Microscopic Magnetic Resonance Imaging

In the past two decades, significant advances in magnetic resonance microscopy (MRM) have been made possible by a combination of higher magnetic fields and more robust data acquisition technologies. This technical progress has enabled a shift in MRM applications from basic anatomical investigations to dynamic and functional studies, boosting the use of MRM in biological and life sciences. This book provides a simple introduction to MRM emphasizing practical aspects relevant to high magnetic fields. It focuses on biological applications and presents a number of selected examples of neuroscience applications. The text is mainly intended for those who are beginning research in the field of MRM or are planning to incorporate high-resolution MRI in their neuroscience studies.

Magnetic Resonance Microscopy Explore the interdisciplinary applications of magnetic resonance microscopy in this one-of-a-kind resource In Magnetic Resonance Microscopy: Instrumentation and Applications in Engineering, Life Science and Energy Research, a team of distinguished researchers delivers a comprehensive exploration of the use of magnetic resonance microscopy (MRM) and similar techniques in an interdisciplinary milieux. Opening with a section on hardware and methodology, the book moves on to consider developments in the field of mobile nuclear magnetic resonance. Essential processes, including filtration, multi-phase flow and transport, and a wide range of systems – from biomarkers via single cells to plants and biofilms – are discussed next. After a fulsome treatment of MRM in the field of energy research, the editors conclude the book with a chapter extoling the virtues of a holistic treatment of theory and application in MRM. Magnetic Resonance Microscopy: Instrumentation and Applications in Engineering, Life Science and Energy Research also includes: A thorough introduction to recent developments in magnetic resonance microscopy hardware and methods, including ceramic coils for MR microscopy Comprehensive explorations of applications in chemical engineering, including ultra-fast MR techniques to image multi-phase flow in pipes and reactors Practical discussions of applications in the life sciences, including MRI of single cells labelled with super paramagnetic iron oxide nanoparticles In-depth examinations of new applications in energy research, including spectroscopic imaging of devices for electrochemical storage Perfect for practicing scientists from all fields, Magnetic Resonance Microscopy: Instrumentation and Applications in Engineering, Life Science and Energy Research is an ideal resource for anyone seeking a one-stop guide to magnetic resonance microscopy for engineers, life scientists, and energy researchers.

This handbook and ready reference covers materials science applications as well as microfluidic, biomedical and dental applications and the monitoring of physicochemical processes. It includes the latest in hardware, methodology and applications of spatially resolved magnetic resonance, such as portable imaging and single-sided spectroscopy. For materials scientists, spectroscopists, chemists, physicists, and medicinal chemists.

Although nuclear magnetic resonance is perhaps best known for its spectacular utility in medical tomography, its potential applicability to fields such as biology, materials science, and chemical physics is being increasingly recognized as laboratory NMR spectrometers are adapted to enable small scale imaging. This excellent introduction to the subject explores principles and common themes underlying two key variants of NMR microscopy, and provides many examples of their use. Methods discussed are not only important to fundamental biological and physical research, but have applications to a wide variety of industries, including those concerned with petrochemicals, polymers, biotechnology, food processing, and natural product processing. The wide range of scientists interested in NMR microscopy will want to own a copy of this book.

Magnetic resonance microscopy is a rapidly developing field of research plications in a variety of different areas. This book is based on lectur n at the International Conference on NMR Microscopy held in Heidelberg i mber 1991. It is, however, far more than the proceedings of this meeting ecturers have provided in depth contributions on their fields. The topics are * magnetic resonance imaging methods (NMR and ESR) * applications to materials science * imaging of flow and diffusion * applications in biomedicine and agriculture For the first time both an extensive overview and an up-to-date source of references on primarily nonmedical imaging are given. The book will stimulate the further development and application of magnetic resonance imaging as an analytical tool in industry and in research.

'Spatially Resolved Magnetic Resonance' provides comprehensive and exhaustive coverage of the state of the art in magnetic resonance imaging. Focusing on nonclinical applications, readers learn about the possibilities, limitations and strengths of magnetic resonance methods in a broad range of fields, from materials science, medicine, biology, to geology and ecology. New and innovative applications such as polymer and elastomer characterization, analysis of construction materials and material flow, biomedical imaging and plant studies document the significant advances being made in this field. Newcomers will find the tutorial chapter an excellent guide to the fundamentals of magnetic resonance. Based on lectures presented at the Fourth International Conference on Magnetic Resonance Microscopy held in Albuquerque, New Mexico, in October 1997, all chapters have been carefully edited and reviewed. Chemists, physicists, materials scientists, geologists, and life-scientists who wish to assess the potential of magnetic resonance imaging will find this reference a stimulating and exhaustive resource. 'This volume documents a long stride toward maturation and integration, along with the ever increasing power and subtlety of techniques and analyses, and should inspire developers and users in all areas, from medicine to geology.' Paul C. Lauterbur

Today, smaller and smaller electron and nuclear magnetic resonance structures are extensively studied both from an applied and from a fundamental point of view. The powerful tool of magnetic resonance imaging (MRI) has demonstrated that it is possible to visualize subsurface three dimensional structures with micrometer resolution containing 1012 nuclear spins; nuclear magnetic resonance (NMR) spectroscopy has the capacity to determine the three dimensional structure of biological macromolecules. Owing to the larger gyromagnetic ratio of electrons as compared to paramagnetic nuclei, electron spin resonance (ESR) has pushed detection sensitivity to 107 spins . Finally, a single electron spin has been detected by magnetic resonance force microscopy (MRFM), employing a device which combines two sensing technologies, namely magnetic resonance imaging (MRI) and atomic force microscopy (AFM). The ultimate goal of MRFM is to map the interior of a material sample, such as a complicated semiconductor structure or a bio-molecule, at atomic scale resolution.