Optical Fiber Biosensors

Optical Fiber Biosensors: Device Platforms, Biorecognition, Applications provides a comprehensive overview of the field of fiber optic sensors using an interdisciplinary approach that covers the fabrication of sensing devices and optical hardware, the functionalization to perform selective biorecognition, and the main applications of biosensors, with a present and a future outlook. Chapters discuss the principles of light propagation and the sensing devices suitable to perform biosensing with optical fibers, the process to functionalize the previous devices to selective biosensing, and applications in cells, small molecules, biomarkers and protein sensing, with a birds eye view on the most important results. This book provides a coherent picture of fiber optic biosensors, from the start (the device) to the end (the application), explaining in simple terms what is the whole process for development of a biosensor. The book also contains practical material (e.g. commercial instruments, fabrication instructions, medical standards for biocompatibility) that cannot be easily found elsewhere, and this is very useful for researchers to plan their development and build their labs. Covers the technologies and operating principles of optical fiber devices used in biosensing Contains chapters on the chemistry and operational strategy to functionalize a fiber device to become an effective biosensor Addresses the main applications of fiber optic biosensors and their specialization

This book discusses the history, physics, fundamental principles, sensing technologies, and characterization of plasmonic phenomenon-based fiber-optic biosensors, using optic-plasmonic sensors as a case study. It describes the plasmonic phenomenon and its application in optical fiber-based sensing, presented based on properties and usage of different nanomaterials spread across nine chapters. Content covers advances in nanomaterials, structural designing, and their scope in biomedical applications. Future developments of biosensing devices and related articulate methods are also described. Features: Gives a comprehensive view on the nanomaterials used in plasmonic optical fiber biosensors Includes synthesis, characterization, and usage for detection of different analytes Discusses trends in the design of wavelength-based optical fiber sensors Reviews micro- and nanostructured biosensing devices Explores application of plasmonic sensors in the biosensing field This book is aimed at researchers and graduate students in Optical Communications, Biomedical Engineering, Optics, Sensors, Instrumentation, and Measurement.

Optical Biosensors, 2ed describes the principles of successful systems, examples of applications, and evaluates the advantages and deficiencies of each. It also addresses future developments on two levels: possible improvements in existing systems and emerging technologies that could provide new capabilities in the future. The book is formatted for ease of use and is therefore suitable for scientists and engineers, students and researcher at all levels in the field. * Comprehensive analysis and review of the underlying principles by optical biosensors * Updates and informs on all the latest developments and hot topic areas * Evaluates current methods showing the advantages and disadvantages of various systems involved

PART I. Optical Biosensors: The Present -- Chapter 1. Optrode-based Fiber Optic Biosensors -- Israel Biran and David R. Walt -- Chapter 2. Evanescent Wave Fiber Optic Biosensors -- Chris Rowe Taitt and Frances S. Ligler -- Chapter 3. Planar Waveguides for Fluorescence Biosensors -- Kim Sapsford, Chris Rowe Taitt, and Frances S. Ligler -- Chapter 4. Flow Immnosensor -- Anne W. Kusterbeck -- Chapter 5. Time Resolved Fluorescence -- Richard Thompson -- Chapter 6. Electrochemiluminescence -- Mark M. Richter -- Chapter 7. Surface Plasmon Resonance Biosensors -- Jiri Homola, Sinclair Yee, and David Myszka -- Chapter 8. The Resonant Mirror Optical Biosensor -- Tim Kinning and Paul Edwards -- Chapter 9. Interferometric Biosensors -- Daniel P. Campbell and Candice J. McCloskey -- Part II. Optical Biosensors: The Future -- Chapter 10. Genetic Engineering of Signaling Molecules -- Agatha Feltus and Sylvia Daunert -- Chapter 11. Artificial Receptors for Chemosensors -- Thomas W. Bell and Nicholas ...

This authoritative new resource presents fiber optic sensors and their applications in medical device design and biomedical engineering. Readers gain an understanding of which technology to use and adopt, and how to connect technologies with their respective applications. This book explores the innovation of diagnostics and how to use diagnostic tools. Principles of fiber optic sensing are covered and include details about intensity-based sensors, fiber bragg gratings, distributed sensors, and fabry-perot interferometers. This book explores interrogation software, standards for medical sensors, and discusses protocols and tools for validation. Various medical device engineering and applications are examined, including sensor catheterization, cardiovascular sensors, diagnostic in gastroscopy, urology, neurology, sensing in thermal ablation. Applications and detection of SPR sensors are presented, along with minimally invasive robotic surgery, smart textiles, wearable sensors and fiber-optic spectrometric sensors. This is a one-stop reference on fiber optic sensors for biomed applications.

Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems will cover the up-to-date biosensor technologies used for the detection of bacteria. Written by the world's most renowned and learned scientists each in their own area of expertise, Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems is the first title to cover this expanding research field.

This book focuses on a research field that is rapidly emerging as one of the most promising ones for the global optics and photonics community: the “lab-on-fiber” technology. Inspired by the well-established "lab on-a-chip" concept, this new technology essentially envisages novel and highly functionalized devices completely integrated into a single optical fiber for both communication and sensing applications. Based on the R&D experience of some of the world's leading authorities in the fields of optics, photonics, nanotechnology, and material science, this book provides a broad and accurate description of the main developments and achievements in the lab-on-fiber technology roadmap, also highlighting the new perspectives and challenges to be faced. This book is essential for scientists interested in the cutting-edge fiber optic technology, but also for graduate students.