Oscillation And Stability Of Delay Models In Biology

Environmental variation plays an important role in many biological and ecological dynamical systems. This monograph focuses on the study of oscillation and the stability of delay models occurring in biology. The book presents recent research results on the qualitative behavior of mathematical models under different physical and environmental conditions, covering dynamics including the distribution and consumption of food. Researchers in the fields of mathematical modeling, mathematical biology, and population dynamics will be particularly interested in this material.

In studying the dynamics of populations, whether of animals, plants or cells, it is crucial to allow for delays such as those due to gestation, maturation or transport. This book deals with a fundamental question in the analysis of the effects of delays, namely whether they affect the stability of steady states.

This monograph provides a definitive overview of recent advances in the stability and oscillation of autonomous delay differential equations. Topics include linear and nonlinear delay and integrodifferential equations, which have potential applications to both biological and physical dynamic processes. Chapter 1 deals with an analysis of the dynamical characteristics of the delay logistic equation, and a number of techniques and results relating to stability, oscillation and comparison of scalar delay and integrodifferential equations are presented. Chapter 2 provides a tutorial-style introduction to the study of delay-induced Hopf bifurcation to periodicity and the related computations for the analysis of the stability of bifurcating periodic solutions. Chapter 3 is devoted to local analyses of nonlinear model systems and discusses many methods applicable to linear equations and their perturbations. Chapter 4 considers global convergence to equilibrium states of nonlinear systems, and includes oscillations of nonlinear systems about their equilibria. Qualitative analyses of both competitive and cooperative systems with time delays feature in both Chapters 3 and 4. Finally, Chapter 5 deals with recent developments in models of neutral differential equations and their applications to population dynamics. Each chapter concludes with a number of exercises and the overall exposition recommends this volume as a good supplementary text for graduate courses. For mathematicians whose work involves functional differential equations, and whose interest extends beyond the boundaries of linear stability analysis.

There has been a considerable progress made during the recent past on mathematical techniques for studying dynamical systems that arise in science and engineering. This progress has been, to a large extent, due to our increasing ability to mathematically model physical processes and to analyze and solve them, both analytically and numerically. With its eleven chapters, this book brings together important contributions from renowned international researchers to provide an excellent survey of recent advances in dynamical systems theory and applications. The first section consists of seven chapters that focus on analytical techniques, while the next section is composed of four chapters that center on computational techniques.

An oscillator is dedicated to the generation of signals. It is used in computers, telecoms, watchmaking, astronomy, and metrology. It can be a pendulum, an electronic oscillator based on quartz technology, an optoelectronic oscillator, or an atomic clock, depending on its application. Since water clocks of antiquity, mechanical clocks invented during the thirteenth century, and the discovery of piezoelectricity by Jacques and Pierre Curie in 1880, oscillators have made great progress. This book does not attempt to tell the story of oscillators, but rather provides an overview of particular oscillator structures through examples from mathematics to oscillators, and from the millimeter scale to the vibration of a building, focusing on recent developments, as we live in a time when technology and mathematical analysis play a vital role.

This book provides an introduction to the theory of dynamical systems with the aid of the Mathematica® computer algebra package. The book has a very hands-on approach and takes the reader from basic theory to recently published research material. Emphasized throughout are numerous applications to biology, chemical kinetics, economics, electronics, epidemiology, nonlinear optics, mechanics, population dynamics, and neural networks. Theorems and proofs are kept to a minimum. The first section deals with continuous systems using ordinary differential equations, while the second part is devoted to the study of discrete dynamical systems.

This textbook is for biologists, to conduct quantitative analysis and modeling of biological processes at molecular and cellular levels. Focusing on practical concepts and techniques for everyday research, this text will enable beginners, both students and established biologists, to take the first step in quantitative biology. It also provides step-by-step tutorials to run various sample programs in one’s personal computer using Excel and Python. This volume traces topics, starting with an introductory chapter, such as modeling, construction and execution of numerical models, and key concepts in quantitative biology: feedback regulations, fluctuations and randomness, and statistical analyses. It also provide sample codes with guidance to procedure programming for actual biological processes such as movement of the nucleus within a cell, cell-cycle regulation, stripe pattern formation of skins, and distribution of energy. Written by a leading research scientist who has a background in biology, studied quantitative approaches by himself, and teaches quantitative biology at several universities, this textbook broadens quantitative approaches for biologists who do not have a strong background in mathematics, physics, or computer programming, and helps them progress further in their research.

"This book highlights the use of systems approaches including genomic, cellular, proteomic, metabolomic, bioinformatics, molecular, and biochemical, to address fundamental questions in complex diseases like cancer diabetes but also in ageing"--Provided by publisher.