Placebo

The biological power of the placebo effect. The power of placebos to ameliorate symptoms has been with us for centuries. Western medicine today is finding it increasingly difficult to ignore the efficacy of placebos. In some clinical trials with placebos as controls, inert or sham replicas of active pharmaceutical drugs and even sham surgeries have been found to be as beneficial as the intervention being tested. In this volume in the MIT Press Essential Knowledge series, Kathryn Hall examines the power of placebos, showing how their effects can influence our clinical trials, clinical encounters and, collectively, Hall argues, our public health. Hall, who has studied the placebo effect for years, reviews the history of the placebo in medicine, tracing its evolution from quackery and patent medicine to its use as a control in clinical trials. She considers the ways that expectations and learning affect our response to placebos; advances in neuroimaging that reveal the inner workings of the placebo effect; the “nocebo” effect; placebo controls in randomized clinical trials; and the use of psychological profiles and genetics to predict individual placebo response. The effects of placebos have been hiding in plain sight; with this book, Hall helps bring them into clearer view.

This book provides a perspective on the concepts placebo and placebo effects, which has been missing so far: a detailed analysis of the history of the terms, their current use, suggested alternatives and the implications of the conceptual confusion. Everybody knows something about placebos and placebo effects. If, however, people are asked to define the concepts, the spectrum becomes wide. Does 'placebo' refer to an inert treatment or does it cover all elements of the patient-physician-interaction except for pharmacological or other physiological mechanisms? Furthermore, if, by definition, a placebo has no effect, what sense does it make to talk about a 'placebo effect'? Even in scientific literature the concepts ‘placebo’ and ‘placebo effect’ are used in many senses and often in a confusing way. While this book discusses many issues which keep puzzling physicians, it also covers the historical developments of the concepts of placebo and placebo effect as well as the conceptual confusion in the definitions. This book is intended for physicians, philosophers, psychologists and any other people interested in placebos, placebo effects and the physician-patient relationship.

Due to the recent explosion of placebo research at many levels the Editors believe that a volume on Placebo would be a good addition to the Handbook of Experimental Pharmacology series. In particular, this volume will be built up on a meeting on Placebo which will be held in Tuebingen (Germany) in January 2013, and where the most prominent researchers in this field will present and exchange their ideas. The authors who will be invited to write chapters for this volume will be the very same speakers at this meeting, thus guaranteeing high standard and excellence in the topic that will be treated. The approach of the book is mainly pharmacological, including basic research and clinical trials, and the contents range from different medical conditions and systems, such as pain and the immune system, to different experimental approaches, like in vivo receptor binding and pharmacological/behavioral conditioning. Overall, the volume will give an idea of modern placebo research, of timely concepts in both experimental and clinical pharmacology, as well as of modern methods and tools in neuroscience.

Is it possible to heal by thought alone—without drugs or surgery? The truth is that it happens more often than you might expect. In You Are the Placebo, best-selling author, international speaker, chiropractor, and renowned researcher of epigenetics, quantum physics, & neuroscience, Dr. Joe Dispenza shares numerous documented cases of those who reversed cancer, heart disease, depression, crippling arthritis, and even the tremors of Parkinson’s disease by believing in a placebo. Similarly, Dr. Joe tells of how others have gotten sick and even died the victims of a hex or voodoo curse—or after being misdiagnosed with a fatal illness. Belief can be so strong that pharmaceutical companies use double- and triple-blind randomized studies to try to exclude the power of the mind over the body when evaluating new drugs. “In his paradigm-altering book, You Are the Placebo, Dr. Joe Dispenza catapults us beyond thinking of the placebo effect as an anomaly. Through 12 concise chapters that read like a true-life scientific thriller, Dispenza gives us rock-solid reasons to accept the game-changer of our lives: that the placebo effect is actually us, proving to ourselves the greatest possibilities of healing, miracles, and longevity! I love this book and look forward to a world where the secret of the placebo is the foundation of everyday life.” — Gregg Braden, New York Times best-selling author of Deep Truth and The Divine Matrix Chapters Include: Foreward by Dawson Church, Ph.D. Part I. Is It Possible? A Brief History of the Placebo The Placebo Effect in the Brain The Placebo Effect in the Body How Thoughts Change the Brain and the Body Suggestibility Attitudes, Beliefs, and Perceptions The Quantum Mind Three Stories of Personal Transformation Information to Transformation: Proof That You Are the Placebo Part II: Transformation Meditation Preparation Changing Beliefs and Perceptions Meditation Becoming Supernatural Dr. Joe does more than simply explore the history and the physiology of the placebo effect. He asks the question: "Is it possible to teach the principles of the placebo, and without relying on any external substance, produce the same internal changes in a person’s health and ultimately in his or her life?" Then he shares scientific evidence (including color brain scans) of amazing healings from his workshops, in which participants learn his consciousness shifting model of personal transformation, based on practical applications of the so-called placebo effect. The book ends with a "how-to" calming meditation for changing limiting beliefs and mental perceptions that hold us back—the first step in healing. You Are the Placebo combines the latest research in neuroscience, biology, psychology, hypnosis, behavioral conditioning, and quantum physics to demystify the workings of the placebo effect . . . and show how the seemingly impossible can become possible. “I discovered that if I could teach people the scientific model of transformation (bringing in a little quantum physics to help them understand the science of possibility); combine it with the latest information in neuroscience, neuroendocrinology, epigenetics, and psychoneuroimmunology; give them the right kind of instruction; and provide the opportunity to apply that information, then they would experience a transformation... This book is about: empowering you to realize that you have all the biological and neurological machinery to do exactly that. My goal is to demystify these concepts with the new science of the way things really are so that it is within the reach of more people to change their internal states in order to create positive changes in their health and in their external world.” — Dr. Joe Dispenza

The Placebo Effect in Clinical Practice brings together what we know about the mechanisms behind the placebo response, as well as the procedures that promote these responses, in order to provide a focused and concise overview on how current knowledge can be applied in treatment settings.

This is the first book to critically review the mechanisms of placebo effects across all medical conditions, diseases and therapies. It is the definitive text on the placebo effect, and will be essential for researchers and clinicians in all medical specialties.