Smart Nanomaterials In Biomedical Applications

With the start of 2020, the wrath of pandemic challenged the scientific community to develop more advanced drug delivery approaches for biomedical applications, endowing conventional drugs with additional therapeutic benefits and minimum side effects. Although significant advancements have been done in the field of drug delivery, there is a need to focus towards strategizing novel and improved drug delivery systems that should be convenient and cost-effective to the patients, and simultaneously they should also provide financial benefits to pharmaceutical companies. Controlled drug delivery technology offers ample opportunities and scope for improvising the therapeutic efficacy of drugs via optimizing the drug release rate and time. For this endeavour, smart nanomaterials have served as remarkable candidates for biomedical applications, owing to their ground-breaking properties and design. The development of such nanomaterials requires a broad knowledge related to their physio-chemical properties, molecular structure, mechanisms by which the nanomaterials interact with the cells, and methods by which drugs are released at the site of action. This knowledge must also be allied with the knowledge of signaling crosstalk mechanisms that are modulated by the nanomaterial-drugs composite. It can be anticipated that these emerging drug delivery technologies can facilitate the world to successfully encounter such pandemic outbursts in the future in a cost-effective and time-effective manner. The chapters in this book deal with the advanced technologies and approaches that can benefit advanced students, researchers, and industry experts in developing smart and intelligent nanomaterials for future biomedical applications, and development, manufacturing, and commercialization for controlled and targeted drug delivery.

Smart nanomaterials are the basis of diverse emerging applications, and this book covers their technological advances, innovations, and practical applications. It covers advances in the most critical aspects in chemistry and material fabrication of nanomaterials including engineering/prospective applications. The application of smart nanomaterials in the biomedical field, agriculture, food industry, and apparel industry is covered with practical examples. It discusses the future of smart nanomaterials and the pros and cons associated with smart nanomaterials in a detailed manner. Features: Reviews synthesis methods, characterization techniques, and applications of smart nanomaterials. Explores the significance of using smart nanomaterials in futuristic life including examples. Covers bionsensor sensitivity, selectivity, and stability for long-term operation and nanotechnology technique for possibly detecting hazardous viruses. Provides the manufacturing advantages, energy and electronic advantages, medical benefits, environmental effects, and economic issues. Explains risk assessment on humans in detail. This book is aimed at researchers and graduate students in nanomaterials and materials science.

Intelligent Nanomaterials for Drug Delivery Applications discusses intelligent nanomaterials with a particular focus on commercial and premarket tools. The book looks at the applications of intelligent nanomaterials within the field of medicine and discusses their future role. This includes the use of intelligent nanomaterials for drugs used in cardiovascular and cancer treatments and examines the promising market of nanoparticles for biomedical and biosensing applications. This resource will be of great interest to scientists and researchers involved in multiple disciplines, including micro- and nano-engineering, bionanotechnology, biomedical engineering, and nanomedicine, as well as pharmaceutical and biomedical industries. Focuses on applications of intelligent nanomaterials within the field of medicine and discusses their role in the future Discusses intelligent nanomaterials, with a particular focus on commercial and premarket tools Examines the promising market of nanoparticles for biomedical and biosensing applications

Smart Nanoparticles for Biomedicine explores smart nanoparticles that change their structural or functional properties in response to specific external stimuli (electric or magnetic fields, electromagnetic radiation, ultrasound, etc.). Particular attention is given to multifunctional nanostructured materials that are pharmacologically active and that can be actuated by virtue of their magnetic, dielectric, optically-active, redox-active, or piezoelectric properties. This important reference resource will be of great value to readers who want to learn more on how smart nanoparticles can be used to create more effective treatment solutions. Nanotechnology has enabled unprecedented control of the interactions between materials and biological entities, from the microscale, to the molecular level. Nanosurfaces and nanostructures have been used to mimic or interact with biological microenvironments, to support specific biological functions, such as cell adhesion, mobility and differentiation, and in tissue healing. Recently, a new paradigm has been proposed for nanomedicine to exploit the intrinsic properties of nanomaterials as active devices rather than as passive structural units or carriers for medications. Discusses the synthesis, characterization and applications of a new generation of smart nanoparticles for nanomedicine applications Explores the problems relating to the biocompatibility of a range of nanoparticles, outlining potential solutions Describes techniques for manipulating specific classes of nanoparticles for a variety of treatment types

Biomedical Applications of Nanoparticles describes the most interesting and investigated biomedical applications of nanoparticles, emphasizing their therapeutic impact. Progress made in the therapy of severe diseases, such as cancer and difficult infections is strictly correlated to the scientific progress and technological development in the field of materials science. Nanoparticles have numerous therapeutic applications, starting with the design of new drugs, delivery systems, therapeutic materials, and their contribution to the development of preventive strategies. The book highlights the impact of nanoparticles on the therapy of infections, antimicrobial effect and also anti-cancer strategies. Successful examples are given throughout the book, along with analysis in order to improve future outcomes of novel therapies. Highlights the term nanotherapeutics and presents several classifications of nanotherapeutics from different points-of-view Presents the recent progress related to nanotherapeutics in the oral cavity Provides the recent progress in the field of biomedical nanoparticles

This book highlights the wide applications of nanomaterials in healthcare and environmental remediation. Presenting nano-based materials that positively influence the growth and proliferation of cells present in soft and hard tissue and are used for the regeneration bone tissue and/or suppression of cancer cells, it also discusses the natural products that can be incorporated in nanofibers for the treatment of cancer. Further, it describes the use of blending and functionalization to produce chitosan nanofibers for biomedical applications, and reviews the role of plasma-enhanced gold nanoparticles in diagnostics and therapeutics. Lastly, the book also introduces various nanotechnology approaches for the removal of waste metabolites in drinking water, and explores the emerging applications of nanorobotics in medicine. Given its scope, this book is a valuable resource for scientists, clinicians, engineers and researchers aiming to gain a better understanding of the various applications of nanotechnology.

Nanoscale structures and materials have been explored in many biological applications because of their novel and impressive physical and chemical properties. Such properties allow remarkable opportunities to study and interact with complex biological processes. This book analyses the state of the art of piezoelectric nanomaterials and introduces their applications in the biomedical field. Despite their impressive potentials, piezoelectric materials have not yet received significant attention for bio-applications. This book shows that the exploitation of piezoelectric nanoparticles in nanomedicine is possible and realistic, and their impressive physical properties can be useful for several applications, ranging from sensors and transducers for the detection of biomolecules to “sensible” substrates for tissue engineering or cell stimulation.

This book reviews the various applications of nanotechnology in human health. The introductory chapters focus on the classifications, types, synthesis, and characterization of various types of nanomaterials, while subsequent chapters highlight current applications of nanomaterials in the diagnosis and treatment of microbial and viral infections, and also in stem cell biology and regenerative medicine. Further, the book explores the potential role of nanomaterials in connection with neuronal differentiation, neuronal protection, and neurological diseases. It demonstrates the use of nanotechnology to diagnose and treat genetic disorders, as well as endocrine and metabolic syndrome diseases. It also discusses the ethics and the negative impacts of nanomaterials on human health. Lastly, it examines the intellectual property aspects and government regulations associated with the research, design, and commercialization of nanotechnology-based products. Given its scope, it offers a valuable resource for all researchers and professionals working with nanotechnology-based applications in human health.