Smart Nanomaterials For Infectious Diseases

The book focuses on how sustainable nanomaterials can help with various aspects of infectious diseases, including prevention, diagnosis, and treatment, as well as the characteristics that materials should possess in order to enter clinical trials.

Smart Nanomaterials to Combat the Spread of Viral Infections comprises nanotechnology-based approaches with detailed preventive and treatment methodology for enabling their application in antiviral systems. This book discusses the role of metal nanoparticles in the treatment of and prevention of viral infections and nanotechnology advancements in antiviral coatings to combat affected surfaces. It also covers the use of nanomaterials for the efficient intracellular delivery of antiviral agents to disinfect and treat viral infections. This is a timely coverage of how nanotechnologies and materials as well as the utilization of artificial intelligence and Internet of things–based smart nano-systems are used to control and manage viral infections during the COVID-19 pandemic. Advances in smart research and future antimicrobial applications round out the book. This book provides a comprehensive overview of smart nanomaterials and advanced nano-system applications to researchers and academics in virology, microbiology, chemistry, material science, nanotechnology, and biotechnology as well as those in industries interested in their virucidal properties to prevent viral infections. Encompasses the novel synthesis of nanostructures and cost-effective nanosystems from functional hybrid materials with special emphasis on their effective virucidal properties being biocompatible and economic Examines mechanisms of advanced nanomaterials as effective virucidal agents in disinfectants, coatings, treatment, and preventive approaches Discusses possible advancements and upcoming smart research in antimicrobial applications Offers timely coverage of SARS-CoV-2 pandemic management strategies

This book highlights the recent advancement in point-of-care testing (POCT) technologies utilizing ‘smart’ nanomaterials for the analysis of biomarkers related to disease, which includes metabolites, enzymes, proteins, nucleic acids, cancer cells and multidrug-resistant pathogen. The POCT refers to medical diagnostic tests performed near the place and time of patient care. During the recent pandemic of COVID-19, many realized the importance of affordable, rapid and accurate POCT devices and their usefulness to combat the spread of the infection. The chapters in this book describe the emergence of ‘smart’ nanomaterials with unique physical and chemical properties being utilized in POCT devices for immobilizing biorecognition elements and labels for signal generation, transduction and amplification. It showcases the applications of these smart nanomaterials and their superiority in developing point-of-care diagnostics devices in a wide range of applied fields like food industry, agriculture sector, water quality assessment, pharmaceuticals and tissue engineering. It also looks into the challenges associated and future direction of research in this promising field. This book caters as reference book for researches from the field of nanobiotechnology and biomedical sciences who are interested in the development of rapid, affordable and accurate POCT devices.

Nanotheranostics for Treatment and Diagnosis of Infectious Diseases comprises the latest information on the technological advancements made in the field of nanotechnology for application in therapeutics with diagnostic applications. The book focuses on the theranostic applications of nanomaterials in infectious diseases, highlighting that rapid diagnosis, safe and effective treatment and strong preventive measures like vaccines are urgently needed. It compiles all relevant information to help scientists, researchers and students understand the role of nanomaterials, how nanomaterials could be explored simultaneously for therapeutic and diagnostic applications, and how to ensure safety and efficacy of these nanomaterials. Sections cover fundamental concepts, emerging concerns and challenges to combat infectious diseases, the characterization of nanomaterials for theranostic applications, and the toxicity, biocompatibility and regulatory perspectives in the diagnosis and treatment of infectious diseases. Compiles the latest information on the technological advancements made in the field of nanotechnology for applications in therapeutics Prepares researchers to get ready to fight any emergency which may arise due to the advent of infectious diseases Focuses on the theranostic applications of nanomaterials in infectious diseases Compiles all relevant information to help scientists, researchers and students in understanding the role of nanomaterials and how they could be explored for therapeutic and diagnostic applications

