Multifunctional Hydrogels For Biomedical Applications

Multifunctional Hydrogels for Biomedical Applications Comprehensive resource presenting a thorough overview of the biomedical applications of hydrogels This book provides an overview of the development and applications of the clinically relevant hydrogels that are used particularly in tissue engineering, regenerative medicine, and drug delivery. Taking a multidisciplinary approach, it goes through the material from chemistry, materials science, biology, medicine, nanotechnology, and bioengineering points of view. Sample topics covered by the three well-qualified editors include: The design, functions, and developments of hydrogels Proteins and polysaccharides that mimic extracellular matrix Generation and applications of supramolecular hydrogels Design and functions of cell encapsulation systems Multifunctional Hydrogels for Biomedical Applications is a useful all-in-one reference work for materials scientists, polymer chemists, and bioengineers which provides a comprehensive, contemporary understanding of hydrogels and their applications targeting a wide variety of pathologies.

Hydrogels are important polymer-based materials with innate fascinating properties and applications: they are three-dimensional, hydrophilic, polymeric networks that can absorb large amounts of water or aqueous fluids and are biocompatible, mechanically flexible, and soft. The incorporation of functionalities to develop smart and bioactive platforms has led to a myriad of applications. This book offers a comprehensive overview of multifunctional hydrogels, covering fundamentals, properties, and advanced applications in a progressive way. While each chapter can be read stand-alone, together they clearly describe the fundamental concepts of design, synthesis, and fabrication, as well as properties and performances of smart multifunctional hydrogels and their advanced applications in the biomedical, environmental, and robotics fields. This book: • Introduces readers to different hydrogel materials and the polymer types used to fabricate them. • Discusses conducting polymer hydrogels, nanocomposite hydrogels, and self-healing hydrogels. • Covers synthesis methodologies and fabrication techniques commonly used to confer certain structures and/or architectures. • Shows how hydrogels can be modified to incorporate new functionalities able to respond to physical and/or chemical changes. • Examines applications including bioelectronics, sensors and biosensors, tissue engineering, drug delivery, antipathogen applications, cancer theranostics, environmental applications, and soft robotics, with chapters showcasing the main advances achieved up to date in every field. Multifunctional Hydrogels: From Basic Concepts to Advanced Applications serves as a valuable resource for academic and industry researchers from interdisciplinary fields including materials science, chemistry, chemical engineering, bioengineering, physics, and pharmaceutical engineering.

Multifunctional Hydrogels for Biomedical Applications Comprehensive resource presenting a thorough overview of the biomedical applications of hydrogels This book provides an overview of the development and applications of the clinically relevant hydrogels that are used particularly in tissue engineering, regenerative medicine, and drug delivery. Taking a multidisciplinary approach, it goes through the material from chemistry, materials science, biology, medicine, nanotechnology, and bioengineering points of view. Sample topics covered by the three well-qualified editors include: The design, functions, and developments of hydrogels Proteins and polysaccharides that mimic extracellular matrix Generation and applications of supramolecular hydrogels Design and functions of cell encapsulation systems Multifunctional Hydrogels for Biomedical Applications is a useful all-in-one reference work for materials scientists, polymer chemists, and bioengineers which provides a comprehensive, contemporary understanding of hydrogels and their applications targeting a wide variety of pathologies.

This book explores the potential of hydrogels as a multiutility system and their benefits (biocompatibility, degradability, and supporting scaffolds) for a wide range of applications in diagnostics and therapeutics. It also discusses the future prospects and challenges facing hydrogels. A wide variety of smart hydrogels (conducting, stimuli responsive, and others) with possible biomedical applications are elaborated. The book demonstrates the effectiveness of hydrogels in diagnostics of diseases in various in vivo and in vitro environments and highlights the engineering/functionalization of hydrogels for everyday drug dosage as an efficient drug carrier, scaffold, and sensing application. Explores the potential of hydrogels as a multifunctional system and their benefits, particularly for biomedical applications in diagnostics as well as therapeutics. Highlights the designing and engineering of hydrogels for everyday drug dosage and possible functionalization to fabricate an efficient drug carrier. Examines the significance of biopolymer-based hydrogels and their responsiveness in different physiological fluids. Demonstrates the effectiveness of hydrogels in diagnostics of diseases in various in,vivo and in,vitro environments. Presents challenges associated with the hydrogels and discusses possible in-hand modifications at length. Dr. Anujit Ghosal worked in the School of Biotechnology, Jawaharlal Nehru University, India. Currently, he is affiliated with the School of Life Sciences, Beijing Institute of Technology, Beijing, PRC. Dr. Ghosal researches in biochemistry, polymer chemistry, and nanotechnology. He has been the recipient of prestigious fellowships throughout his research career. His research ability is proven by his published peer-reviewed research and review articles and contributed book chapters. Dr. Ajeet Kaushik works as an assistant professor of chemistry and is exploring advanced electrochemical sensing systems and nanomedicine for personalized health wellness at the Department of Natural Sciences of the Division of Science, Arts, and Mathematics at Florida Polytechnic University, Lakeland, US. He is the recipient of various reputed awards for his service in the area of nanobiotechnology for health care. His excellent research credentials are reflected by his four edited books, 100 international research peer-reviewed publications, and three patents in the area of nanomedicine and smart biosensors for personalized health care.

