Physics Of Thermal Therapy

The field of thermal therapy has been growing tenaciously in the last few decades. The application of heat to living tissues, from mild hyperthermia to high-temperature thermal ablation, has produced a host of well-documented genetic, cellular, and physiological responses that are being researched intensely for medical applications, particularly fo

Hyperthermia has been found to be of great benefit in combination with radiation therapy or chemotherapy in the management of patients with difficult and com plicated tumor problems. It has been demonstrated to increase the efficacy, of ionising radiation when used locally but also has been of help in combination with systemic chemotherapy where hyperthermia is carried out to the total body. Problems remain with regard to maximizing the effects of hyperthermia as in fluenced by blood flow, heat loss, etc. The present volume defines the current knowledge relative to hyperthermia with radiation therapy and/or chemotherapy, giving a comprehensive overview of its use in cancer management. Philadelphia/Hamburg, June 1995 L.W. BRADY H.-P. HEILMANN Preface In an attempt to overcome tumor resistance, hypoxia, or unfavorable tumor condi tions, oncological research has come to focus on gene therapy, immunotherapy, new cytotoxic agents, and increasingly sophisticated radiotherapy. Radiation research has been directed towards heavy particle therapy and modification of the radiation response by either protecting or sensitizing agents. Improved dose localization using rotational or conformal strategies has also been implemented. Recently, changes in radiation fractionation schedules have shown promise of better results. Hyperthermia in cancer therapy can be viewed similarly as another means to increase the sensitivity of tumors to radio- and chemotherapy.

The basic physics, the biophysics, the physiological response and the mechanism by which it is obtained, as well as empirical clinical indications and the available evaluation of efficacy, are reviewed for all the heating modalities and the different techniques of application of cold. For students of physical therapy and undergraduate medical students. Annotation copyrighted by Book News, Inc., Portland, OR

This third volume in the series "Hyperthermia and Oncology" provides insight in and updated information on various aspects of interstitial hyperthermia. It aims to serve as a guide for clinicians who are either already working in the field or who wish to implement this treatment.

Electromagnetic Waves-Based Cancer Diagnosis and Therapy: Principles and Applications of Nanomaterials is a reference solution for radiation-based methods in cancer therapy that benefit from nanosystems. The book gives foundational knowledge and the latest techniques across the electromagnetic wave spectrum. It assesses the advantages and limitations of nanosystems in therapy, providing researchers and specialists with the insight to leverage novel nanostructures for therapy and to improve the efficacy of existing methods. It presents a comprehensive reference on the use of nanosystems in radiation-based cancer therapy. What makes this book unique is its coverage of the electromagnetic wave spectrum. Six chapters cover radio-wave-involved cancer therapy and imaging; cancer therapy by microwaves hypothermia; infra-red waves in cancer theranostics; the use of visible light in diagnosis; X-ray based treatments; and gamma ray-involved therapy and imaging. This book offers researchers and specialists a comprehensive overview of radiation-based methods using nanosystems. It will be of great use to researchers and specialists in cancer diagnosis who want to take advantage of novel nanostructures and to improve the performance of conventional methods in radiation-based cancer diagnosis and therapy. Provides a comprehensive reference of radiation-based methods in cancer therapy benefiting from nanosystems Presents advantages and limitations in the use of nanosystems for radiation-based methods in cancer therapy Helps researchers and specialists leverage the potential of novel nanostructures for therapy Offers ways to improve the performance of conventical methods using nanosystems, making this a one-stop solution to the use of nanosystems in radiation-based cancer therapy

In the 1960s a firm rationale was developed for using raised temperatures to treat malignant disease and there has been a continuous expansion of the field ever since. However, a major limitation exists in our ability to heat human tumours, especially those sited deep in the body, with a reasonable degree of temperature uniformity. This problem has resulted in engineers and physicists collaborating closely with biologists and clinicians towards the common goal of developing and testing the clinical potential of this exciting treatment modality. The aim of the physicist and engineer is to develop acceptible methods of heating tumQur masses in as many sites as possible to therapeutic temperatures avoiding excessive heating of normal structures and, at the same time, obtaining the temperature distribution throughout the heated volume. The problem is magnified by both the theoretical and technical limitations of heating methods and devices. Moreover, the modelling of external deposition of energy in tissue and knowledge of tissue perfusion are ill-defined. To this must be added the conceptual difficulty of defining a thermal dose. The NATO course was designed to provide a basis for the integration of physics and technology relevant to the development of hyperthermia. There were 48 lectures covering the theoretical and practical aspects of system design and assessment, including, as far as possible, all the techniques of current interest and importance in the field.

The 41st Annual International Conference of the IEEE EMBS, took place between July 23 and 27, 2019, in Berlin, Germany. The focus was on "Biomedical engineering ranging from wellness to intensive care." This conference provided an opportunity for researchers from academia and industry to discuss a variety of topics relevant to EMBS and hosted the 4th Annual Invited Session on Computational Human Models. At this session, a bevy of research related to the development of human phantoms was presented, together with a substantial variety of practical applications explored through simulation.

This volume emphasizes the science underlying the various phototherapy procedures, which encompasses aspects of classical and molecular photophysics, biological photochemistry, photobiology and biophotonics. Suitable as an introductory reference or textbook.