Physiology Of The Fetal And Neonatal Lung

L. B. STRANG The past 25 years have seen a remarkable growth in our knowledge of lung development in its structural, physiological and biochemical dimensions. Much of the impetus for research leading to new knowledge has derived from the perception that many respiratory disorders in the newborn infant are due to defective development or maladaption of some component or components of the respiratory system. Thus, to cite one example, surfac tant deficiency is clearly seen to be the cause of atelectasis in hyaline mem brane disease; and to cite another, it is widely accepted that the mechanisms controlling patency of the ductus arteriosus and pulmonary vascular resistance also determine the right-to-Ieft or left-to-right shunting frequently observed in the course of neonatal respiratory disorders. There are, however, areas of physiological knowledge - such as those relating to respiratory control and to liquid formation and absorption - which are clearly of great relevance to lung adaptation at birth but where it has not yet proved possible to link a specific clinical state to the malfunction of a particular mechanism. In planning this symposium an attempt was made to organize the material in an orderly manner, starting with the embryonic and fetal stages of growth and development, continuing with respiratory control and the role of surfactant in lung aeration at birth, and ending with the treatment of neonatal respiratory disorders.

This, the second in the Fetus and Neonate series, concentrates on breathing. The book is divided into sections on physiology, pathophysiology and clinical applications. Recent research and concepts about fetal breathing, the transitions at birth and the control of post-natal breathing are reviewed. The roles of pathophysiological processes in the aetiology of respiratory diseases are discussed and important new developments in diagnosis and treatment are reviewed. The book is written by international authorities in the field, who are active researchers in clinical and basic science as well as practitioners in this area of medicine. It will serve as a valuable source of information for those involved in research in perinatal breathing, or training in paediatrics, neonatology and obstetrics. It will also stimulate the interest of a wider range of health care professionals concerned with keeping abreast of new ideas in this important area of medicine.

A text in English and French that includes proceedings of the international conference held in Paris (France), 20-29 January 1985.

Here's today's most encyclopedic, in-depth compendium of knowledge on the normal and abnormal physiology of the fetus and neonate. Over 270 international authorities detail the unique characteristics that distinguish fetal and neonatal physiology from the physiology of adults-and, where appropriate, address the pathophysiology and clinical management of selected neonatal diseases.

Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. You'll also have easy access to the complete contents and illustrations online at expertconsult.com. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease. Access the complete contents and illustrations online at expertconsult.com - fully searchable! Get the latest developments and a full understanding of the distinct physiology of the fetus and newborn so you can treat and manage sick newborns and preemies.

Provide the best care possible with expert insight and clinically relevant coverage of the physiologic changes that occur throughout all major periods of the perinatal experience — prenatal, intrapartum, postpartum, and neonatal. Maternal, Fetal & Neonatal Physiology: A Clinical Perspective, 4th Edition gives you a solid foundation for assessment and therapeutic interventions, featuring an emphasis on the evolving interrelationships between mother, fetus, and neonate and adaptations of preterm and term infants to the extrauterine environment. Solid coverage of the physiologic bases for assessment and therapeutic interventions make this an ideal resource for advanced practice. Synthesis of the latest research studies and evidence-based practice provides vital data on normal physiologic changes during the antepartum, intrapartum and postpartum periods; anatomic and functional development of the fetus; and developmental physiology of preterm and term neonates. Pharmacology tables offer quick access to key pharmacology information and drug effects with clinical examples. Coverage of pathophysiology and interventions for the pregnant woman, fetus, and newborn for selected abnormal events provides a solid understanding of physiologic adaptations and developmental physiology relating to major body systems and metabolic processes. Comprehensive tables, diagrams, and illustrations highlight important concepts and summarize key information Thoroughly updated content offers the very latest evidence-based information, contemporary research, and clinical developments related to maternal, fetal, and neonatal physiology. New coverage on the late pre-term infant provides the most current practice guidelines to promote quality care. Expanded discussions of reproductive processes reflect cutting-edge research and the clinical implications of physiologic and genetic effects brought to bear from both the female and the male. Extensive and reliable web sources allow for further study or checking for updated information. New NICHD standard definitions on fetal monitoring enable you to identify fetal heart rate patterns using standardized nomenclature.

Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease.