Radiation Oncology For Pediatric Cns Tumors

This book reviews the principles and applications of radiotherapy in the management of pediatric brain tumors to allow the reader to gain a full appreciation of the major aspects involved in caring for these patients. Individual sections are devoted to basic principles, specific management for the full range of tumor entities, radiotherapy techniques, and potential toxicities and their management. The book is written and edited by world leaders in pediatric radiotherapy, and care has been taken to cover the latest advances in diagnosis and radiotherapy techniques. Pediatric brain tumors represent a diverse group of neoplasms that require carefully planned management for successful definitive treatment. Radiotherapy is one of the fundamental components in treatment for the majority of these vulnerable patients. The optimal radiation therapy approach will depend on multiple factors, including tumor type and location, extent of disease, age of the patient, and other therapies. A thorough understanding of the natural history of the disease, communication with the multidisciplinary team, full knowledge of available radiotherapy techniques, and consideration of potential acute and late toxicities are therefore essential for each patient.

Pediatric CNS Tumors is a detailed review of childhood brain tumors that offers a biologically based perspective on their management. For each tumor type, epidemiology, pathological features, clinical presentation, diagnosis, and treatment are discussed. Particular emphasis is placed on the provision of treatment algorithms that reflect current best practice, and controversies and therapeutic agents under development are also addressed. The closing chapters consider many of the diagnostic and treatment modalities common to all tumors, with special attention to experimental and emerging techniques. This third edition of the book has been thoroughly revised and updated to take into account the latest advances in knowledge and treatment.

Pediatric CNS Tumors is a detailed review of childhood brain tumors with a particular emphasis on providing treatment algorithms for each tumor type. Controversies and current therapeutic agents under development are also discussed. The second edition includes expanded chapters on embryonal tumors, rare tumor types, and supportive care for patients with brain tumors.

Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.

This book presents the most up-to-date and innovative information on the targeting and treatment of a wide range of childhood cancers by means of radiation therapy. Written by global experts in pediatric radiation oncology, it documents in detail the treatment regimens appropriate to each disease, highlighting the recent advances that promise to improve rates of survival and cure. The use of image-guided and intensity-modulated radiation therapy is clearly described, and careful attention is also devoted to the roles of proton therapy, stereotactic radiosurgery, stereotactic fractionated radiosurgery, and modulated arc radiotherapy. Separate chapters address localization and verification procedures and anesthesia; pediatric radiation oncology in the palliative care setting; and aspects that are especially relevant in low- and medium-income countries. Beyond clinical radiation oncology, relevant information is provided on radiation physics. The book concludes by examining future directions in the field.

This book presents the most up-to-date and innovative information on the targeting and treatment of a wide range of childhood cancers by means of radiation therapy. Written by global experts in pediatric radiation oncology, it documents in detail the treatment regimens appropriate to each disease, highlighting the recent advances that promise to improve rates of survival and cure. The use of image-guided and intensity-modulated radiation therapy is clearly described, and careful attention is also devoted to the roles of proton therapy, stereotactic radiosurgery, stereotactic fractionated radiosurgery, and modulated arc radiotherapy. Separate chapters address localization and verification procedures and anesthesia; pediatric radiation oncology in the palliative care setting; and aspects that are especially relevant in low- and medium-income countries. Beyond clinical radiation oncology, relevant information is provided on radiation physics. The book concludes by examining future directions in the field.

The diagnosis of cancer in a child is a devastating finding not only to the parents but often to the child. Even though the situation is relatively easy to accept among adults, it is difficult to accept among children because of their general helpless state. The advances that have been made in the management of a child with cancer in the last 20 years have been dramatic in character. These have occurred not only by virtue ofthe contributions from early diagnosis and more precise staging but also from the contribu tions made by surgery, radiation therapy, and the more widespread utilization of chemotherapy regimens. This volume by J. Robert Cassady sets forth the position of radiation oncology in the management of the child with cancer. Radiation therapy remains an important and significant part of the treatment of this group of diseases. The book presents the basic knowledge with regards to pediatric oncology and how it relates to radiation therapy. It gives a timely overview on the topic and is essential for all radiation oncologists involved in the management of children with cancer. Hamburg/Philadelphia, June 1994 H. -P. HEILMANN LUTHER W. BRADY Preface This book provides a thorough review of the role that radiation therapy currently plays in the management of most childhood tumors. Extensively augmented with figures and tables where appropriate, it also provides a concise review of current diagnostic and therapeutic approaches for major childhood malignancies. Extensive and up-to-date reference lists are an added benefit.

The definitive text and reference on pediatric radiation oncology is now in its thoroughly revised and updated Fourth Edition. This edition features a brand-new section on intensity modulated radiation therapy (IMRT), detailed information on three-dimensional treatment planning, and diagrams showing three-dimensional treatment plans for brain tumors, retinoblastoma, sarcomas, and neuroblastoma. The authors review the most recent clinical trials on management of leukemia, supratentorial and infratentorial brain tumors, retinoblastoma, neuroblastoma, Hodgkin's disease, non-Hodgkin's lymphoma, Ewing's sarcoma, osteosarcoma, rhabdomyosarcoma, and Wilms' tumor. This edition also includes new information on the late effects of cancer treatment and the risk of treatment-induced secondary malignant neoplasms.