Molecular Genetics Of Bacteria

This advanced level textbook offers an in-depth look at molecular biology and biochemistry. The breadth and diversity of bacterial genetics are explored in discussions of microbial systems beyond the much-studied E Coli.

The single most comprehensive and authoritative textbook on bacterial molecular genetics Snyder & Champness Molecular Genetics of Bacteria is a new edition of a classic text, updated to address the massive advances in the field of bacterial molecular genetics and retitled as homage to the founding authors. In an era experiencing an avalanche of new genetic sequence information, this updated edition presents important experiments and advanced material relevant to current applications of molecular genetics, including conclusions from and applications of genomics; the relationships among recombination, replication, and repair and the importance of organizing sequences in DNA; the mechanisms of regulation of gene expression; the newest advances in bacterial cell biology; and the coordination of cellular processes during the bacterial cell cycle. The topics are integrated throughout with biochemical, genomic, and structural information, allowing readers to gain a deeper understanding of modern bacterial molecular genetics and its relationship to other fields of modern biology. Although the text is centered on the most-studied bacteria, Escherichia coli and Bacillus subtilis, many examples are drawn from other bacteria of experimental, medical, ecological, and biotechnological importance. The book's many useful features include Text boxes to help students make connections to relevant topics related to other organisms, including humans A summary of main points at the end of each chapter Questions for discussion and independent thought A list of suggested readings for background and further investigation in each chapter Fully illustrated with detailed diagrams and photos in full color A glossary of terms highlighted in the text While intended as an undergraduate or beginning graduate textbook, Molecular Genetics of Bacteria is an invaluable reference for anyone working in the fields of microbiology, genetics, biochemistry, bioengineering, medicine, molecular biology, and biotechnology. "This is a marvelous textbook that is completely up-to-date and comprehensive, but not overwhelming. The clear prose and excellent figures make it ideal for use in teaching bacterial molecular genetics." —Caroline Harwood, University of Washington

Providing the single most comprehensive and authoritative textbook on bacterial molecular genetics, this updated edition provides descriptive background information, detailed experimental methods, examples of genetic analyses, and advanced material relevant to current applications of molecular genetics.

Providing the single most comprehensive and authoritative textbook on bacterial molecular genetics, this updated edition provides descriptive background information, detailed experimental methods, examples of genetic analyses, and advanced material relevant to current applications of molecular genetics.

Presenting the basic concepts and most exciting developments, this textbook provides an introduction to the molecular genetics of bacteria in a form suitable for the needs of students studying microbiology, biotechnology, molecular biology, biochemistry, genetics and related biomedical sciences.

The fifth edition of this highly successful book provides studentswith an essential introduction to the molecular genetics ofbacteria covering the basic concepts and the latest developments.It is comprehensive, easy to use and well structured with cleartwo-colour diagrams throughout. Specific changes to the new edition include: More detail on sigma factors, anti-sigma factors and anti-antisigma factors, and the difference in the frequency of sigma factorsin bacteria Expand material on integrons as these are becoming increasinglyimportant in antibiotic resistance Enhanced treatment of molecular phylogeny Complete revision and updating of the final chapter on‘Gene Mapping and Genomics’ Two-colour illustrations throughout. The focus of the book remains firmly on bacteria and will beinvaluable to students studying microbiology, biotechnology,molecular biology, biochemistry, genetics and related biomedicalsciences.

Molecular Genetics of Bacteria is the single most comprehensive and authoritative textbook on bacterial molecular genetics. Perfect for advanced undergraduate and graduate-level courses, the text presents the latest research on the subject in a clearly written and well-illustrated style. This book is intended for students and professionals in the fields of microbiology, genetics, biochemistry, bioengineering, medicine, molecular biology, and biotechnology.

Described as the earliest, simplest life forms, with unlimited metabolic versatility, bacteria are ideally suited to answer some very fundamental questions on life and its processes. They have been employed in almost all fields of biological studies, including Genetics. The whole edifice of science of Genetics centers around three processes: the generation, expression, and transmission of biological variation, and bacteria offer immediate advantages in studying all the three aspects of heredity. Being haploid and structurally simple, it becomes easy to isolate mutations of various kinds and relate them to a function. The availability of such mutants and their detailed genetic and biochemical analyses lead to a gamut of information on gene expression and its regulation. While studying the transmission of biological variation, it is clear that unlike their eukaryotic counterpart, a more genetic approach needs to be employed. Transmission of genetic information in most eukaryotic organisms rests on sexual reproduction that allows the generation of genetically variable offspring through the process of gene recombination. Even though bacteria show an apparent preference for asexual reproduction, they too have evolved mechanisms to trade their genetic material. In fact, bacteria not only could acquire many genes from close relatives, but also from entirely distant members through the process of horizontal gene transfer. Their success story of long evolutionary existence will stand testimony to these mechanisms. While teaching a course on Microbial Genetics to the post-graduate students at Delhi University, it was realized that a book devoted to bacterial genetics may be very handy to the students, researchers, and teachers alike. A strong foundation in genetics also helps in comprehending more modern concepts of molecular biology and recombinant DNA technology, always a favorite with the students and researchers. Planning the format of the book, emphasis has been laid on the generation and transmission of biological variability. The omission of expression part is indeed intentional because lots of information is available on this aspect in any modern biology book. The contents are spread over seven chapters and the text is supported with figures/tables wherever possible. The endeavor has been to induce the readers to appreciate the strength of bacterial genetics and realize the contribution of these tiny organisms to the growth of biological sciences as a whole and genetics in particular.