Molecular Imaging In Multiple Myeloma

This book provides a comprehensive overview of the importance of molecular imaging in multiple myeloma, with detailed explanation of its clinical impact. Other important features are the definition of criteria that will aid PET/CT interpretation; identification and explanation of the most frequent pitfalls; a brief overview of the advantages and limitations of DWI MR imaging, still an experimental technique in multiple myeloma; and examination of the possible role of emerging PET tracers. When appropriate, clinical cases are used to illustrate key teaching points. All physicians involved in oncological imaging should regularly reassess and update their routine practice in the evaluation of multiple myeloma patients. This is especially true now, given the recent clarification by the International Myeloma Working Group (IMWG) of the criteria for bone damage requiring therapy and the emerging data supporting the role of the newer functional imaging techniques in predicting outcome and/or evaluating response to therapy. In this challenging context, Molecular Imaging in Multiple Myeloma will be of high value for nuclear medicine physicians, radiologists, and hematologists.

This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.

On account of its unrivalled imaging capabilities and sensitivity, magnetic resonance imaging (MRI) is considered the modality of choice for the investigation of physiologic and pathologic processes affecting the bone marrow. This book describes the MRI appearances of both the normal bone marrow, including variants, and the full range of bone marrow disorders. Detailed discussion is devoted to malignancies, including multiple myeloma, lymphoma, chronic myeloproliferative disorders, leukemia, and bone metastases. Among the other conditions covered are benign and malignant compression fractures, osteonecrosis, hemolytic anemia, Gaucher’s disease, bone marrow edema syndrome, trauma, and infective and non-infective inflammatory disease. Further chapters address the role of MRI in assessing treatment response, the use of contrast media, and advanced MRI techniques. Magnetic Resonance Imaging of the Bone Marrow represents an ideal reference for both novice and experienced practitioners.

This book provides a review of imaging techniques and applications in stem cell transplantation and other cell-based therapies. The basis of different molecular imaging techniques is explained in detail, as is the current state of interventional radiology techniques. While the whole is a comprehensive discussion, each chapter is self-sufficient enough so that each can be reviewed independently. The contributors represent years of international and cross-disciplinary expertise and perspective and are all well known in their fields. comprehensive information on the role of clinical and molecular imaging in stem cell therapy from this book reviewed in detail. Essential reading for radiologists and physicians who are interested in developing a basic understanding of stem cell imaging and applications of stem cells and cell based therapies. However, it will also be of interest to clinical scientists and researchers alike, including those involved in stem cell labeling, tracking & imaging, cancer therapy, angiogenesis and cardiac regeneration.

This book provides the reader with a comprehensive understanding of both the basic principles and the clinical applications of nuclear oncology imaging techniques. The authors have assembled a distinguished group of leaders in the field who provide valuable insight on the subject. The book also includes major chapters on the cancer patient and the pathophysiology of abnormal tissue, the evaluation of co-existing disease, and the diagnosis and therapy of specific tumors using functional imaging studies. Each chapter is heavily illustrated to assist the reader in understanding the clinical role of nuclear oncology in cancer disease therapy and management.

Musculoskeletal Imaging: The Requisites, 4th Edition delivers the conceptual, factual, and interpretive information you need for effective clinical practice in musculoskeletal imaging, as well as for certification and recertification review. Master core knowledge the easy and affordable way with clear, concise text enhanced by at-a-glance illustrations, boxes, and tables - all completely rewritten to bring you up to date. Find key information easily with numerous outlines, tables, "pearls," and boxed material for easy reading and reference. Access the fully searchable text and downloadable images online at www.expertconsult.com. Get the best results from today's most technologically advanced approaches, including new uses of MR and ultrasound for early diagnosis and monitoring of inflammatory arthritis. Prepare for the written board exam and for clinical practice with critical information on femoroacetabular impingement, arthrography, hip replacement, cartilage tumors, bone marrow imaging (including focal and diffuse replacement), and sports medicine (including athletic pubalgia/sports hernia). Stay up to date on soft tissue tumors with significantly expanded content, illustrated tumor-specific findings, and new AJCC staging and diagnostic information. Clearly visualize the findings you're likely to see in practice and on exams with 300 new MRI, CT, ultrasound, and x-ray images throughout.

In this issue of Radiologic Clinics, Guest Editors Jonathan E. McConathy and Samuel J. Galgano bring their considerable expertise to the topic of PET Imaging. Top experts in the field cover key topics such as PET Imaging for lung cancer, breast cancer, melanoma, and more. Provides in-depth, clinical reviews on PET Imaging, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 13 relevant, practice-oriented topics including PET Imaging for hematologic malignancies, neuroendocrine tumors, prostate and genitourinary cancers, and more.