Selected Aspects Of Cancer Progression Metastasis Apoptosis And Immune Response
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Selected Aspects of Cancer Progression Metastasis Apoptosis and Immune Response
Author | : Hans E. Kaiser,Aejaz Nasir |
Publsiher | : Springer Science & Business Media |
Total Pages | : 251 |
Release | : 2008-05-20 |
Genre | : Medical |
ISBN | : 9781402067297 |
Download Selected Aspects of Cancer Progression Metastasis Apoptosis and Immune Response Book in PDF, Epub and Kindle
The processes of tumor metastasis, apoptosis and anti-tumor immune response are among the most complex yet rapidly advancing fields in the area of cancer research. This monograph, with its leading authorship, presents a comprehensive coverage of the recent advances in the various key concepts in these fundamental aspects of human cancer. It contains state-of-the-science reviews on invasion, metastasis, angiogenesis, apoptosis and immunologic aspects related to cancer.
Inflammation and Cancer
Author | : Bharat B. Aggarwal,Bokyung Sung,Subash Chandra Gupta |
Publsiher | : Springer |
Total Pages | : 490 |
Release | : 2014-05-12 |
Genre | : Medical |
ISBN | : 9783034808378 |
Download Inflammation and Cancer Book in PDF, Epub and Kindle
This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.
Comparative Oncology
Author | : Alecsandru Ioan Baba,Cornel Cătoi |
Publsiher | : Unknown |
Total Pages | : 787 |
Release | : 2007 |
Genre | : Electronic books |
ISBN | : 9732714573 |
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Apoptosis and Cancer
Author | : Seamus J. Martin |
Publsiher | : S. Karger AG (Switzerland) |
Total Pages | : 0 |
Release | : 1997 |
Genre | : Apoptosis |
ISBN | : 3805565798 |
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The past five years have witnessed an explosion of research efforts in the study of how cells die. This book provides an up-to-date overview of our current knowledge of apoptosis and how discoveries in this area impact on our understanding of cancer. By synthesizing many of the recent developments in this area and placing them in perspective, it fulfills an important need. All the contributions are written by experts in their respective fields. The first two chapters give a basic introduction to the cell death machinery and its role in tumor development and progression; subsequent chapters cover current aspects of apoptosis research, including the involvement of cell cycle-related proteins (e.g. cyclin-dependent kinases) in apoptosis, the role of Bcl-2, Bcr-Abl, Rb, p53 and myc in the regulation of cell death, and apoptosis in the context of specific neoplasms such as cancer of the prostate, kidney, leukemia and neuroblastoma. It is also discussed how insights into the regulation of apoptosis may be exploited for designing new drugs aimed at eliminating malignant cells. Compiling the most recent research results on the relationship between apoptosis and cancer in one handy volume, this book will provide a valuable reference for scientists working in cancer research as well as newcomers to the field.
Essentials of Glycobiology
Author | : Ajit Varki,Maarten J. Chrispeels |
Publsiher | : CSHL Press |
Total Pages | : 694 |
Release | : 1999 |
Genre | : Medical |
ISBN | : 0879696818 |
Download Essentials of Glycobiology Book in PDF, Epub and Kindle
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Metastatic Cancer Clinical and Biological Perspectives
Author | : Rahul Jandial |
Publsiher | : CRC Press |
Total Pages | : 312 |
Release | : 2013-08-08 |
Genre | : Medical |
ISBN | : 1587066599 |
Download Metastatic Cancer Clinical and Biological Perspectives Book in PDF, Epub and Kindle
Most cancer deaths are a result of metastasis. The spread of a primary tumor to colonize neighboring and distant organs is the relentless endgame that defines the neoplastic process. Patients who have been diagnosed with cancer are treated to prevent both the recurrence of the tumor at the site of origin and metastasis that would re-stage them as advanced stage IV cancer. Historically and still with some types of cancer, stage IV is perceived by patients as “terminal.” Fortunately, recent molecular therapies have extended the lives of patients with advanced cancer and reassuringly people living with metastatic disease increasingly visit our clinics. What is the path forward? Given that the consilience of science and medicine is a dynamic art from which therapies arise, it would be misguided to consider any single work adequate at capturing the horizon for research. So with humility we constructed this text as primer for scientists. It begins with a broad introduction to the clinical management of common cancers. This is intended to serve as a foundation for investigators to consider when developing basic science hypotheses. Unquestionably, medical and surgical care of cancer patients reveals biology and dictates how novel therapeutics will ultimately be evaluated in clinical trials. The second section of this text offers provocative and evolving insights that underscore the breadth of science involved in the elucidation of cancer metastasis biology. The text concludes with information that integrates scientific and clinical foundations to highlight translational research. This book serves as a framework for scientists to conceptualize clinical and translational knowledge on the complexity of disease that is metastatic cancer.
Signal Transduction in Cancer
Author | : David A. Frank |
Publsiher | : Springer Science & Business Media |
Total Pages | : 358 |
Release | : 2002-12-31 |
Genre | : Medical |
ISBN | : 9781402073403 |
Download Signal Transduction in Cancer Book in PDF, Epub and Kindle
One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."
Crossroads between Innate and Adaptive Immunity
Author | : Peter D. Katsikis,Bali Pulendran,Stephen P. Schoenberger |
Publsiher | : Springer Science & Business Media |
Total Pages | : 232 |
Release | : 2007-12-08 |
Genre | : Medical |
ISBN | : 9780387348148 |
Download Crossroads between Innate and Adaptive Immunity Book in PDF, Epub and Kindle
This compilation presents mini-reviews derived from work presented at the Aegean Conference: "First Crossroads between Innate and Adaptive Immunity," which occurred in October, 2005 at the Hilton Conference Center on the island of Rhodes, Greece. The conference included sessions dedicated to host recognition of and response to pathogens, innate immune networks, antigen presentation, and adaptive immune responses, each headlined by a leading scientist.