Neurodevelopmental Disorders

Neurodevelopmental Disorders, the latest release in the Comprehensive Developmental Neuroscience series, presents the most thorough coverage available, addressing all aspects on how the nervous system and its components develop. This book brings together the latest research in this rapidly evolving field, with section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on neurodevelopmental disorders in humans and experimental organisms. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Covers disorders of the nervous system that arise through defects in neural development

From autism to ADHD to learning disabilities, a guide for all teachers to this constellation of disorders. Developmental deficits in learning and communication in young children are defined as neurodevelopmental disorders. This constellation, newly defined in the DSM-5, represents a range of issues that educators must address. Neurodevelopmental Disorders: A Definitive Guide for Educators provides extensive and practical information to a range of professionals, and to all others who are interested in the complex and often misunderstood disabilities that fall within the general medical and psychological diagnostic categories of neurodevelopmental disability. Noted psychologist and educator Dr. Frank E. Vargo provides a comprehensive overview of neurodevelopmental deficits and disabilities, as well as of their related learning and cognitive processes, with a strong focus on educational considerations, applications, and relevance across academic areas and with a mind to global educational models. Well researched and accessibly written, this book is an up-to-date and authoritative reference to all of the educational and clinical topics in the diagnostic categories of neurodevelopmental disorder. This informative book will provide a primary reference source for all educators, school and clinical psychologists, clinical mental health counselors and therapists, special education and medical professionals, and parents of children with special needs.

Neurodevelopmental Disorders in Children and Adolescents provides an innovative perspective on developmental disorders in youth, one focused on embracing and working with the "messiness" and many variables at play in child and adolescent development. The volume’s approach is aligned with the NIMH Research Domain Criteria project, which hopes to move away from categorical diagnosis toward multidimensional analysis. Each chapter focuses on a particular aspect of development, cluster of diagnoses, or clinical concern. The book also emphasizes humility, an awareness of diversity and difference without stigma, and support for collaborative and integrative healthcare. This is an essential volume for practitioners hoping to improve how they evaluate and treat developmental disorders in children.

Neurodevelopmental disorders arise from disturbances to various processes of brain development, which can manifest in diverse ways. They encompass many rare genetic syndromes as well as common, heritable conditions such as intellectual disability, autism, ADHD, schizophrenia and many types of epilepsy. The Genetics of Neurodevelopmental Disorders examines recent revolutionary advances in our understanding of the genetics of these disorders, exploring both basic discoveries and the translation of new findings into the clinical setting. The book begins by examining the genetic architecture and etiology of neurodevelopmental disorders. It describes the striking recent progress in identifying pathogenic mutations, which are grouped here based on the neurodevelopmental processes impacted. Subsequent chapters consider the use of cellular and animal models to elucidate the cascading consequences of such mutations, from molecular and cellular levels to emergent effects on neural circuits, brain systems and subsequent psychological development. The text concludes by examining the important clinical implications of the recent advances in the field, from recognition of the genetic causes in individual patients to development of new treatments and interventions. A timely synthesis, The Genetics of Neurodevelopmental Disorders is a unique and essential resource for neuroscientists, geneticists, neurologists and psychiatrists and an accessible and up-to-date overview for medical and science students.

Interest in the field of neurodevelopmental disorders has grown exponentially in recent years across a range of disciplines, including psychology, psychiatry, education and neuroscience. The research itself has become more sophisticated, using multidisciplinary methods to probe interdisciplinary questions. Neurodevelopmental Disorders: Research Challenges and Solutions provides a thorough overview of the key issues involved in researching neurodevelopmental disorders. The volume includes 14 chapters, arranged over three sections. Chapters in the first section address general research challenges for the study of neurodevelopmental disorders. The second section draws upon specific disorders (such as Williams syndrome, Autism Spectrum Disorders, Down Syndrome, Fragile X Syndrome, ADHD, and Language Disorders) to consider the syndrome-specific issues or challenges that may be crucial to advancing our understanding of aspects of cognition and behavior associated with them. The final section considers how research evidence may be translated into practice to begin making an impact upon the lives of individuals who have neurodevelopmental disorders and their families. Each chapter in the book also includes ‘practical tips’ for either conducting research with individuals who have neurodevelopmental disorders or considering wider practical issues. The book will be indispensable reading for advanced students, researchers, and practitioners in the fields of developmental psychology, developmental psychopathology, special needs education, neuropsychology, and neurodevelopmental disorders.

Content Description #"A Bradford Book."#Includes bibliographical references and index.

Nowadays, it is widely accepted that there is no single influence (be it nature or nurture) on cognitive development. Cognitive abilities emerge as a result of interactions between gene expression, cortical and subcortical brain networks, and environmental influences. In recent years, our study of neurodevelopmental disorders has provided much valuable information on how genes, brain development, behaviour, and environment interact to influence development from infancy to adulthood. This is the first book to present evidence on development across the lifespan across these multiple levels of description (genetic, brain, cognitive, environmental). In the book, the authors have chosen a well-defined disorder, Williams syndrome (WS), to explore the impact of genes, brain development, behaviour, as well as the individual's environment on development. WS is used as a model disorder to demonstrate the authors approach to understanding development, whilst being presented in comparison to other neurodevelopmental disorders - Autism, Developmental Dyscalculia, Down syndrome, Dyslexia, Fragile X syndrome, Prader-Willi syndrome, Specific Language Impairment, Turner syndrome - to illustrate differences in development across neurodevelopmental disorders. Williams syndrome is particularly informative for exploring development: Firstly, it has been extensively researched at multiple levels: genes, brain, cognition and behaviour, as well as in terms of the difficulties of daily living and social interaction. Secondly, it has been studied across the lifespan, with many studies on infants and toddlers with WS as well as a large number on children, adolescents and adults. The authors also explore a number of domain-general and domain-specific processes in the verbal, non-verbal and social domains, across numerous neurodevelopmental disorders. This illustrates, among other factors, the importance of developmental timing, i.e. that the development of a cognitive skill at a specific timepoint can impact on subsequent development within that domain, but also across domains. In addition, the authors discuss the value of investigating basic-level abilities from as close to the infant start-state as possible, presenting evidence of where cross-syndrome comparisons have shed light on the cascading impacts of subtle similarities and discrepancies in early delay or deviance, on subsequent development. Designed such that readers with an interest in any neurodevelopmental disorder can gain insight into the intricate dynamics of cognitive development, the book covers both theoretical issues and those of clinical relevance. It will be an invaluable reference for any researcher, clinician, student as well as interested parents or teachers wishing to learn about neurodevelopmental disorders from a developmental framework.

Nowadays, neurodevelopmental disorders comprise a large proportion of mental health diagnoses. These disorders, according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, include intellectual disabilities, communication disorders, autism spectrum disorders, attention deficit hyperactivity disorders, specific learning disorders, and motor disorders. Current research is pointing in the direction of schizophrenia, bipolar disorders, and other disorders being included in the category of neurodevelopmental disorders as well. There is a great deal of overlap among these disorders and they are best understood in a dimensional fashion. This book sets out the future of psychiatry in relation to these disorders and what is basically a new understanding of psychiatry in recent decades. Chapters cover topics such as early recognition of schizophrenia, epilepsy, and the genetics of ataxia telangiectasia. Also included is an examination of the complex issue of systems biology and neurodevelopment.