Novel Antibacterial Biomaterials For Medical Applications And Modeling Of Drug Release Process

This book provides a comprehensive review of synthesis and physicochemical and biological characterization of novel antibacterial biomaterials produced according to original procedures and aimed at medical applications such as wound dressing, soft and hard tissue implants, drug delivery devices, and carriers for cell cultivation. It is intended for all researchers working in the fields of biomaterials and biomedical engineering, as well as medical professionals, science and engineering graduate students, academics, and industrial researchers. Includes in-depth discussions on synthesis and physicochemical characterization of novel poly vinyl alcohol-based hydrogels aimed at wound dressings and soft tissue implants Explores synthesis and physicochemical characterization of novel bioceramic hydroxyapatite-based coatings on metal surface aimed for hard tissue implants Reviews cytotoxicity and antibacterial activity of novel poly vinyl alcohol-based hydrogels aimed for wound dressing and soft tissue implants Discusses cytotoxicity and antibacterial activity of bioceramic hydroxyapatite-based coatings on metal surface aimed for hard tissue implants Provides original fractional derivative models of drug release process from hydrogels and bioceramic coatings on metal surface and explores diffusion mechanism

"This book provides a comprehensive review of synthesis and physicochemical and biological characterization of novel antibacterial biomaterials produced according to original procedures and aimed at medical applications such as wound dressing, soft and hard tissue implants, drug delivery devices and carriers for cell cultivation. This book is intended for all researchers working in the fields of biomaterials and biomedical engineering, as well as medical professionals, science and engineering graduate students, academics, and industrial researchers"--

Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance focuses on recent and emerging trends surrounding nanomaterials and nano-drug delivery approaches to combat antimicrobial resistance. The relationship between nanomaterials and antimicrobial activity needs to be deeply explored to meet the challenges of combating antimicrobial resistance. The content of this book is divided into three main topic areas, including (i) how to overcome the existing traditional approaches to combat antimicrobial resistance, (ii) applying multiple drug delivery mechanisms to target multi-drug resistant microbes, and (iii) how nanomaterials can be used as drug carriers. This is an important reference source for those looking to understand how nanotechnology plays an important role in combatting disease and infection. As antimicrobial resistance threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses, and fungi, this is a timely resource. Outlines how to overcome existing traditional approaches to combatting antimicrobial resistance Explains how to apply multiple drug delivery mechanisms (MDR) to the target area in order to better combat antimicrobial resistance Shows how nanomaterials are used as drug carriers in this context

This book presents an experimental and computational account of the applications of biopolymers in the field of medicine. Biopolymers are macromolecules produced by living systems, such as proteins, polypeptides, nucleic acids, and polysaccharides. Their advantages over polymers produced using synthetic chemistry include: diversity, abundance, relatively low cost, and sustainability. This book explains techniques for the production of different biodevices, such as scaffolds, hydrogels, functional nanoparticles, microcapsules, and nanocapsules. Furthermore, developments in nanodrug delivery, gene therapy, and tissue engineering are described.

With the need to combat emerging infectious diseases, research around antimicrobial biomaterials and their applications is booming. This book provides the field with a much-needed fundamental overview of the science, addressing the chemistry of a broad range of biomaterial types, and their applications in the biomedical industry. Materials covered include polymers, from those with inherent antimicrobial activity to those that release antimicrobial agents, antimicrobial ceramics and inorganic compounds, such as metal based antimicrobial additives, and the developing field of biomimetic materials, are discussed. Surfaces, coatings and adhesives are covered, whilst the applications of these antimicrobial materials in biomedical applications, from catheters to orthopaedics, dentistry to ophthalmology, are explored. Edited by international leaders and with contributions from the best in the field, this book is the go-to resource for graduates and researchers in biomaterials science, biomedical engineering, chemical engineering, and materials and polymer chemistry.

Polymeric Biomaterials for Healthcare Applications details a broad range of polymeric biomaterials, methods of synthesis and preparation, and their various applications in healthcare and biomedicine. The book provides a fundamental overview of polymers and processing technologies to allow clinical scientists to explore the use of these polymers in alternative applications. A wide variety of healthcare applications are covered, including treatment for autoimmune diseases and bacterial infections, tissue engineering, gene delivery, wound dressing, and more. The book provides a core introductory text for clinical and materials scientists new to the area of polymeric biomaterials. This book will prove useful to academics and researchers in materials science, biomedical engineering, clinical science and pharmaceutical science. Covers a broad range of polymeric biomaterials, including chitosan, alginate, cellulose, collagen, synthetic conjugates, and more Details a wide variety of healthcare applications for polymeric biomaterials, such as orthopedic engineering, antibiotics, targeted drug delivery, and more Provides a detailed overview of polymer processing technologies and sterilization considerations

Surface bio-contamination has become a severe problem that contributes to outbreaks of community acquired and nosocomial infections through contiguous fomite transmission of diseases. Every year, thousands of patients die due to nosocomial infections by pathogens. It is therefore essential to develop novel strategies to prevent or improve the treatment of biomaterial concomitant infections. The concept of antimicrobial materials is becoming increasingly important not only in the hospital and healthcare environments, but also for laboratories, home appliances, and certain industrial applications. Materials are now being developed to prevent the buildup, spread and transfer of harmful microbes, and to dynamically deactivate them. Drawing on research and examples from around the world, this book highlights the latest advances in, and applications of, antibacterial biomaterials for biomedical devices, and focuses on metals with antibacterial coatings/surfaces, antibacterial stainless steels and other commonly used antibacterial materials. It also discusses the role of innovative approaches and provides a comprehensive overview of cutting-edge research on the processing, properties and technologies involved in the development of antimicrobial applications. Given its scope, the book will be of interest to researchers and policymakers, as well as undergraduate and graduate students of biochemistry, microbiology, and environmental chemistry

This book explores in depth a wide range of functional biomaterials-based systems for drug, gene delivery, and biomedical aspects. The chapters cover newer technologies such as polymeric micelle, pH-responsive biomaterials, stimuli-responsive hydrogels, silk fibroin, inorganic biomaterials, synthetic biomaterials, 3D printed biomaterials, metallic biomaterials, ceramic and hybrid biomaterials. It also describes the theranostic approaches for cancer therapy, the biomaterials-based nanofibers scaffolds in tissue engineering, as well as the strategies applications of metallic biomaterials for the medical and dental prosthetic field. This newer and updated approach will be attractive for biomedical engineering students working on materials science in the development of novel drug delivery strategies. The book will be an important reference for researchers and professionals working on biomaterial research in the pharmaceutical and medical fields.