Open Systems Science

Open systems science is the methodology employed to manage and solve the problems in systems whose operation involves interaction with the outside world, as opposed to being closed and complete within themselves. This new methodology was first announced at the 20th anniversary symposium of Sony CSL in 2008. Falling outside the direct scope of traditional science, an open system usually consists of multiple subsystems with varying numbers, relations and functions. Throughout the last decades, computer scientists, addressing the problems presented by globalization and the massive expansion in the application of new technologies, began to realize that open systems science could provide some of the solutions they were seeking with regard to complex and dependable systems. Starting with a chapter explaining the basic concept of open systems science, this book goes on to present the work of contributors from a variety of different disciplines, who explain how open systems science can be applied to their field. Including topics such as; biological robustness, the application of open systems methods to develop new drugs, the study of language and meaning, the interdisciplinary field of visual computing and user interfaces as the merger between the real and virtual world, this book explores the directions of science and technology in the 21st century and will be of interest to all those involved in the development and operation of complex interactive systems. IOS Press is an international science, technical and medical publisher of high-quality books for academics, scientists, and professionals in all fields. Some of the areas we publish in: -Biomedicine -Oncology -Artificial intelligence -Databases and information systems -Maritime engineering -Nanotechnology -Geoengineering -All aspects of physics -E-governance -E-commerce -The knowledge economy -Urban studies -Arms control -Understanding and responding to terrorism -Medical informatics -Computer Sciences

This pioneering text provides a comprehensive introduction to systems structure, function, and modeling as applied in all fields of science and engineering. Systems understanding is increasingly recognized as a key to a more holistic education and greater problem solving skills, and is also reflected in the trend toward interdisciplinary approaches to research on complex phenomena. While the concepts and components of systems science will continue to be distributed throughout the various disciplines, undergraduate degree programs in systems science are also being developed, including at the authors’ own institutions. However, the subject is approached, systems science as a basis for understanding the components and drivers of phenomena at all scales should be viewed with the same importance as a traditional liberal arts education. Principles of Systems Science contains many graphs, illustrations, side bars, examples, and problems to enhance understanding. From basic principles of organization, complexity, abstract representations, and behavior (dynamics) to deeper aspects such as the relations between information, knowledge, computation, and system control, to higher order aspects such as auto-organization, emergence and evolution, the book provides an integrated perspective on the comprehensive nature of systems. It ends with practical aspects such as systems analysis, computer modeling, and systems engineering that demonstrate how the knowledge of systems can be used to solve problems in the real world. Each chapter is broken into parts beginning with qualitative descriptions that stand alone for students who have taken intermediate algebra. The second part presents quantitative descriptions that are based on pre-calculus and advanced algebra, providing a more formal treatment for students who have the necessary mathematical background. Numerous examples of systems from every realm of life, including the physical and biological sciences, humanities, social sciences, engineering, pre-med and pre-law, are based on the fundamental systems concepts of boundaries, components as subsystems, processes as flows of materials, energy, and messages, work accomplished, functions performed, hierarchical structures, and more. Understanding these basics enables further understanding both of how systems endure and how they may become increasingly complex and exhibit new properties or characteristics. Serves as a textbook for teaching systems fundamentals in any discipline or for use in an introductory course in systems science degree programs Addresses a wide range of audiences with different levels of mathematical sophistication Includes open-ended questions in special boxes intended to stimulate integrated thinking and class discussion Describes numerous examples of systems in science and society Captures the trend towards interdisciplinary research and problem solving

By making use of the principles of systems science, the scientific community can explain many complicated matters of the world and shed new light on unsettled problems. Each real science has its own particular methodology for not only qualitative but also quantitative analyses, so it is important to understand the organic whole of systems research

The subject “Systems sciences and cybernetics” is the outcome of the convergence of a number of trends in a larger current of thought devoted to the growing complexity of (primarily social) objects and arising in response to the need for globalized treatment of such objects. This has been magnified by the proliferation and publication of all manner of quantitative scientific data on such objects, advances in the theories on their inter-relations, the enormous computational capacity provided by IT hardware and software and the critical revisiting of subject-object interaction, not to mention the urgent need to control the efficiency of complex systems, where “efficiency” is understood to mean the ability to find a solution to many social problems, including those posed on a planetary scale. The result has been the forging of a new, academically consolidated scientific trend going by the name of Systems Theory and Cybernetics, with a comprehensive, multi-disciplinary focus and therefore apt for understanding realities still regarded to be inescapably chaotic. This subject entry is subdivided into four sections. The first, an introduction to systemic theories, addresses the historic development of the most commonly used systemic approaches, from new concepts such as the so-called “geometry of thinking” or the systemic treatment of “non-systemic identities” to the taxonomic, entropic, axiological and ethical problems deriving from a general “systemic-cybernetic” conceit. Hence, the focus in this section is on the historic and philosophical aspects of the subject. Moreover, it may be asserted today that, beyond a shadow of a doubt, problems, in particular problems deriving from human interaction but in general any problem regardless of its nature, must be posed from a systemic perspective, for otherwise the obstacles to their solution are insurmountable. Reaching such a perspective requires taking at least the following well-known steps: a) statement of the problem from the determinant variables or phenomena; b) adoption of theoretical models showing the interrelationships among such variables; c) use of the maximum amount of – wherever possible quantitative – information available on each; d) placement of the set of variables in an environment that inevitably pre-determines the problem. That epistemology would explain the substantial development of the systemic-cybernetic approach in recent decades. The articles in the second section deal in particular with the different methodological approaches developed when confronting real problems, from issues that affect humanity as a whole to minor but specific questions arising in human organizations. Certain sub-themes are discussed by the various authors – always from a didactic vantage –, including: problem discovery and diagnosis and development of the respective critical theory; the design of ad hoc strategies and methodologies; the implementation of both qualitative (soft system methodologies) and formal and quantitative (such as the “General System Problem Solver” or the “axiological-operational” perspective) approaches; cross-disciplinary integration; and suitable methods for broaching psychological, cultural and socio-political dynamisms. The third section is devoted to cybernetics in the present dual meaning of the term: on the one hand, control of the effectiveness of communication and actions, and on the other, the processes of self-production of knowledge through reflection and the relationship between the observing subject and the observed object when the latter is also observer and the former observed. Known as “second order cybernetics”, this provides an avenue for rethinking the validity of knowledge, such as for instance when viewed through what is known as “bipolar feedback”: processes through which interactions create novelty, complexity and diversity. Finally, the fourth section centres around artificial and computational intelligence, addressing sub-themes such as “neural networks”, the “simulated annealing” that ranges from statistical thermodynamics to combinatory problem-solving, such as in the explanation of the role of adaptive systems, or when discussing the relationship between biological and computational intelligence.

