Systolic And Diastolic Function Of The Heart

Chapter 22: Crossbridge and Muscle Properties, Energetics, and Pressure-Volume Area -- Chapter 23: Constancy and Variability of Oxygen Costs of Mechanical Energy (PVA) and Contractility (Emax) -- Chapter 24: Tight Coupling between Regional Myocardial Oxygen Consumption and Contractile Function -- Chapter 25: Force-Frequency Relation, Force-Interval Relation, and Mechanical Restitution -- Chapter 26: Elastance-Based Mechanical Restitution Provides Data from the Intact Heart Not Available from Any Other Technique -- Chapter 27: Contractility Indices -- Chapter 28: Searching for Indices of Contractility Is Counterproductive -- Chapter 29: Rapid Contractile Upregulation Rematches Stroke Work to Increased Afterload Independent of Ventricular Geometry, Afterload-Related Coronary Perfusion Pressure Fluctuations and Baseline Contractile State -- Chapter 30: Wall Thickening, Shears, and Cleavage Planes -- Chapter 31: Mechanisms of Large Ventricular Wall Shortening and Thickening -- Chapter 32: Twisting, Torsion, and Other Shears -- Chapter 33: Ventricular Twist and Its Relationship to Pressure Volume and Shortening -- Chapter 34: Differences in Systolic and Diastolic Torsional Deformation of the Left Ventricle -- Chapter 35: Coronary Flow, Systolic Perfusion, and the "Gregg Phenomenon -- Chapter 36: Intramyocardial Hydraulic Regulation of Cardiac Mechanics and Energetics -- Chapter 37: Left Ventricular Afterload and Arterial Coupling -- Indexes -- Author Index -- Affiliation Index -- Subject Index

This reference thoroughly equips you to successfully diagnose and manage even the most complex incidences of diastolic heart failure and their comorbidities. It examines the basic mechanisms of this condition through discussions of both cellular and anatomic causes; guides you through non-invasive techniques for diagnosis, including echocardiography, cardiac CT, and MRI; and provides expert advice on pharmacologic management. Covers the basic mechanisms of diastolic heart problems from both cellular and anatomic perspectives. Chapters covering modalities helpful in assessment of diastolic function such as: echocardiography, cardiac MRI, radionuclide ventriculography, and invasive hemodynamic measurements. Features in-depth assessments of all diagnostic methods for diastolic heart failure, including rationales for their use. Examines contributing conditions that play a role in diastolic heart failure and offers guidance on their management. Offers pharmacologic strategies for multiple problem management.

Heart failure is the biggest killer in the western world, and the prevalence is expected to increase due to aging of the population. Over the past decade there has been an increasing awareness of left ventricular (LV) diastolic dysfunction as a mechanism of congestive heart failure. This book provides the clinician with essential insights into the epidemiology and aetiology of diastolic heart failure, and will enable them to understand how the condition can be diagnosed. Furthermore, the book will provide insights in cardiac function that are needed to perform and interpret the diagnostic tests, and to provide some guides to treatment choices.

One of the most time-consuming tasks in clinical medicine is seeking the opinions of specialist colleagues. There is a pressure not only to make referrals appropriate but also to summarize the case in the language of the specialist. This book explains basic physiologic and pathophysiologic mechanisms of cardiovascular disease in a straightforward manner, gives guidelines as to when referral is appropriate, and, uniquely, explains what the specialist is likely to do. It is ideal for any hospital doctor, generalist, or even senior medical student who may need a cardiology opinion, or for that ma.