Pathogenic Viruses and Armamentarium Design

Pathogenic Viruses and Armamentarium Design
Author: Awanish Kumar,Kumud Pant
Publsiher: Elsevier
Total Pages: 0
Release: 2023-06-01
Genre: Science
ISBN: 9780443152429

Download Pathogenic Viruses and Armamentarium Design Book in PDF, Epub and Kindle

Pathogenic Viruses and Armamentarium Design covers the latest developments in viral target elucidation and viral control using wet and dry lab strategies. The control and combat strategies and their implementation compiled in this book are a valuable aid in understanding viral disease progression and designing new strategies against existing and evolving viruses. This important resource is a comprehensive compilation of anti-viral approaches designed and devised using computational and other laboratory techniques. The content targets the readership of college students, scientists and research investigators working on the pathogenic virus and development of prophylactics and therapeutics against viral infection. Researchers from biotechnology, infection biology, chemistry and pharmaceutical science will surely benefit from this content. The incorporation of software and tools will also help both experienced and new bioinformaticians and students. Covers the latest developments in viral target elucidation and viral control using wet and dry lab strategies Presents a comprehensive compilation of anti-viral approaches designed and devised using computational and other laboratory techniques Provides a valuable aid in understanding viral disease progression and designing new strategies against existing and evolving viruses

Adenoviral Vectors for Gene Therapy

Adenoviral Vectors for Gene Therapy
Author: David T. Curiel
Publsiher: Academic Press
Total Pages: 868
Release: 2016-03-10
Genre: Science
ISBN: 9780128005101

Download Adenoviral Vectors for Gene Therapy Book in PDF, Epub and Kindle

Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors. Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement Demonstrates noninvasive imaging of adenovirus-mediated gene transfer Discusses utility of adenoviral vectors in animal disease models Considers Federal Drug Administration regulations for human clinical trials

Global Health Impacts of Vector Borne Diseases

Global Health Impacts of Vector Borne Diseases
Author: National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Forum on Microbial Threats
Publsiher: National Academies Press
Total Pages: 397
Release: 2016-10-21
Genre: Medical
ISBN: 9780309377591

Download Global Health Impacts of Vector Borne Diseases Book in PDF, Epub and Kindle

Pathogens transmitted among humans, animals, or plants by insects and arthropod vectors have been responsible for significant morbidity and mortality throughout recorded history. Such vector-borne diseases â€" including malaria, dengue, yellow fever, and plague â€" together accounted for more human disease and death in the 17th through early 20th centuries than all other causes combined. Over the past three decades, previously controlled vector-borne diseases have resurged or reemerged in new geographic locations, and several newly identified pathogens and vectors have triggered disease outbreaks in plants and animals, including humans. Domestic and international capabilities to detect, identify, and effectively respond to vector-borne diseases are limited. Few vaccines have been developed against vector-borne pathogens. At the same time, drug resistance has developed in vector-borne pathogens while their vectors are increasingly resistant to insecticide controls. Furthermore, the ranks of scientists trained to conduct research in key fields including medical entomology, vector ecology, and tropical medicine have dwindled, threatening prospects for addressing vector-borne diseases now and in the future. In June 2007, as these circumstances became alarmingly apparent, the Forum on Microbial Threats hosted a workshop to explore the dynamic relationships among host, pathogen(s), vector(s), and ecosystems that characterize vector-borne diseases. Revisiting this topic in September 2014, the Forum organized a workshop to examine trends and patterns in the incidence and prevalence of vector-borne diseases in an increasingly interconnected and ecologically disturbed world, as well as recent developments to meet these dynamic threats. Participants examined the emergence and global movement of vector-borne diseases, research priorities for understanding their biology and ecology, and global preparedness for and progress toward their prevention, control, and mitigation. This report summarizes the presentations and discussions from the workshop.