This book describes how to achieve dependability in information systems. The author first proposes viewing systems as open systems instead of closed systems and presents Open Systems Dependability as a property for a system that has the ability to provide optimal services, minimize damage when stoppages occur, resume services quickly, and achieve a

As we approach the end of the 20th century we can look back upon the achievements that have been made in a variety of human endeavours with pride. Enormous strides have been made to improve the quality of life of millions of people through the application of the scientific discoveries made during this and past centuries. The 20th century will be remembered as much for the mass exploitation of scientific discovery as for the discoveries themselves. The technological age has meant that the human being is able to contemplate activities which "defy" nature. For example, some of the work involved in the preparation of these proceedings has been done whilst travelling at over 500 miles per hour seven miles above the surface of the earth. It is not difficult to conjecture about the effect that this relatively recent technology has had upon a number of "systems". Air transportation has provided a number of benefits including such disparate examples such as enabling holidays, famine relief and the cross fertilisation of cultural practices from other lands. Equally, there have been undesirable effects such as enabling the means of mass destruction, interference in other cultures and the speedy transportation of disease. Moreover, the physical presence of the aeroplane itself represents the consumption of fossil fuels, a source of pollution and a change in the way think about life. The view expressed here is of course the view of an inhabitant of the "western world".

Complex Systems Science in Biomedicine Thomas S. Deisboeck and J. Yasha Kresh Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts. In Parts I & II, Complex Systems Science in Biomedicine provides a general systems thinking perspective and presents some of the fundamental theoretical underpinnings of this rapidly emerging field. Part III then follows with a multi-scaled approach, spanning from the molecular to macroscopic level, exemplified by studying such diverse areas as molecular networks and developmental processes, the immune and nervous systems, the heart, cancer and multi-organ failure. The volume concludes with Part IV that addresses methods and techniques driven in design and development by this new understanding of biomedical science. Key Topics Include: • Historic Perspectives of General Systems Thinking • Fundamental Methods and Techniques for Studying Complex Dynamical Systems • Applications from Molecular Networks to Disease Processes • Enabling Technologies for Exploration of Systems in the Life Sciences Complex Systems Science in Biomedicine is essential reading for experimental, theoretical, and interdisciplinary scientists working in the biomedical research field interested in a comprehensive overview of this rapidly emerging field. About the Editors: Thomas S. Deisboeck is currently Assistant Professor of Radiology at Massachusetts General Hospital and Harvard Medical School in Boston. An expert in interdisciplinary cancer modeling, Dr. Deisboeck is Director of the Complex Biosystems Modeling Laboratory which is part of the Harvard-MIT Martinos Center for Biomedical Imaging. J. Yasha Kresh is currently Professor of Cardiothoracic Surgery and Research Director, Professor of Medicine and Director of Cardiovascular Biophysics at the Drexel University College of Medicine. An expert in dynamical systems, he holds appointments in the School of Biomedical Engineering and Health Systems, Dept. of Mechanical Engineering and Molecular Pathobiology Program. Prof. Kresh is Fellow of the American College of Cardiology, American Heart Association, Biomedical Engineering Society, American Institute for Medical and Biological Engineering.

This book has a rather strange history. It began in Spring 1989, thirteen years after our Systems Science Department at SUNY -Binghamton was established, when I was asked by a group of students in our doctoral program to have a meeting with them. The spokesman of the group, Cliff Joslyn, opened our meeting by stating its purpose. I can closely paraphrase what he said: "We called this meeting to discuss with you, as Chairman of the Department, a fundamental problem with our systems science curriculum. In general, we consider it a good curriculum: we learn a lot of concepts, principles, and methodological tools, mathematical, computational, heuristic, which are fundamental to understanding and dealing with systems. And, yet, we learn virtually nothing about systems science itself. What is systems science? What are its historical roots? What are its aims? Where does it stand and where is it likely to go? These are pressing questions to us. After all, aren't we supposed to carry the systems science flag after we graduate from this program? We feel that a broad introductory course to systems science is urgently needed in the curriculum. Do you agree with this assessment?" The answer was obvious and, yet, not easy to give: "I agree, of course, but I do not see how the situation could be alleviated in the foreseeable future.