Personalized and Stratified Therapy in Epilepsy

Personalized and Stratified Therapy in Epilepsy
Author: Sara Eyal,Dana Ekstein
Publsiher: Academic Press
Total Pages: 0
Release: 2022-09-15
Genre: Medical
ISBN: 0128173467

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Personalized and Stratified Therapy in Epilepsy highlights the individualized- and subgroup-based approaches in diagnosing, treating, and monitoring epilepsy. Whereas the term 'personalized medicine' is used to describe the focus on individual patients, 'stratified medicine' refers to the definition of population subgroups based on estimates of their differences in the etiology and prognosis of epilepsy, or response to treatment. The book describes the various aspects of personalized and stratified approaches in epilepsy, the potential of these approaches to improve the cost-effectiveness of epilepsy treatment, and barriers to their implementation. The book assists clinicians in rationally choosing the required diagnostic and treatment means for their patients, out of the abundance of available technologies and products. By doing so, they will provide better care, mitigating adverse events, expediting the reach of effective treatment, and reducing costs. The target audience is anyone involved in developing and delivering diagnostic means and treatment for people with epilepsy, including epileptologists, other neurologists, neurosurgeons, pharmacists, nurses, technicians, geneticists, researchers Comprehensively describes individualized and stratified treatment approaches in epilepsy Assists clinicians with rationally choosing the required diagnostic and treatment means for their patients Diagnosis, drugs, non-pharmacological treatments, and future research are all discussed in depth

Textbook of Personalized Medicine

Textbook of Personalized Medicine
Author: Kewal K. Jain
Publsiher: Springer Nature
Total Pages: 744
Release: 2020-12-05
Genre: Medical
ISBN: 9783030620806

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This book is for personalized medicine as a prescription of specific treatments and therapeutics best suited for an individual and considers genetic as well as environmental factors that influence responses to therapy. Best approaches are described for integration of all available technologies for optimizing the therapy of individual patients. This comprehensive third edition covers the latest advances in personalized medicine and several chapters are devoted to various specialties, particulary cancer which is the largest area of application. The book discusses the development of personalized medicine and various players in it such as companies, academic institutions, the government, and the public as the consumer of healthcare. Additionally, the roles of bioinformatics, electronic health records, and digital technologies for personalized medicine are discussed. Textbook of Personalized Medicine, 3rd Edition serves as a convenient source of information for students at many levels and in a wide range of fields, including physicians, scientists, and decision makers in the biopharmaceutical and healthcare industries.

Oxford Textbook of Epilepsy and Epileptic Seizures

Oxford Textbook of Epilepsy and Epileptic Seizures
Author: Samden Lhatoo
Publsiher: Oxford University Press
Total Pages: 395
Release: 2013
Genre: Medical
ISBN: 9780199659043

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Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this volume covers the scientific basis, clinical diagnosis, and treatment of epilepsy and epileptic seizures, and is complemented by an online edition.

The New Era of Precision Medicine

The New Era of Precision Medicine
Author: Mohamad Bydon
Publsiher: Elsevier
Total Pages: 272
Release: 2023-11-24
Genre: Science
ISBN: 9780443139642

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The New Era of Precision Medicine: What it Means for Patients and the Future of Healthcare highlights aspects of precision medicine in different specialties and offers an understanding of how a biological background integrates into clinical guidelines, the therapeutic efficacy of interventions and disease prevention. The book explains how precision healthcare differs among countries, as well as how there is a collaboration among many labs to share resources and knowledge to advance the field across the globe. The book also discusses the cultural differences and cultural sensitivity that may be involved in the precision medicine approach. Finally, with regard to safety and quality outcomes, the book presents a range of current and possible future concerns related to those outcomes. Precision medicine is the new standard of quality healthcare delivery. It aims to optimize patient safety and clinical outcomes, enhance the efficacy of therapeutic interventions, and facilitate disease prevention, offering a way to customize patient care, decision-making, and clinical practice. Highlights the characteristics of precision medicine in different areas Offers an understanding of how a biological background integrates into clinical guidelines, the therapeutic efficacy of interventions, and disease prevention Emphasizes how medicine has transformed from a “one-size-fits-all approach to personalized medicine influenced by individual characteristics Introduces complex topics delivered in terms that target a broad range of audiences

Precision Medicine and Artificial Intelligence

Precision Medicine and Artificial Intelligence
Author: Michael Mahler
Publsiher: Academic Press
Total Pages: 300
Release: 2021-03-12
Genre: Science
ISBN: 9780323854320

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Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions Provides background, milestone and examples of precision medicine Outlines the paradigm shift towards precision medicine driven by value-based systems Discusses future applications of precision medicine research using AI Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine

The Right Therapy for Neurological Disorders

The Right Therapy for Neurological Disorders
Author: Ettore Beghi,G. Logroscino,J. Bogousslavsky
Publsiher: Karger Medical Scientific
Total Pages: 0
Release: 2016
Genre: Nervous system
ISBN: 3318058645

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Most neurological disorders are chronic and aging-related. With the increase of life expectancy their incidence and prevalence will grow in the decades to come, which in turn will increase the load on medical and social systems worldwide. There is thus a desperate need for successful preventive and therapeutic measures based on randomized clinical trials (RTCs) conducted by independent organizations. This book provides a compendium relating most of the principles of reliable RTCs to specific neurological diseases. Contributed by specialized neurologists, the articles touch on important aspects of RCTs with a clear critical approach, highlighting their limitations as well as giving recommendations for their planning and conducting to address the variable genotypic and phenotypic aspects of neurological conditions. Consideration is also given to combining the clinical impact of the study results with patients' values and the interests of pharmaceutical companies. Neurologists involved in clinical trials will certainly benefit from this book, which should become a basic text for all neurological courses dealing with evidence-based neurology.

Treating Nonepileptic Seizures

Treating Nonepileptic Seizures
Author: W. Curt LaFrance,Jeffrey Peter Wincze
Publsiher: Treatments That Work
Total Pages: 193
Release: 2015
Genre: Medical
ISBN: 9780199307173

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The primary aim of Treating Nonepileptic Seizures: Therapist Guide is to equip physicians, psychologists, therapists, nurses, and other practitioners with a validated, step-by-step treatment for psychogenic nonepileptic seizures (NES) that can improve the lives of patients with this disabling disorder. Patients with NES frequently present in neurology, psychiatry, psychology, and emergency departments. The disorder has been documented in the medical literature for centuries, and much is known about the phenomenology, seizure characteristics, psychiatric comorbidities, neuropsychological testing, and psychosocial aspects in NES. However, until recently, much less was known about the effective treatments of patients with psychogenic NES. This intervention provides guidance for clinicians in treating patients with NES and is designed to be used in conjunction with the patient workbook, Taking Control of Your Seizures. Session by session, the Workbook facilitates communication between treatment providers and individual patients with seizures. The authors' clinical experience with epilepsy and NES and research in developing the treatment approach for seizures directly informed the treatment model described. Many patients treated with the intervention have demonstrated improvements in seizures, symptoms, and quality of life.

Seizures and Epilepsy

Seizures and Epilepsy
Author: Jerome Engel Jr
Publsiher: Oxford University Press
Total Pages: 737
Release: 2013-01-31
Genre: Medical
ISBN: 9780195328547

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This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.