Regulatory T Cells In Inflammation
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Regulatory T Cells in Inflammation
Author | : Leonie S. Taams,Arne N. Akbar,Marca H.M. Wauben |
Publsiher | : Springer Science & Business Media |
Total Pages | : 240 |
Release | : 2006-03-30 |
Genre | : Medical |
ISBN | : 9783764373016 |
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Regulatory T-cells are essential components of the immune system, and several different subsets of regulatory T-cells have been described. Considerable regulatory function has been attributed to the CD4+CD25+ T-cell subset. These cells act by suppressing adaptive and possibly innate immune responses thereby maintaining or restoring the balance between immunity and tolerance. The suppressive effects of CD4+CD25+ regulatory T-cells are cell-contact dependent. Recent developments and viewpoints in the field of CD4+CD25+ regulatory T-cells as well as the potential use of regulatory T-cells in immunotherapy of inflammatory diseases are discussed in this volume. By linking data from experimental models with recent findings from the clinic, this book will be of interest to immunologists and other biomedical researchers as well as clinicians interested in the regulation and manipulation of the immune response during inflammatory disease.
Signaling Mechanisms Regulating T Cell Diversity and Function
Author | : Jonathan Soboloff,Dietmar J. Kappes |
Publsiher | : CRC Press |
Total Pages | : 258 |
Release | : 2017-03-27 |
Genre | : Medical |
ISBN | : 9781498705097 |
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T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
Regulatory T Cells in Inflammation
Author | : Leonie S. Taams,Arne N. Akbar,Marca H.M. Wauben |
Publsiher | : Birkhäuser |
Total Pages | : 240 |
Release | : 2009-09-03 |
Genre | : Medical |
ISBN | : 3764390271 |
Download Regulatory T Cells in Inflammation Book in PDF, Epub and Kindle
Regulatory T-cells are essential components of the immune system, and several different subsets of regulatory T-cells have been described. Considerable regulatory function has been attributed to the CD4+CD25+ T-cell subset. These cells act by suppressing adaptive and possibly innate immune responses thereby maintaining or restoring the balance between immunity and tolerance. The suppressive effects of CD4+CD25+ regulatory T-cells are cell-contact dependent. Recent developments and viewpoints in the field of CD4+CD25+ regulatory T-cells as well as the potential use of regulatory T-cells in immunotherapy of inflammatory diseases are discussed in this volume. By linking data from experimental models with recent findings from the clinic, this book will be of interest to immunologists and other biomedical researchers as well as clinicians interested in the regulation and manipulation of the immune response during inflammatory disease.
The role of regulatory T cells in controlling inflammatory responses
Author | : Marco Romano,Joshua Daniel Ooi,Estefania Nova-Lamperti,Thomas Wekerle |
Publsiher | : Frontiers Media SA |
Total Pages | : 175 |
Release | : 2023-04-17 |
Genre | : Medical |
ISBN | : 9782832516416 |
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Regulatory T cells and Autoimmune Diseases
Author | : Mitesh Kumar Dwivedi,DeLisa Fairweather |
Publsiher | : Elsevier |
Total Pages | : 984 |
Release | : 2024-05-24 |
Genre | : Medical |
ISBN | : 9780443139482 |
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Regulatory T cells and Autoimmune Diseases addresses recent findings concerning the role of Tregs in the pathogenesis of autoimmune diseases as well as their therapeutic aspects. In particular, this book deals with the various Treg based mechanisms which can lead to autoimmune diseases and covers the different aspects of linking Tregs with autoimmune mechanisms involved in disease development by discussing animal models and human studies. The book specifically focuses on the Treg based therapeutics and their targets to manage all known autoimmune rheumatic, central nervous system, bowel, liver, thyroid, kidney, myopathic, skin, blood & blood vessel, and eye diseases and aims to provide a must-have reference for designing therapeutic strategies to treat these autoimmune diseases. Additionally, the book covers the vaccines induced effects on functioning of Tregs and development of CAR Tregs therapy for these autoimmune diseases and concludes with current challenges and future prospects of Treg-based therapeutics. It is carefully designed to meet the requirements of both basic and advanced researchers in the area and give new dimensions and insight into the regulatory T cells’ role in autoimmune disease pathogenesis and therapeutic aspects. Brings the reader up-to-date on the mechanisms of regulatory T cells (Tregs) in pathogenesis and therapeutics of all autoimmune diseases known to date Provides explicit color illustrations and comprehensible tables for explaining the mechanistic aspects and emerging information in the field Includes human clinical trials and animal model studies for Tregs in diverse autoimmune diseases for the mitigation of the symptoms of autoimmune diseases Offers scientifically applicable and relevant content for readers of various disciplines, including biomedical sciences, medical microbiology/biotechnology, immunology, and medicine
Eosinophils in Health and Disease
Author | : James J. Lee,Helene F. Rosenberg |
Publsiher | : Academic Press |
Total Pages | : 679 |
Release | : 2012-11-02 |
Genre | : Health & Fitness |
ISBN | : 9780123943859 |
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Eosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance.
T Cell Differentiation and Function in Tissue Inflammation
Author | : Amit Awasthi,Ritobrata Goswami |
Publsiher | : Frontiers Media SA |
Total Pages | : 231 |
Release | : 2020-03-11 |
Genre | : Electronic Book |
ISBN | : 9782889636143 |
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Molecular Biology of The Cell
Author | : Bruce Alberts |
Publsiher | : Unknown |
Total Pages | : 0 |
Release | : 2002 |
Genre | : Cytology |
ISBN | : 0815332181 |
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