this cutting-edge field. This revised and expanded edition provides updated discussions throughout and features critical new material on microfluidic power sources, sensors, cell separation, organ-on-chip and drug delivery systems, 3D culture devices, droplet-based chemical synthesis, paper-based microfluidics for point-of-care, ion concentration polarization, micro-optofluidics and micro-magnetofluidics. The book shows how to take advantage of the performance benefits of microfluidics and serves as an instant reference for state-of-the-art microfluidics technology and applications. Readers find discussions on a wide range of applications, including fluid control devices, gas and fluid measurement devices, medical testing equipment, and implantable drug pumps. Professionals get practical guidance in choosing the best fabrication and enabling technology for a specific microfluidic application, and learn how to design a microfluidic device. Moreover, engineers get simple calculations, ready-to-use data tables, and rules of thumb that help them make design decisions and determine device characteristics quickly.

Biomedical Applications of Microfluidic Devices introduces the subject of microfluidics and covers the basic principles of design and synthesis of actual microchannels. The book then explores how the devices are coupled to signal read-outs and calibrated, including applications of microfluidics in areas such as tissue engineering, organ-on-a-chip devices, pathogen identification, and drug/gene delivery. This book covers high-impact fields (microarrays, organ-on-a-chip, pathogen detection, cancer research, drug delivery systems, gene delivery, and tissue engineering) and shows how microfluidics is playing a key role in these areas, which are big drivers in biomedical engineering research. This book addresses the fundamental concepts and fabrication methods of microfluidic systems for those who want to start working in the area or who want to learn about the latest advances being made. The subjects covered are also an asset to companies working in this field that need to understand the current state-of-the-art. The book is ideal for courses on microfluidics, biosensors, drug targeting, and BioMEMs, and as a reference for PhD students. The book covers the emerging and most promising areas of biomedical applications of microfluidic devices in a single place and offers a vision of the future. Covers basic principles and design of microfluidics devices Explores biomedical applications to areas such as tissue engineering, organ-on-a-chip, pathogen identification, and drug and gene delivery Includes chemical applications in organic and inorganic chemistry Serves as an ideal text for courses on microfluidics, biosensors, drug targeting, and BioMEMs, as well as a reference for PhD students