Multiple Sclerosis

Multiple Sclerosis
Author: Institute of Medicine,Board on Neuroscience and Behavioral Health,Committee on Multiple Sclerosis: Current Status and Strategies for the Future
Publsiher: National Academies Press
Total Pages: 457
Release: 2001-08-10
Genre: Medical
ISBN: 9780309072854

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Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.

Multiple Sclerosis

Multiple Sclerosis
Author: Ian S. Zagon,Patricia J. McLaughlin
Publsiher: Unknown
Total Pages: 137
Release: 2017
Genre: Electronic Book
ISBN: 0994438133

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Fast Facts Multiple Sclerosis

Fast Facts  Multiple Sclerosis
Author: Stella E. Hughes,Gabrielle Macaron
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 166
Release: 2021-05-19
Genre: Medical
ISBN: 9783318067972

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Multiple sclerosis (MS) is a leading cause of disability in young adults, carrying a considerable individual and societal economic burden. The development of disease-modifying therapies and updates to diagnostic criteria are leading us into a new era for MS management, both in the earliest disease phases and progressive MS. In this completely revised/fully updated edition of Fast Facts: Multiple Sclerosis, we present the most recent evidence on disease pathogenesis and all clinical aspects of the condition, as well as the latest on disease-modifying therapies and other potential treatments. Given the need for multidisciplinary management of MS, we have written this resource for the benefit of all health professionals involved in MS care. Table of Contents: • Epidemiology and genetics • Pathology • The clinical picture • Treatment of relapses and symptoms • Disease-modifying treatment • Emerging therapies • Special MS populations • Lifestyle considerations and the multidisciplinary team • Advanced MS

Multiple Sclerosis

Multiple Sclerosis
Author: Rheinard Hohlfeld,Chris Polman,Alan J Thompson
Publsiher: CRC Press
Total Pages: 384
Release: 1997-01-01
Genre: Medical
ISBN: 1853174289

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This excellent book provides a fresh approach to multiple sclerosis, detailing the newest developments in a lively style. Particular emphasis is placed on areas of controversy and uncertainty The information conveyed is accessible to all practitioners in the field of multiple sclerosis.

Neuroimmune Diseases

Neuroimmune Diseases
Author: Hiroshi Mitoma,Mario Manto
Publsiher: Springer
Total Pages: 822
Release: 2019-08-13
Genre: Medical
ISBN: 9783030195151

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A translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases

McAlpine s Multiple Sclerosis

McAlpine s Multiple Sclerosis
Author: Alastair Compston,Douglas McAlpine
Publsiher: Unknown
Total Pages: 620
Release: 1998
Genre: Multiple sclerosis
ISBN: UOM:39015046891498

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This is the latest edition of the classic book on the subject of multiple sclerosis. An international group of authors has been involved in updating this edition which features more information on imaging and investigations, and a new chapter on neurobiology and glial development.

Multiple Sclerosis and Related Disorders

Multiple Sclerosis and Related Disorders
Author: Douglas S. Goodin
Publsiher: Elsevier
Total Pages: 736
Release: 2014-02-05
Genre: Medical
ISBN: 9780444633095

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Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. MS causes an inflammatory response in the central nervous system leading to neurodegeneration, oligodendrocyte death, axonal damage, and gliosis. Over the past five years ongoing research has greatly expanded our understanding of the pathogenesis of MS, detailed insight into the epidemiology and genetic factors related to MS, the introduction of new technologies and tests to better diagnose and predict the future course of the disease and the introduction of new treatments targeting MS. This collection of review chapters provides a comprehensive reference into the science and clinical applications of the latest Multiple Sclerosis research and will be a valuable resource for the neuroscience research community and the clinical neurology community of researchers and practitioners. A comprehensive tutorial reference detailing our current foundational understanding of Multiple Sclerosis Includes chapters on key topics including the genetics of MS, MRI imaging and MS, and the latest treatment options Each chapter is translational and focuses on current research and impact on diagnosis and treatment options

Emerging Drugs and Targets for Multiple Sclerosis

Emerging Drugs and Targets for Multiple Sclerosis
Author: Ana Martinez
Publsiher: Royal Society of Chemistry
Total Pages: 350
Release: 2019-06-28
Genre: Science
ISBN: 9781788014502

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Multiple sclerosis (MS) is a complex disease with a presumed autoimmune aetiology and few current effective treatments. Disease modifying therapies focus on the altering the natural course of relapsing and remitting MS, targeting the inflammatory response. Other targets involve tacking the cause of the disease – demyelination of axons through remyelination therapies. Due to several recent breakthroughs in the understanding of the pathophysiology of MS new targets for remyelination and immunomodulation are rapidly emerging. This book provides a comprehensive overview of drug discovery and development for the molecular basis of the disease, from new targets to drugs currently in clinical development, cellular and animal disease models to biomarkers for diagnosis and assessment in clinical trials. Emerging Drugs and Targets for Multiple Sclerosis is an ideal reference for any student or researcher interested in drug development for neurodegenerative diseases, autoimmune diseases and MS in particular.