Statistics And Machine Learning Methods For Ehr Data

The use of Electronic Health Records (EHR)/Electronic Medical Records (EMR) data is becoming more prevalent for research. However, analysis of this type of data has many unique complications due to how they are collected, processed and types of questions that can be answered. This book covers many important topics related to using EHR/EMR data for research including data extraction, cleaning, processing, analysis, inference, and predictions based on many years of practical experience of the authors. The book carefully evaluates and compares the standard statistical models and approaches with those of machine learning and deep learning methods and reports the unbiased comparison results for these methods in predicting clinical outcomes based on the EHR data. Key Features: Written based on hands-on experience of contributors from multidisciplinary EHR research projects, which include methods and approaches from statistics, computing, informatics, data science and clinical/epidemiological domains. Documents the detailed experience on EHR data extraction, cleaning and preparation Provides a broad view of statistical approaches and machine learning prediction models to deal with the challenges and limitations of EHR data. Considers the complete cycle of EHR data analysis. The use of EHR/EMR analysis requires close collaborations between statisticians, informaticians, data scientists and clinical/epidemiological investigators. This book reflects that multidisciplinary perspective.

The use of Electronic Health Records (EHR)/Electronic Medical Records (EMR) data is becoming more prevalent for research. However, analysis of this type of data has many unique complications due to how they are collected, processed and types of questions that can be answered. This book covers many important topics related to using EHR/EMR data for research including data extraction, cleaning, processing, analysis, inference, and predictions based on many years of practical experience of the authors. The book carefully evaluates and compares the standard statistical models and approaches with those of machine learning and deep learning methods and reports the unbiased comparison results for these methods in predicting clinical outcomes based on the EHR data. Key Features: Written based on hands-on experience of contributors from multidisciplinary EHR research projects, which include methods and approaches from statistics, computing, informatics, data science and clinical/epidemiological domains. Documents the detailed experience on EHR data extraction, cleaning and preparation Provides a broad view of statistical approaches and machine learning prediction models to deal with the challenges and limitations of EHR data. Considers the complete cycle of EHR data analysis. The use of EHR/EMR analysis requires close collaborations between statisticians, informaticians, data scientists and clinical/epidemiological investigators. This book reflects that multidisciplinary perspective.

HUMAN-MACHINE INTERFACE The book contains the latest advances in healthcare and presents them in the frame of the Human-Machine Interface (HMI). The Human-Machine Interface (HMI) industry has witnessed the evolution from a simple push button to a modern touch-screen display. HMI is a user interface that allows humans to operate controllers for machines, systems, or instruments. Most medical procedures are improved by HMI systems, from calling an ambulance to ensuring that a patient receives adequate treatment on time. This book describes the scenario of biomedical technologies in the context of the advanced HMI, with a focus on direct brain-computer connection. The book describes several HMI tools and related techniques for analyzing, creating, controlling, and upgrading healthcare delivery systems, and provides details regarding how advancements in technology, particularly HMI, ensure ethical and fair use in patient care. Audience The target audience for this book is medical personnel and policymakers in healthcare and pharmaceutical professionals, as well as engineers and researchers in computer science and artificial intelligence.

This book seeks to promote the exploitation of data science in healthcare systems. The focus is on advancing the automated analytical methods used to extract new knowledge from data for healthcare applications. To do so, the book draws on several interrelated disciplines, including machine learning, big data analytics, statistics, pattern recognition, computer vision, and Semantic Web technologies, and focuses on their direct application to healthcare. Building on three tutorial-like chapters on data science in healthcare, the following eleven chapters highlight success stories on the application of data science in healthcare, where data science and artificial intelligence technologies have proven to be very promising. This book is primarily intended for data scientists involved in the healthcare or medical sector. By reading this book, they will gain essential insights into the modern data science technologies needed to advance innovation for both healthcare businesses and patients. A basic grasp of data science is recommended in order to fully benefit from this book.

At the intersection of computer science and healthcare, data analytics has emerged as a promising tool for solving problems across many healthcare-related disciplines. Supplying a comprehensive overview of recent healthcare analytics research, Healthcare Data Analytics provides a clear understanding of the analytical techniques currently available to solve healthcare problems. The book details novel techniques for acquiring, handling, retrieving, and making best use of healthcare data. It analyzes recent developments in healthcare computing and discusses emerging technologies that can help improve the health and well-being of patients. Written by prominent researchers and experts working in the healthcare domain, the book sheds light on many of the computational challenges in the field of medical informatics. Each chapter in the book is structured as a "survey-style" article discussing the prominent research issues and the advances made on that research topic. The book is divided into three major categories: Healthcare Data Sources and Basic Analytics - details the various healthcare data sources and analytical techniques used in the processing and analysis of such data Advanced Data Analytics for Healthcare - covers advanced analytical methods, including clinical prediction models, temporal pattern mining methods, and visual analytics Applications and Practical Systems for Healthcare - covers the applications of data analytics to pervasive healthcare, fraud detection, and drug discovery along with systems for medical imaging and decision support Computer scientists are usually not trained in domain-specific medical concepts, whereas medical practitioners and researchers have limited exposure to the data analytics area. The contents of this book will help to bring together these diverse communities by carefully and comprehensively discussing the most relevant contributions from each domain.

Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. Highlights different data techniques in healthcare data analysis, including machine learning and data mining Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks Includes applications and case studies across all areas of AI in healthcare data

Machine Learning in Medicine covers the state-of-the-art techniques of machine learning and their applications in the medical field. It presents several computer-aided diagnosis (CAD) systems, which have played an important role in the diagnosis of several diseases in the past decade, e.g., cancer detection, resulting in the development of several successful systems. New developments in machine learning may make it possible in the near future to develop machines that are capable of completely performing tasks that currently cannot be completed without human aid, especially in the medical field. This book covers such machines, including convolutional neural networks (CNNs) with different activation functions for small- to medium-size biomedical datasets, detection of abnormal activities stemming from cognitive decline, thermal dose modelling for thermal ablative cancer treatments, dermatological machine learning clinical decision support systems, artificial intelligence-powered ultrasound for diagnosis, practical challenges with possible solutions for machine learning in medical imaging, epilepsy diagnosis from structural MRI, Alzheimer's disease diagnosis, classification of left ventricular hypertrophy, and intelligent medical language understanding. This book will help to advance scientific research within the broad field of machine learning in the medical field. It focuses on major trends and challenges in this area and presents work aimed at identifying new techniques and their use in biomedical analysis, including extensive references at the end of each chapter.

This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a “data desert” when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients.