Optical Fiber Based Plasmonic Biosensors

This book discusses the history, physics, fundamental principles, sensing technologies, and characterization of plasmonic phenomenon-based fiber-optic biosensors, using optic-plasmonic sensors as a case study. It describes the plasmonic phenomenon and its application in optical fiber-based sensing, presented based on properties and usage of different nanomaterials spread across nine chapters. Content covers advances in nanomaterials, structural designing, and their scope in biomedical applications. Future developments of biosensing devices and related articulate methods are also described. Features: Gives a comprehensive view on the nanomaterials used in plasmonic optical fiber biosensors Includes synthesis, characterization, and usage for detection of different analytes Discusses trends in the design of wavelength-based optical fiber sensors Reviews micro- and nanostructured biosensing devices Explores application of plasmonic sensors in the biosensing field This book is aimed at researchers and graduate students in Optical Communications, Biomedical Engineering, Optics, Sensors, Instrumentation, and Measurement.

The book provides an introduction of surface plasmons and presents its applications in the sensing of various chemical and biological analyses using optical fiber technology. The field is developed by introducing the surface plasmons for semi-infinite metal–dielectric interface with discussion of their propagation length and penetration depth. Practical issues with the excitation of surface plasmons in different configurations and in various geometries including various means of their excitation have also been included. The book discusses the essential components of fiber optic sensors, their functions and the performance parameters along with the theoretical description of fiber optic Surface Plasmon Resonance (SPR) sensors with respect to various light launching conditions. The fabrication methods and protocols used for the fabrication of the fiber optic SPR chemical and biosensors have been described. Some fiber optic sensing applications based on SPR phenomena and various issues, such as sensitivity enhancement, influence of external stimuli etc, have been an important part of the book. The book will help beginners as well as established researchers in understanding the fundamentals and advancements of optical fiber plasmonic sensor technology. The book contains both the rigorous theory and the experimental techniques of SPR and related variety of sensors. Contents:IntroductionPhysics of PlasmonsCharacteristics and Components of Fiber Optic SensorTheory of SPR-based Optical Fiber SensorFabrication and Functionalization MethodsSPR based Sensing ApplicationsSPR based Fiber Optic Sensors: Factors Affecting PerformanceFuture Scope of ResearchAppendices:Dispersion Relations of Dielectric Materials and MetalsList of Constants Readership: Beginners as well as established researchers who are interested in the fundamentals and advancements of optical fiber plasmonic sensor technology. Key Features:All the contents in this book are totally different from the topics covered in other books on fiber optic sensors as we focus on chemical and biochemical sensing applications of fiber topic plasmonic sensorsThe book discusses the fiber optic chemical and biosensors based on plasmonics which is one of the hottest topics of research these days. Further, the book includes sensor fabrication methods apart from just adding sensors based on surface interactionsThe book includes not only the basics of surface plasmons but also the chemical and bio-chemical sensing applications using optical fiber technologyThe book covers the state of art work on fiber optic sensors utilizing surface plasmon resonance techniqueThe authors have carried out tremendous amount of research on this area during the last 10 years and their work has extensively been cited in the literatureKeywords:Optical Fiber;Sensor;Surface Plasmon;Plasmonics

This book provides a comprehensive overview of the photonic sensing field by covering plasmonics, photonic crystal, and SOI techniques from theory to real sensing applications. A literature review of ultra-sensitive photonic sensors, including their design and application in industry, makes this a self-contained and comprehensive resource for different types of sensors, with high value to the biosensor sector in particular. The book is organized into four parts: Part I covers the basic theory of wave propagation, basic principles of sensing, surface plasmon resonance, and silicon photonics; Part II details the computational modeling techniques for the analysis and prediction of photonic sensors; Part III and Part IV cover the various mechanisms and light matter interaction scenarios behind the design of photonic sensors including photonic crystal fiber sensors and SOI sensors. This book is appropriate for academics and researchers specializing in photonic sensors; graduate students in the early and intermediate stages working in the areas of photonics, sensors, biophysics, and biomedical engineering; and to biomedical, environmental, and chemical engineers.