This book discusses recent advances in hydrogels, including their generation and applications and presents a compendium of fundamental concepts. It highlights the most important hydrogel materials, including physical hydrogels, chemical hydrogels, and nanohydrogels and explores the development of hydrogel-based novel materials that respond to external stimuli, such as temperature, pressure, pH, light, biochemicals or magnetism, which represent a new class of intelligent materials. With their multiple cooperative functions, hydrogel-based materials exhibit different potential applications ranging from biomedical engineering to water purification systems. This book covers key topics including superabsorbent polymer hydrogel; intelligent hydrogels for drug delivery; hydrogels from catechol-conjugated materials; nanomaterials loaded hydrogel; electrospinning of hydrogels; biopolymers-based hydrogels; injectable hydrogels; interpenetrating-polymer-network hydrogels: radiation- and sonochemical synthesis of micro/nano/macroscopic hydrogels; DNA-based hydrogels; and multifunctional applications of hydrogels. It will prove a valuable resource for researchers working in industry and academia alike.

Hydrogels, as three-dimensional polymer networks, are able to retain a large amount of water in their swollen state. The biomedical application of hydrogels was initially hampered by the toxicity of cross-linking agents and the limitations of hydrogel formation under physiological conditions. However, emerging knowledge in polymer chemistry and an increased understanding of biological processes have resulted in the design of versatile materials and minimally invasive therapies.The novel but challenging properties of hydrogels are attracting the attention of researchers in the biological, medical, and pharmaceutical fields. In the last few years, new methods have been developed for the preparation of hydrophilic polymers and hydrogels, which may be used in future biomedical and drug delivery applications. Such efforts include the synthesis of self-organized nanostructures based on triblock copolymers with applications in controlled drug delivery. These hydrogels could be used as carriers for drug delivery when combined with the techniques of drug imprinting and subsequent release. Engineered protein hydrogels have many potential advantages. They are excellent biomaterials and biodegradables. Furthermore, they could encapsulate drugs and be used in injectable forms to replace surgery, to repair damaged cartilage, in regenerative medicine, or in tissue engineering. Also, they have potential applications in gene therapy, although this field is relatively new.

Engineering of Natural Polymeric Gels and Aerogels for Multifunctional Applications brings together detailed information on gels, hydrogels, and aerogels derived from natural polymers, covering materials, processing, fabrication techniques, structure-property relationships, and novel applications. The book begins by introducing polymeric gels, hydrogels, and aerogels, the different types and properties, advantages and disadvantages, manufacturing techniques, production and scalability, and the possible applications. This is followed by thorough coverage of processing methods for obtaining natural polymer-based gels and hydrogels, with separate chapters focusing on physical processes, chemical processes, green processes, and processing for aerogels. The final chapters of the book focus on the preparation of natural polymer-based gels, hydrogels, and aerogels for many state-of-the-art applications, including biomedical, absorbent, energy saving, filtration, and sensing areas. Engineering of Natural Polymeric Gels and Aerogels for Multifunctional Applications is an essential resource for all those with an interest in polymeric gels and natural polymers, including researchers and scientists in polymer engineering, polymer chemistry, sustainable materials, biomaterials, materials science and engineering, and chemical engineering. In industry, this book supports scientists, R&D, and engineers looking to utilize novel bio-based materials for advanced applications. Covers the physical, chemical, and green processing methods for obtaining gels, hydrogels, and aerogels from natural polymers Explores a range of cutting-edge uses, including in biomedical, absorbent, energy-saving, filtration, and bio-sensing applications Presents the latest innovations in the field, including the preparation of lightweight, highly open porous polysaccharide and protein aerogels

This cutting edge book provides all the important aspects dealing with the basic science involved in materials in biomedical technology, especially structure and properties, techniques and technological innovations in material processing and characterizations, as well as the applications. The volume consists of 12 chapters written by acknowledged experts of the biomaterials field and covers a wide range of topics and applications including: The different types of nanobiomaterials How to generate porous biomaterials for tissue engineering Calcium phosphate-based biomaterials intended for mineralized tissue regenerative applications Nanocrystalline form of calcium phosphates Design and fabrication of SiO2 nanoparticles New kinds of titanium alloy implants Injectable growth factor system based on bone morphogenetic proteins Impedance sensing of biological processes in mammalian cells Hydrogels-based implantable glucose sensors Molecular design of multifunctional polymers for gene transfection Hydrogels and their potential biomedical applications Hybrid biomaterials with high mechanical and biological properties