Emerging and Reemerging Viral Pathogens

Emerging and Reemerging Viral Pathogens
Author: Moulay Mustapha Ennaji
Publsiher: Academic Press
Total Pages: 388
Release: 2019-09-14
Genre: Science
ISBN: 9780128149676

Download Emerging and Reemerging Viral Pathogens Book in PDF, Epub and Kindle

Emerging and Reemerging Viral Pathogens: Applied Virology Approaches Related to Human, Animal and Environmental Pathogens, Volume Two presents new research information on viruses and their impact on the scientific community. It provides a reference book on certain viruses in humans, animals and vegetal, along with a comprehensive discussion on interspecies interactions. The book then looks at the drug, vaccine and bioinformatical strategies that can be used against these viruses, giving the reader a clear understanding of transmission. The book's end goal is to create awareness that the appearance of newly transmissible pathogens is a global risk that requires shared/adoptable policies for prevention and control. Covers most emerging viral disease in humans, animals and plants Provides the most advanced tools and techniques in molecular virology and the modeling of viruses Creates awareness that the appearance of new transmissible pathogens is a global risk Highlights the need to adopt shared policies for the prevention and control of infectious diseases

HIV Molecular Biology and Pathogenesis Viral Mechanisms

HIV  Molecular Biology and Pathogenesis  Viral Mechanisms
Author: Anonim
Publsiher: Academic Press
Total Pages: 524
Release: 2000-09-07
Genre: Science
ISBN: 9780080553924

Download HIV Molecular Biology and Pathogenesis Viral Mechanisms Book in PDF, Epub and Kindle

The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines.The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia. Detailed insights into viral packaging, expression, and assembly Mechanistic understanding of how HIV interacts with receptors and infects cells Delineation of virally encoded regulatory processes unique to HIV Clinical Applications: An updated review of current chemotherapeutics for HIV New concepts in the discovery and design of novel anti-HIV drugs The latest developments in HIV-vaccine research

Vaccine Design

Vaccine Design
Author: Michael F. Powell,Mark J. Newman
Publsiher: Springer
Total Pages: 977
Release: 2012-12-06
Genre: Medical
ISBN: 9781461518235

Download Vaccine Design Book in PDF, Epub and Kindle

When my interest was first drawn to the phenomenon of vaccination for virus diseases in the late 1930s, the state of the art and the science of vaccine design was not far advanced beyond the time of Jenner at the end of the 18th century and of Pasteur a century later. In the 1930s it was still believed that for the induction of immunity to a virus-caused disease the experience of infection was required, but not for a toxin-caused disease such as diphtheria or tetanus, for which a chemically detoxified antigen was effective for immu nization. This prompted the question as to whether it might be possible to produce a similar effect for virus diseases using nonreplicating antigens. When in the 1930s and 1940s it was found possible to propagate influenza viruses in the chick embryo, protective effects could be induced without the need to experience infection by the use of a sufficient dose of a noninfectious influenza virus preparation. Later in the 1940s, it became possible to propagate polio and other viruses in cultures of human and monkey tissue and to immunize against other virus diseases in the same way. Later, with the advent of the era of molecular biology and genetic engineering, antigens and vaccines could be produced in new and creative ways, using either replicating or nonreplicating forms of the appropriate antigens for inducing a dose-related protective state.

Fighting Infection in the 21st Century

Fighting Infection in the 21st Century
Author: P. W. Andrew,G. L. Smith,D. E. S. Stewart-Tull,P. Oyston
Publsiher: John Wiley & Sons
Total Pages: 287
Release: 2008-04-30
Genre: Science
ISBN: 9780470695203

Download Fighting Infection in the 21st Century Book in PDF, Epub and Kindle

The 20th century has seen improvements in both public health and disease prevention which, in turn, have had a dramatic impact on our lives. Success in preventing infection by vaccination and treating infection with antibiotics led some to believe that infectious disease was a thing of the past. However, the adaptability of pathogens and the emergence of new diseases has presented microbiologists with a fresh set of challenges as we enter the new millennium. While celebrating past successes and highlighting developing problems, this volume aims to address some of the issues facing microbiologists in the future. Covering a wide range of topics, it will provide an invaluable resource for microbiologists and an excellent reference for advanced students.

The Micro organisms of the Human Mouth

The Micro organisms of the Human Mouth
Author: Willoughby Dayton Miller
Publsiher: Unknown
Total Pages: 406
Release: 1890
Genre: Mouth
ISBN: UCSF:31378008333695

Download The Micro organisms of the Human Mouth Book in PDF, Epub and Kindle