Neuroprosthetics

Although somatosensory system works in tandem with the motor system in biology, the majority of the prosthetics research and commercial efforts had focused on accommodating movement deficits. With the development of neuroprostheses in the last 15 years, it has become evident that somatosensory input (mainly as touch and proprioception) is essential for motor control, manipulating objects, and embodiment, in addition to its primary role for sensory perception. Somatosensory Feedback for Neuroprosthetics covers all relevant aspects to facilitate learning and doing research and development in the field. To understand the properties of the body to create viable solutions, this book starts with chapters reviewing the basic anatomy, physiology, and psychophysics of the somatosensory system, sensorimotor control, and instrumentation. Some sections are dedicated to invasive (peripheral and central, mainly cortical) and noninvasive (vibrotactile, electrotactile, etc.) approaches. Final chapters cover future technologies such as novel sensors and electrodes, safety, and clinical testing, and help to make up future prospects for this field with an emphasis on development and end use. With contributions from renowned experts, the contents include their recent findings and technical details necessary to understand those findings. Provides a concise review of the somatosensory system and latest advances in the use of somatosensory feedback for neuroprosthetics Analyzes many approaches to somatosensory feedback Provides the most detailed work on somatosensory neuroprostheses, their development, and applications in real life work.

Prostheses for the Brain: Introduction to Neuroprosthetics bridges the disciplines required in the field of neuroprosthetics and provides the interdisciplinary base required for understanding neuroprosthetic devices. It introduces basic aspects from the physical, bioengineering and medical perspectives, and forms a common knowledge base. It provides the entrance to the field and sets realistic expectations, both regarding potentials as well as limitations, for the devices in both design and outcomes. The book additionally reviews the technology behind the most frequently used and most clinically successful neuroprosthetic devices. It provides the physiological background for their function, as well as the technology behind them. Finally, the authors suggest future possible developments that may play crucial role in new prostheses for the brain. This gives the reader a comprehensive view on the principles and applications of neuroprostheses. This book has been built from the authors course they teach on neuroprostheses and is ideal for students, engineers and medical professionals in this field. Introduces the general principles of conductivity of electrolytes and the processes at the tissue–electrode interface Describes safety issues and regulatory rules, clarifies conceptual differences between stimulating and sensing electrodes Reviews stimulation strategies, tissue reactions, potential medical complications, brain adaptations and the clinically most successful applications of neuroprostheses

A study of neuroprosthetics. It is broadly divided into three sections which address: neuroanatomy and neurophysiology, biomaterials and biocompatibility, stimulation and recording techniques; clinical applications of neuroprosthetics; and future developments.

Master the tools of design thinking using Neuroprosthetics: Principles and Applications. Developed from successfully tested material used in an undergraduate and graduate level course taught to biomedical engineering and neuroscience students, this book focuses on the use of direct neural sensing and stimulation as a therapeutic intervention for complex disorders of the brain. It covers the theory and applications behind neuroprosthetics and explores how neuroprosthetic design thinking can enhance value for users of a direct neural interface. The book explains the fundamentals of design thinking, introduces essential concepts from neuroscience and engineering illustrating the major components of neuroprosthetics, and presents practical applications. In addition to describing the approach of design thinking (based on facts about the user’s needs, desires, habits, attitudes, and experiences with neuroprosthetics), it also examines how effectively "human centered" neuroprosthetics can address people’s needs and interactions in their daily lives. Identifying concepts and features of devices that work well with users of a direct neural interface, this book: Outlines the signal sensing capabilities and trade-offs for common electrode designs, and determines the most appropriate electrode for any neuroprosthetic application Specifies neurosurgical techniques and how electronics should be tailored to capture neural signals Provides an understanding of the mechanisms of neural–electrode performance and information contained in neural signals Provides understanding of neural decoding in neuroprosthetic applications Describes the strategies that can be used to promote long-term therapeutic interventions for humans through the use of neuroprosthetics The first true primary text for undergraduate and graduate students in departments of neuroscience and bioengineering that covers the theory and applications behind this science, Neuroprosthetics: Principles and Applications provides the fundamental knowledge needed to understand how electrodes translate neural activity into signals that are useable by machines and enables readers to master the tools of design thinking and apply them to any neuroprosthetic application.

