Novel Formulations And Future Trends

Novel Formulations and Future Trends, Volume Three in the Recent and Future Trends in Pharmaceutics series, explores aspects of pharmaceutics with an original approach focused on technology, novelties and future trends. It discusses the most important developments in drug delivery, including important and exciting areas such as mucosal, implantable, transdermal, gastroretentive, vaccine and targeted drug delivery systems. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. This is an essential reference for researchers in academia and industry as well as advanced graduate students. New technologies are also explored including 3D printing and computational pharmaceutics. Explores the most recent technologies in drug delivery in detail Contains contributions from the leading experts from academia, research, industry and regulatory agencies Includes high quality illustrations, flow charts and tables for easy understanding of concepts Discusses practical examples and research case studies

ADVANCES in NOVEL FORMULATIONS for DRUG DELIVERY The 27 chapters describe novel strategies for drug/nutraceutical delivery and embrace the development of formulations with herbal ingredients, while also highlighting disease therapeutics. Drug delivery technology has witnessed many advancements purported to cater to the customized needs of its ultimate beneficiaries—the patients. Today, dosage forms are not confined to conventional tablets, capsules, or injectables, but have evolved to cover novel drug carriers such as particulates, vesicles, and many others. Nanotechnological advancements have played a major role in this paradigm shift in ways of delivering active pharmaceutical ingredients. A new dimension in the use of food as medicine has also gained prominence in recent years. A portmanteau of nutrition and pharmaceuticals is “nutraceuticals,” also known as functional foods and dietary supplements. The technologies which were earlier included in drug delivery have been attempted for the delivery of nutraceuticals as well. Herbal actives have received increased attention due to their low risk-to-benefit ratio. The field of drug delivery is quite dynamic in nature, as witnessed by its evolution from conventional dosage forms to nanotechnology-assisted drug products. A variety of formulations via different drug delivery routes have been developed to treat/cure/mitigate diseases or disorders. This book, comprising of 27 chapters, is a thorough compilation of information relevant to drug delivery systems with an emphasis on products based on nanotechnology. Audience Researchers, scientists, industry professionals, formulators and product developers, regulatory agencies in a variety of settings including novel drug delivery research laboratories, pharmaceutical, and pharmacy industries, biomedical sciences, food and nutraceuticals manufacturers, and nanotechnology.

Dosage Forms, Formulation Developments and Regulations, Volume One in the Recent and Future Trends in Pharmaceutics series, explores aspects of pharmaceutics, with an original approach focused on technology, novelties and future trends in the field. The book discusses the most recent developments in pharmaceutical preformulation and formulation studies, biopharmaceutics and novel pharmaceutical formulations, regulatory affairs, and good manufacturing practices. Exciting areas such as formulation strategies, optimization techniques, the biopharmaceutical classification system, and pharmaceutical aerosols are included. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day, so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. This is an essential reference for researchers in academia and industry as well as advanced graduate students in pharmaceutics. Examines trends and recent technologies in dosage, formulation and regulation Contains contributions from leading experts in academia, research, industry and regulatory agencies Includes high-quality illustrations, flow charts and tables for easy understanding of concepts Discusses practical examples and research case studies

Handbook of Functional Beverages and Human Health provides potential applications and new developments in functional beverages, nutraceuticals, and health foods. In addition to serving as a reference manual, it summarizes the current state of knowledge in key research areas and contains novel ideas for future research and development. Additionally,

The four-day international Conference on Pest Management in Rice, which is the subject of this volume, was the third in an ongoing series of meetings on tropical crops organised by the Pesticides Group of the Society of Chemical Industry, London. The participants came from both the public and private sectors and from many different countries. All the major groups of pests-weeds, microorganisms, arthropods and rodents-were considered, as the organisers believe that it is necessary to address the total pest management problems in each particular growing area, and the variety of the papers indicates the importance of a multi disciplinary approach to their solution. Rice is one of the most important world crops and is the major source of food for around 60% of the world's population, with a world production of 500 million tonnes from 150 million hectares of land. Since world stocks amount to only two months supply, many people are at risk from famine. Moreover, it has been esti mated that the world requirement in 2020 will be about 760 million tonnes, an increase of 50%. This pressure of population on food makes efficient pest management vital and is the reason for bringing together experts from all over the world to this major conference.

Formulations, Regulations, and Challenges of Nutraceuticals focuses on various novel micro- and nanocarriers being employed in the formulation and delivery of nutraceutical ingredients to increase their efficacy, bioavailability, safety, and stability. It also highlights the current challenges and future strategies for the development of novel nutraceuticals and functional foods with enhanced health benefits. The focus is on the formulations and regulations. As compared to traditional drugs, there are no minimal regulations on nutraceutical products, which make them more market friendly. Since nutraceutical ingredients have no defined regulations at global level, they are not considered as medicine or therapeutic agents. Some countries have devised their own guidelines for regulating the usage of nutraceuticals, either as pharmaceutical ingredients or as food supplements. This volume addresses the need for common regulatory guidelines with important research on the production of stable and efficient nutraceutical formulations. The numerous regulatory frameworks being employed in Asia and European regulatory agencies in commercialization of nutraceutical products produced by manufacturing companies are discussed. Chapters examine the factors affecting the stability of nutraceuticals in food and gut environments by stressing the results generated from in vitro and in vivo studies and suggests good manufacturing practices to be followed for the development of nutraceuticals. Formulations, Regulations, and Challenges of Nutraceuticals will be valuable for upper-level students, faculty, nutraceutical researchers and practitioners, regulatory agencies, and those involved in the production and development of nutraceutical products.

This book offers an authoritative review of biopharmaceuticals and their clinical relevance. Biopharmaceuticals have been showing high therapeutic potential by means of biological and biosimilar medicines, particularly for the treatment of cancer, chronic diseases (e.g. diabetes, Crohn's disease, psoriasis and rheumatoid arthritis), neurodegenerative disorders (e.g. multiple sclerosis), and they have also been contributing to the progress of innovative therapies such as assisted reproductive medicine. Since the eighties, several biopharmaceuticals have been approved and, due to patents expiration, many biosimilars are also marketed. In this book, readers will find the most relevant updated information about the main clinical applications of pharmaceutical biotechnology. The authors provide expert analysis about the industrial challenges of recombinant proteins and the different classes of biopharmaceuticals, including monoclonal antibodies, vaccines, growth factors and stem cells. Topics such as bioprinting technologies in tissue engineering, gene therapy and personalized medicine are also covered in this book. Professionals, students and researchers interested in this field will find this work an important account.

The study of adjuvants substances added to vaccine formulations to increase efficacy is one of the fastest growing disciplines in immunology and vaccine development. This book reviews the state-of-the-art of development of novel adjuvants and the science that supports them. There is an increasing need of novel adjuvants for preventive vaccines targeting infectious diseases for which conventional formulations have failed. New adjuvants are also needed to improve existing vaccines in the elderly, infants and chronically infected individuals that mount a suboptimal immune response. In addition, adjuvants could be very useful for the development of effective therapeutic vaccines against chronic infections and cancer. In this context, the book provides an overview of vaccine adjuvants with a special focus on their composition and mechanism of action.