Principles Of Animal Research For Graduate And Undergraduate Students

Principles of Animal Research is the first publication to offer a broad look at animal research science for a student, early researcher, or technician. Offering guidance for all aspects of the research experience, including the research and development of a thesis, model selection, experimental design, IACUC protocol preparation, and animal husbandry and technical procedural needs, the book is a necessary addition to every student, technician, and researcher’s education. Provides background material for students to understand the broader backdrop against which animal research is undertaken Includes ethical and regulatory information Covers commonly used animal models and the process to choose a model for biomedical research

Practicing chemists face a number of ethical considerations, from issues of attribution of authorship through the potential environmental impact of a new process to the decision to work on chemicals that could be weaponised. By keeping ethical considerations in mind when working, chemists can build their own credibility, contribute to public trust in the chemical sciences and do science that benefits the world. Divided into three parts, methodological aspects, research ethics, and social and environmental implications, Good Chemistry introduces tools and concepts to help chemists recognise the ethical and social dimensions of their own work and act appropriately. Written to support chemistry students in their studies this book includes practice questions and examples of relevant situations to help students engage with the subject and prepare for their professional life in academia, industry, or public service.

Reproduction is the backbone of animal-based food production. The reproductive systems of animals vary and are species-dependent. In this regard, all terrestrial animals perform internal fertilization, whereas aquatic animals perform different reproductive strategies such as internal fertilization without mating, external fertilization, viviparous, oviparous, and parthenogenesis. Today, reproductive biotechnology is an important part of the conservation and propagation of animals. This book addresses several hot topics in the field of reproduction of terrestrial and aquatic animals. Over five sections and eight chapters, this volume examines subjects such as cryopreservation, embryo transfer, avian reproduction, intraovarian gestation, and more.

Notes in the Category C: Reflections on Laboratory Animal Care and Use addresses how to improve laboratory animal care and use, also characterizing the current state of the industry and speculating on its long-term future. It offers analysis from a professional who has spent a lot of time in the trenches, also highlighting new approaches to produce further advances in the field. As the proper care and use of lab animals is critically important to scientists and those who depend on data generated from those animals, this comprehensive book is an ideal resource on the topic. Physicians, patients and their families, consumers, federal and non-profit research funding entities, health advocacy organizations, the FDA, EPA, regulatory approval agencies, and companies that invest billions in R&D to create new diagnostics, drugs, vaccines and medical devices will find this an informative addition for their work. Offers an open dialogue about problems and issues in laboratory animal science Discusses various approaches to making laboratory animal science programs more cost-effective Presents new frameworks for lab animal medicine that may advance better veterinary care and improve informative animal models

The term "biodiversity" or "biological diversity" describes the variety of living beings on Earth encompassing microorganisms, plants, animals, and ecosystems, such as coral reefs, forests, and deserts. In fact, it also represents a wealth of biological resources available to us. Today, instead of exploring and preserving its unmapped biodiversity, mankind has gone away from mother nature, conquering the domain through relentless exploitation. This has resulted in an ecological imbalance and thereby has posed serious threat to biodiversity. Declining biodiversity is, therefore, a concern for countless reasons. Biodiversity’s wealth of genetic information can be conserved by storing biological material from endangered species. Cell lines, gametes, and embryos are preserved so that in case a species becomes extinct or there is a need to increase the population of the species, then cloning and artificial reproductive techniques can be used to revive and reproduce the said species. The present volume discusses the biodiversity of specific animal groups, such as cnidarians and fish, as well as potential risks to and methods for conserving some of them. The following important aspects are addressed: 1. The importance of biodiversity in maintaining ecosystem balance for sustainability 2. The emerging role of biodiversity as a source of important materials, pharmaceuticals, food, and so on as such or through genetic manipulation to meet the contemporary and future challenges 3. The impact of environment degradation on biodiversity and conservation in a changing environment 4. Conventional and emerging biotechnological techniques to conserve biodiversity The book is intended for academics, scientists, and naturalists working in the fields of biology, biochemistry, biophysics, and biomedical sciences.

This book provides a meticulous view on methodological drug discovery and development insights from bench to bedside. The current book threads almost each step encompassing drug the discovery and development of a molecule. The chapters focus on computational modus operandi, pharmacological optimization approaches, modern high-throughput screening methods and in-vitro procedures, role of structural biologists in drug discovery and development, medicinal chemistry approaches for drug design, formulation and drug delivery, in-vivo evaluations of candidate molecules, clinical trial procedures and others. The book also covers specific case studies, regulatory approval proceedings, and industrial view point alongside the aforementioned conceptual layout. And at the same time, the volume integrates medical, biological, medicinal, pharmacological and computational streams, and it is suggested as an ideal guideline to a wide audience including molecular biologists, biochemist, pharmacologists, medicinal chemist, toxicologists, drug discovery and development researchers, and all other students interested in these disciplines.

This volume is the first to present a framework of general principles for animal research ethics together with an analysis of the principles' meaning and moral requirements. This new framework of six moral principles constitutes a more suitable set of moral guidelines than any currently available, including the influential framework presented in the Principles of Humane Experimental Technique published in 1959 by zoologist and psychologist William M. S. Russell and microbiologist Rex L. Burch. While other accounts have presented specific directives to guide the use of animals in research, Tom L. Beauchamp and David DeGrazia here offer a set of general moral principles that are adequate to the task of evaluating biomedical and behavioral research involving animals today. Their comprehensive framework addresses ethical requirements pertaining to societal benefit-a critical consideration in justifying the harming of animals in research-and features a thorough program of animal welfare protection. In doing so, their principles bridge the gap between the concerns of the research community and the animal-protection community. The book is distinctive in featuring commentaries on the framework of principles by eminent figures in animal research ethics from an array of relevant disciplines: veterinary medicine, biomedical research, biology, zoology, comparative psychology, primatology, law, and bioethics. The seven commentators-Larry Carbone, Frans de Waal, Rebecca Dresser, Joseph Garner, Brian Hare, Margaret Landi, and Julian Savulescu-scrutinize Beauchamp and DeGrazia's principles in terms of both their theoretical cogency and practical implications, evaluating their relevance to the medical and scientific professions. The range of ethical issues encompassed in Principles of Animal Research Ethics will be useful to professionals in the biomedical and behavioral sciences and will also appeal to individuals and scholars interested in bioethics, animal ethics, and applied ethics generally.