Pyrazole Preparation And Uses

This book has comprehensively reviewed the latest information on pyrazoles, their preparations and uses. It provides extended ideas on pyrazole and its derivatives including their synthesis, chemistry, structure activity relationship (SAR) and therapeutic applications. The health promoting properties of these pyrazoles are discussed in this book with different therapeutic applications of pyrazole scaffold. Topics related to pyrazole and its analogues as potential anticancer, anti-angiogenesis, antiviral, antioxidative, anti-convulsive, anthelmintic, anti-inflammatory, antidiabetic agents are described in this book in detail. Furthermore, current status and future prospects of pyrazole moiety in drug discovery, importance of it in plant systems, its relevance in neurological drug discovery, its potency as herbicidal and antimicrobial agents have been enumerated through different chapters. In a summary, this book is a valuable resource for research scholars, academics, students, industrialists and subject experts working in the multidisciplinary fields like medicinal chemistry, synthetic chemistry, biochemistry, pharmacology, natural product chemistry and other related areas in the field of pyrazole derivatives drug discovery and research.

Heterocycles are present in the molecular architecture of a wide variety of natural products and compounds with significant biological potency. The numerous heterocycles are employed as significant intermediates in the fields of synthetic organic chemistry, pharmaceuticals, and organic synthesis. This book summarizes the synthesis of different heterocycles using various synthetic methods, including green methods, and applications of heterocycles in various fields.

For more than a century, heterocycles have played a crucial role in the biological and industrial development of society, becoming one of the most researched areas within organic chemistry. The first chapter of Microwave-Induced Synthesis of Aromatic Heterocycles is based on microwave theory, the latest developments in instrumentation technology, and the various microwave technologies used for synthesis. The remainder of the chapters are divided into two sections. Section A deals with the five-membered heterocycles (pyrazoles, isoxazoles, triazoles, oxadiazoles, thiazoles, imidazoles, oxazoles, oxazolines etc.) and in Section B, various six-membered heterocycles (triazines, benzoxazoles, benzimidazoles, benzothiazoles) are presented. Both sections contain a detailed, recent literature review of microwave assisted synthesis and its applicability to various aromatic heterocyclics.

This reference work covers general concepts of anti-viral metabolites, classifications, ethnopharmacology, chemistry, clinical and preclinical studies focusing on different medicinal plants against various types of viral infections. Various plants have been used in medicine since ancient times and are known for their strong therapeutic effects. The book will describe potential antiviral properties of medicinal plants against a diverse group of viruses, and provide an insight to the potential plants possess for broad-spectrum antiviral effects against emerging viral infections. The book aims to target a broad audience including virologists, molecular biologist, microbiologist and scientists working with natural products as well as researchers, students, healthcare experts involved in pharmaceutical and medical field.

Continuing the tradition of providing significant and interesting procedures, Organic Syntheses, Collective Volume XII is a compilation of revised editions of Annual Volumes 85 through 89. The contents of this volume are organized by primarily by reaction type, with the precise classification made according to the bias of the editor, who attempted to ascertain the primary purpose or utility of the procedure.

Pharmaceutical organic chemistry is the main branch of organic chemistry deals with the study of preparation, structure and reactions of organic compounds. As it deals with all the chemical reactions related to life, study of Pharmaceutical organic chemistry is important. Application of Organic chemistry in the development of pharmaceuticals, resulted in evolving Pharmaceutical organic chemistry. Hence studying Organic chemistry and applying this knowledge in Pharmaceutical substances is called as Pharmaceutical organic chemistry. Organic chemistry forms the basis of biochemistry, in which various aspects of health and diseases are studied. The biochemical knowledge is very important for the practice of nutritional, medical and related life sciences. In addition Organic chemistry paved way for the development of medicinal chemistry, Pharmaceutical organic chemistry, bioinformatics, biotechnology, gene therapy, Pharmacology, pathology, chemical engineering, dental science and so on. Organic substances play such a vital role in our daily life that all of us should know about organic chemistry in order to understand the manner how it influence our life process.

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