Regenerative Rehabilitation

This contributed volume presents the current state of research on regenerative rehabilitation across a broad range of neuro- and musculoskeletal tissues. At its core, the primary goal of regenerative rehabilitation is to restore function after damage to bones, skeletal muscles, cartilage, ligaments/tendons, or tissues of the central and peripheral nervous systems. The authors describe the physiology of these neuro- and musculoskeletal tissue types and their inherent plasticity. The latter quality is what enables these tissues to adapt to mechanical and/or chemical cues to improve functional capacity. As a result, readers will learn how regenerative rehabilitation exploits that quality, to trigger positive changes in tissue function. Combining basic, translational, and clinical aspects of the topic, the book offers a valuable resource for both scientists and clinicians in the regenerative rehabilitation field.

This issue of Physical Medicine and Rehabilitation Clinics of North America will cover regenerative medicine. Rapid advances in stem cell science are opening new avenues for drug discovery and may lead to new uses of stem cells for other musculoskeletal disorders. Artcles to be included are: Evidence-Based Regenerative Prolotherapy and Perineural Injection Approaches; Platelet Rich Plasma; Autologous Conditioned Serum; Stem Cell Considerations for the Clinician; Adipose Derived Stromal Vascular Faction and Stem Cell Use, as well as many others.

For more than 30 years, the highly regarded Secrets Series® has provided students, academics, and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Physical Medicine and Rehabilitation Secrets, 4th Edition, offers practical, up-to-date coverage of the full range of essential topics in this dynamic field. This highly regarded resource features the Secrets’ popular question-and-answer format that also includes lists, tables, weblinks, pearls, memory aids, and an easy-to-read style – making an inquiry, reference, and review quick, easy, and enjoyable. The proven Secrets Series® format gives you the most return for your time – concise, easy to read, engaging, and highly effective. Fully revised and updated, including new information on geriatric rehabilitation, rehabilitation philosophy, vocational rehabilitation, disability rating and impairments, and legislation and reimbursement. New chapters and content include Longitudinal Learning; Regenerative Medicine; Musculoskeletal Ultrasound, PM&R ideology and Disability Awareness & Sensitivity, Organ Transplantation; Spinal Deformity: and more. Top 100 Secrets and Key Points boxes provide a rapid overview of the secrets you must know for success in practice, exams, and teaching sessions. Bulleted lists, mnemonics, and practical tips from global leaders in the field provide a concise overview of important board-relevant content. Portable size makes it easy to carry with you for quick reference or review anywhere, anytime.

This book sheds new light on the complex area of regenerative injections used in sports injuries and musculoskeletal conditions, pursuing an evidenced-based approach. Largely ignoring orthopedic surgery, which would involve arthroscopic procedures and scaffolding as they are practiced mainly by orthopedic surgeons, the book instead focuses on injection-based treatments that are particularly useful in sports medicine and for musculoskeletal pain conditions. Including evidence from systematic reviews, meta-analyses, and randomized controlled trials, the book provides a comprehensive overview of regenerative injections such as dextrose, platelet-rich plasma and stem cell therapy, along with their history and scientific basis. It also includes detailed information on the preparation methods, steps of the procedure, and clinical conditions most likely to benefit from it. Given its scope, the book offers a valuable tool for all medical practitioners whose work involves painful musculoskeletal conditions, e.g. sports medicine physicians, orthopedists and interventional physiatrists, as well as general practitioners.

The book examines recent developments in regenerative medicine and the use of musculoskeletal ultrasound. Musculoskeletal regeneration has become a prominent research topic, no doubt due to the sociological and economic pressures imposed by the current ageing population. The ever expanding role of regenerative medicine and the identification as well as characterization of stem cells have introduced a major paradigm shift in the field of musculoskeletal and sports medicine as well as orthopaedic surgery. Whereas in the past, diseased tissue was replaced with allograft material, current trends in research revolve around regenerating damaged tissue. Specifically, regenerative medicine stands in contrast to the standard treatment modalities which impair the body’s natural abilities to facilitate endogenous repair mechanisms such as anti-inflammatory drugs; or destructive modalities (e.g., radiotherapy, nerve ablation, injections of botulinum toxin) and surgical interventions that permanently alter the functioning of a joint, bone or spine. When compared to other allopathic options (including knee and hip arthroplasty with a 90-day mortality rate of 0.7%), regenerative medicine treatment modalities have a lower incidence of adverse events with a growing body of statistically significant medical literature illustrating both their safety and efficacy. Focusing on the major values of regenerative medicine, this book with its 21 chapters is expected to fill an important void in the current literature. It will take that extra step to guide you in your day to day clinical practice. Featuring contributions from a large international group of leaders in regenerative medicine and musculoskeletal ultrasonography, this book is an authoritative reference for rheumatologists, physiatrists, sonographers, radiologists, physiotherapists and orthopaedic specialists.

In this issue of Veterinary Clinics: Small Animal Practice, guest editor Dr. Molly J. Flaherty brings her considerable expertise to the topic of Rehabilitation Therapy. Top experts cover current and emerging areas of interest, with introductory material for the general practitioner as well as advanced material for the rehabilitation veterinarian. Topics include everything from pain management and manual therapies to more focused areas of special interest, such as rehabilitation therapy in palliative care. Contains 12 practice-oriented topics including veterinary spinal manipulation therapy; shockwave therapy; the role of rehabilitation therapy following regenerative medicine in the canine; rehabilitation of soft tissue injuries in agility patients; therapy exercises for early post-operative orthopedic patients; return-to-work for working dogs; feline osteoarthritis management; and more. Provides in-depth clinical reviews on rehabilitation therapy in small animal practice, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Regenerative medicine offers physicians new tools to help repair damaged tissue, alleviate pain, accelerate healing, and improve function for patients with degenerative conditions or sports injuries. Regenerative Treatments in Sports and Orthopedic Medicine is the first comprehensive book devoted to orthobiologic treatments for orthopedic conditions. Authored by experts in regenerative medicine, this evidence- and experience-based guide is written for clinicians looking to understand and effectively implement these treatments in their practices. Broad yet focused coverage of the scientific underpinnings, regulatory issues, staffing and equipment, nutritional and rehabilitation concerns, and orthobiologic interventions for specific clinical problems make this the ideal procedural reference for anyone working to restore function to athletes or other patients with musculoskeletal pathologies. Key Features Unparallelled coverage of clinical science and practical applications Written by pioneering leaders at the forefront of an emerging standard of care Evidence-based indications for initiating orthobiologic therapies Includes a review of important nomenclature for the novice Covers both Platelet Rich Plasma (PRP) and stem cell procedures A must-read guide for practitioners in academic and private practice settings