With the start of 2020, the wrath of pandemic challenged the scientific community to develop more advanced drug delivery approaches for biomedical applications, endowing conventional drugs with additional therapeutic benefits and minimum side effects. Although significant advancements have been done in the field of drug delivery, there is a need to focus towards strategizing novel and improved drug delivery systems that should be convenient and cost-effective to the patients, and simultaneously they should also provide financial benefits to pharmaceutical companies. Controlled drug delivery technology offers ample opportunities and scope for improvising the therapeutic efficacy of drugs via optimizing the drug release rate and time. For this endeavour, smart nanomaterials have served as remarkable candidates for biomedical applications, owing to their ground-breaking properties and design. The development of such nanomaterials requires a broad knowledge related to their physio-chemical properties, molecular structure, mechanisms by which the nanomaterials interact with the cells, and methods by which drugs are released at the site of action. This knowledge must also be allied with the knowledge of signaling crosstalk mechanisms that are modulated by the nanomaterial-drugs composite. It can be anticipated that these emerging drug delivery technologies can facilitate the world to successfully encounter such pandemic outbursts in the future in a cost-effective and time-effective manner. The chapters in this book deal with the advanced technologies and approaches that can benefit advanced students, researchers, and industry experts in developing smart and intelligent nanomaterials for future biomedical applications, and development, manufacturing, and commercialization for controlled and targeted drug delivery.

Nanomaterials in Diagnostic Tools and Devices provides a complete overview of the significance of nanomaterials in fabricating selective and performance enhanced nanodevices. It is an interdisciplinary reference that includes contributing subjects from nanomaterials, biosensors, materials science, biomedical instrumentation and medicinal chemistry. This book is authored by experts in the field of nanomaterial synthesis, modeling, and biosensor applications, and provides insight to readers working in various science fields on the latest advancements in smart and miniaturized nanodevices. These devices enable convenient real-time diagnosis of diseases at clinics rather than laboratories, and include implantable devices that cause less irritation and have improved functionality. Research in the field of nanomaterials is growing rapidly, creating a significant impact across different science disciplines and nanotechnology industries. This synthesis and modeling of nanomaterials has led to many technology breakthroughs and applications, especially in medical science. Provides a distinctive platform for the latest trends in the synthesis of smart nanomaterials for nanodevices in disease diagnostics Presents a broad range of advancements and applications of lateral-flow nanostrip for point-of-care applications Examines smart-phone based nanodevices for field-based diagnosis with accurate information Comprises more than 70 figures and illustrations that will help readers visualize and easily understand the role of nanodevices in the field of nanomedicine Serves as an ideal reference for those studying smart nanomaterials, biosensors, and nanodevices for real-time and in-situ clinical diagnosis and drug delivery

The book showcases the newest research on smart nanoplatforms responding to “hypoxia”; an omnipresent pathological feature of many modern-day diseases and its potential applications. The book demonstrates the versatility of hypoxia targeted smart nanoplatforms in disease management in diverse pathological settings presented in chapters contributed by various experts in the field. The themes in the book touch upon critical facets to address pathological hypoxia such as nanomaterials enhancing oxygenation, hypoxia responsive nanoformulations which deliver the drug directly to the hypoxic site, limited toxicity and enhanced efficacy of smart nanoformulations to counter molecular consequences of hypoxia, and theranostics combining hypoxia detection systems with drug delivery systems. This book disseminates the current implications of smart nanomaterials in disease management that can be exploited by scholars, researchers, and pharma industries to develop, manufacture, and commercialize hypoxia targeted diagnostics and therapeutics.

Smart nanomaterials are the basis of diverse emerging applications, and this book covers their technological advances, innovations, and practical applications. It covers advances in the most critical aspects in chemistry and material fabrication of nanomaterials including engineering/prospective applications. The application of smart nanomaterials in the biomedical field, agriculture, food industry, and apparel industry is covered with practical examples. It discusses the future of smart nanomaterials and the pros and cons associated with smart nanomaterials in a detailed manner. Features: Reviews synthesis methods, characterization techniques, and applications of smart nanomaterials. Explores the significance of using smart nanomaterials in futuristic life including examples. Covers bionsensor sensitivity, selectivity, and stability for long-term operation and nanotechnology technique for possibly detecting hazardous viruses. Provides the manufacturing advantages, energy and electronic advantages, medical benefits, environmental effects, and economic issues. Explains risk assessment on humans in detail. This book is aimed at researchers and graduate students in nanomaterials and materials science.