This book provides a thorough vision of the current trends in plasmonic optical fiber biochemical sensing. It gathers the most recent technological information and shows the maturity reached by the different subsequent technologies. Demonstrating roadmaps for the design process and implementation of plasmonic optical fiber biochemical sensors, the book bridges the gap between theory and application. With this philosophy, understanding key physical properties is of paramount importance for the efficient design of sensing platforms that will meet target specifications. You will learn about the role of the fiber configuration and the functional coating on the properties of the resulting optrodes. You will also get an encompassing overview on all optical fiber configurations used for plasmonic sensing thus far, especially on the progress made over the last decade and rendering the technology compatible for use in real conditions. The book presents both fundamental aspects and advanced applications while focusing on recent and emerging fields of research, such as the use of tilted fiber Bragg gratings, the integration of sensors in situ, the use of smart interrogation techniques, and much more. This is a unique reference for both beginners and experts in optical fiber-based sensors, especially for industrial engineers working in biophotonics and biochemical sensing, as it presents state-of-the-art design procedures and sensing features. The book’s theoretical background combined with recent advances of plasmonic-based optical fiber technologies also make it highly beneficial for all researchers, academics, and students specialized or interested in this flourishing and promising discipline.

In this book Andreas Dahlin has written a comprehensive and thorough review of plasmonic biosensors that operate by refractometric detection. After an introductory chapter on biosensors, in which he sets out the concepts of biosensing in its application to such areas as proteomics, medical diagnostics and environmental control, he undertakes an integrated coverage of surface chemistry, surface physics and optics, specifically related to the requirements of design of a plasmonic biosensor. Sections on nanoparticle plasmons and surface plasmons follow, leading to a review of SPR technology for biosensing. The optical properties of nanoholes in metal films and other more complicated plasmonic nanostructures are also briefly discussed. Later chapters discuss experimental plasmon spectroscopy and spectral analysis while the final sections discuss topics such as sensor response and the extent to which quantitative measurements can be made. The book introduces a few relatively controversial opinions on some open questions, such as how best to define sensor performance and the practical use of highly miniaturized sensors. Each of the chapters is extensively referenced and contains appropriate illustrations. The book contains a wealth of information that will be highly beneficial to both existing and new users of refractometric sensing techniques in life science research. It will be a valuable resource for post-graduate research students, academic researchers and those working in industry.

This book provides wide-ranging coverage of current developments in biomedical sensing based on photonic techniques. Biomedical sensing is a dynamic topic that promises to deliver much in the future evolution of medical diagnostics, delivering advanced tools for fundamental research in biology at the micrometre and nanometre scales. The book explores a variety of alternative physical and biological methodologies that have become available for application, such as plasmonic sensors and photonic crystal biosensors. At the same time, it addresses issues that potentially limit the capability of biomedical optical sensing techniques, while reviewing the state-of-the-art in biomedical optical sensing for the future work that will lead to near-universal applications of such techniques. Edited and written by leading experts in this domain, this book is ideal as a comprehensive manual for researchers and graduate students.

This authoritative new resource presents fiber optic sensors and their applications in medical device design and biomedical engineering. Readers gain an understanding of which technology to use and adopt, and how to connect technologies with their respective applications. This book explores the innovation of diagnostics and how to use diagnostic tools. Principles of fiber optic sensing are covered and include details about intensity-based sensors, fiber bragg gratings, distributed sensors, and fabry-perot interferometers. This book explores interrogation software, standards for medical sensors, and discusses protocols and tools for validation. Various medical device engineering and applications are examined, including sensor catheterization, cardiovascular sensors, diagnostic in gastroscopy, urology, neurology, sensing in thermal ablation. Applications and detection of SPR sensors are presented, along with minimally invasive robotic surgery, smart textiles, wearable sensors and fiber-optic spectrometric sensors. This is a one-stop reference on fiber optic sensors for biomed applications.