This is an updated and abridged edition of the original volume published in 2004. Like its predecessor it is targeted for students of bioengineering, biomedical engineering, applied physiology, biological cybernetics and related fields; for engineers and scientists who have an interest in neuroprosthetics; and for medical practitioners using products of that field. The practice of neuroprosthetics requires a fundamental understanding of the anatomy and physiology of the nervous system, mathematical neurobiology, material science, electrochemistry, and electrophysiology. The text assumes some familiarity with basic anatomy, physiology, calculus, electrophysiology and bioinstrumentation, which typically are covered in undergraduate and first year graduate bioengineering curricula. These areas are also reviewed here, with the aim of consolidating principles fundamental to understanding the field. With that as background, the book then presents an overview of the field with detailed emphasis in selected areas of neural interfaces and neuroprostheses. The covered topics provide readers with sufficient information to understand the theory, rationale, design, and functioning of neuroprosthetic devices currently in clinical use and under development. The current volume is shorter than its predecessor. This has been achieved by reducing some of the repetition present in certain chapters of the earlier edition and eliminating a few chapters whose topics are now well covered in review literature readily available on the internet and elsewhere. Two chapters have been retained in their original versions to provide important background material, but the remaining chapters have either been revised by their original authors or replaced by new versions written by different authors. In addition new topics have been added to the section on existing systems.

Though there have been many developments in sensory/motor prosthetics, they have not yet reached the level of standard and worldwide use like pacemakers and cochlear implants. One challenging issue in motor prosthetics is the large variety of patient situations, which depending on the type of neurological disorder. To improve neuroprosthetic performance beyond the current limited use of such systems, robust bio-signal processing and model-based control involving actual sensory motor state (with biosignal feedback) would bring about new modalities and applications, and could be a breakthrough toward adaptive neuroprosthetics. Recent advances of Brain Computer Interfaces (BCI) now enable patients to transmit their intention of movement. However, the functionality and controllability of motor prosthetics itself can be further improved to take advantage of BCI interfaces. In this Research Topic we welcome contribution of original research articles, computational and experimental studies, review articles, and methodological advances related to biosignal processing that may enhance the functionality of sensory motor neuroprosthetics. The scope of this topic includes, but is not limited to, studies aimed at enhancing: 1) computational biosignal processing in EMG (Electromyography), EEG (Electroencephalography), and other modalities of biofeedback information; 2) the computational method in modeling and control of sensory motor neuroprosthetics; 3) the systematic functionality aiming to provide solutions for specific pathological movement disorders; 4) human interfaces such as BCI - but in the case of BCI study, manuscripts should be experimental studies which are applied to sensory/motor neuroprosthetics in patients with motor disabilities.

Neuroprosthetics is a fast-growing area that brings together the fields of biomedical engineering and neuroscience as a means to interface the neural system directly to prostheses. Advancing research and applications in this field can assist in successfully restoring motor, sensory, and cognitive functions. Emerging Theory and Practice in Neuroprosthetics brings together the most up-to-date research surrounding neuroprosthetics advances and applications. Presenting several new results, concepts, and further developments in the area of neuroprosthetics, this book is an essential publication for researchers, upper-level students, engineers, and medical practitioners.

How does one ensure information security for a computer that is entangled with the structures and processes of a human brain – and for the human mind that is interconnected with such a device? The need to provide information security for neuroprosthetic devices grows more pressing as increasing numbers of people utilize therapeutic technologies such as cochlear implants, retinal prostheses, robotic prosthetic limbs, and deep brain stimulation devices. Moreover, emerging neuroprosthetic technologies for human enhancement are expected to increasingly transform their human users’ sensory, motor, and cognitive capacities in ways that generate new ‘posthumanized’ sociotechnological realities. In this context, it is essential not only to ensure the information security of such neuroprostheses themselves but – more importantly – to ensure the psychological and physical health, autonomy, and personal identity of the human beings whose cognitive processes are inextricably linked with such devices. InfoSec practitioners must not only guard against threats to the confidentiality and integrity of data stored within a neuroprosthetic device’s internal memory; they must also guard against threats to the confidentiality and integrity of thoughts, memories, and desires existing within the mind the of the device’s human host. This second edition of The Handbook of Information Security for Advanced Neuroprosthetics updates the previous edition’s comprehensive investigation of these issues from both theoretical and practical perspectives. It provides an introduction to the current state of neuroprosthetics and expected future trends in the field, along with an introduction to fundamental principles of information security and an analysis of how they must be re-envisioned to address the unique challenges posed by advanced neuroprosthetics. A two-dimensional cognitional security framework is presented whose security goals are designed to protect a device’s human host in his or her roles as a sapient metavolitional agent, embodied embedded organism, and social and economic actor. Practical consideration is given to information security responsibilities and roles within an organizational context and to the application of preventive, detective, and corrective or compensating security controls to neuroprosthetic devices, their host-device systems, and the larger supersystems in which they operate. Finally, it is shown that while implantable neuroprostheses create new kinds of security vulnerabilities and risks, they may also serve to enhance the information security of some types of human hosts (such as those experiencing certain neurological conditions).