The Illusion Of Evidence Based Medicine

An expose of the corruption of medicine by the pharmaceutical industry at every level, from exploiting the vulnerable destitute for drug testing, through manipulation of research data, to disease mongering and promoting drugs that do more harm than good. Authors, Professor Jon Jureidini and Dr Leemon McHenry, made critical contributions to exposing the scientific misconduct in two infamous trials of antidepressants. Ghostwritten publications of these trials were highly influential in prescriptions of paroxetine (Paxil) and citalopram (Celexa) in paediatric and adolescent depression, yet both trials (Glaxo Smith Kline's paroxetine study 329 and Forest Laboratories' citalopram study CIT-MD-18) seriously misrepresented the efficacy and safety data. The Illusion of Evidence-Based Medicine provides a detailed account of these studies and argues that medicine desperately needs to re-evaluate its relationship with the pharmaceutical industry. Without a basis for independent evaluation of the results of randomised, placebo-controlled clinical trials, there can be no confidence in evidence-based medicine. Science demands rigorous, critical examination and especially severe testing of hypotheses to function properly, but this is exactly what is lacking in academic medicine. 'The Illusion of Evidence-Based Medicine is a brilliant expose of the negative influence of the global pharmaceutical industry on the integrity of medicine. Every medical student, doctor and patient should read this account of the ways in which medical evidence is distorted to meet the needs of Big Pharma for profits. Importantly the book points to ways in which medicine's independence can be reclaimed through improved governance and public funding.' - Professor Fran Baum

An exposé of the corruption of medicine by the pharmaceutical industry at every level, from exploiting the vulnerable destitute for drug testing, through manipulation of research data, to disease mongering and promoting drugs that do more harm than good. Authors, Professor Jon Jureidini and Dr Leemon McHenry, made critical contributions to exposing the scientific misconduct in two infamous trials of antidepressants. Ghostwritten publications of these trials were highly influential in prescriptions of paroxetine (Paxil) and citalopram (Celexa) in paediatric and adolescent depression, yet both trials (Glaxo Smith Kline's paroxetine study 329 and Forest Laboratories' citalopram study CIT-MD-18) seriously misrepresented the efficacy and safety data. The Illusion of Evidence-Based Medicine provides a detailed account of these studies and argues that medicine desperately needs to re-evaluate its relationship with the pharmaceutical industry. Without a basis for independent evaluation of the results of randomised, placebo-controlled clinical trials, there can be no confidence in evidence-based medicine. Science demands rigorous, critical examination and especially severe testing of hypotheses to function properly, but this is exactly what is lacking in academic medicine.

An expose of the corruption of medicine by the pharmaceutical industry at every level, from exploiting the vulnerable destitute for drug testing, through manipulation of research data, to disease mongering and promoting drugs that do more harm than good. This is a brilliant expose of the negative influence of the global pharmaceutical industry.

An expose of the corruption of medicine by the pharmaceutical industry at every level, from exploiting the vulnerable destitute for drug testing, through manipulation of research data, to disease mongering and promoting drugs that do more harm than good. Authors, Professor Jon Jureidini and Dr Leemon McHenry, made critical contributions to exposing the scientific misconduct in two infamous trials of antidepressants. Ghostwritten publications of these trials were highly influential in prescriptions of paroxetine (Paxil) and citalopram (Celexa) in paediatric and adolescent depression, yet both trials (Glaxo Smith Kline's paroxetine study 329 and Forest Laboratories' citalopram study CIT-MD-18) seriously misrepresented the efficacy and safety data. The Illusion of Evidence-Based Medicine provides a detailed account of these studies and argues that medicine desperately needs to re-evaluate its relationship with the pharmaceutical industry. Without a basis for independent evaluation of the results of randomised, placebo-controlled clinical trials, there can be no confidence in evidence-based medicine. Science demands rigorous, critical examination and especially severe testing of hypotheses to function properly, but this is exactly what is lacking in academic medicine.

Get a quick, expert overview of the many key facets of today’s otolaryngology practice with this concise, practical resource. Dr. Luke Rudmik and a leading team of experts in the field address high-interest clinical topics in this fast-changing field. Presents an evidence-based, clinical approach to leading topics in otolaryngology. Covers key topics such as management of vertigo; management of adult sensorineural hearing loss; reflux in sinusitis; balloon catheter dilation in rhinology; epistaxis; functional rhinoplasty; sublingual immunotherapy for allergic rhinitis; pediatric obstructive sleep apnea; pediatric tonsillectomy; evaluation and management of unilateral vocal fold paralysis; management of hoarseness; endoscopic skull base resection for malignancy; management of glottic cancer; management of well-differentiated thyroid cancer; and management of the clinical node-negative neck in early stage oral cavity squamous cell carcinoma. Consolidates today’s available information and experience in this challenging area into one convenient resource.

Case studies, personal accounts, and analysis show how to recognize and combat pseudoscience in a post-truth world. In a post-truth, fake news world, we are particularly susceptible to the claims of pseudoscience. When emotions and opinions are more widely disseminated than scientific findings, and self-proclaimed experts get their expertise from Google, how can the average person distinguish real science from fake? This book examines pseudoscience from a variety of perspectives, through case studies, analysis, and personal accounts that show how to recognize pseudoscience, why it is so widely accepted, and how to advocate for real science. Contributors examine the basics of pseudoscience, including issues of cognitive bias; the costs of pseudoscience, with accounts of naturopathy and logical fallacies in the anti-vaccination movement; perceptions of scientific soundness; the mainstream presence of “integrative medicine,” hypnosis, and parapsychology; and the use of case studies and new media in science advocacy. Contributors David Ball, Paul Joseph Barnett, Jeffrey Beall, Mark Benisz, Fernando Blanco, Ron Dumont, Stacy Ellenberg, Kevin M. Folta, Christopher French, Ashwin Gautam, Dennis M. Gorman, David H. Gorski, David K. Hecht, Britt Marie Hermes, Clyde F. Herreid, Jonathan Howard, Seth C. Kalichman, Leif Edward Ottesen Kennair, Arnold Kozak, Scott O. Lilienfeld, Emilio Lobato, Steven Lynn, Adam Marcus, Helena Matute, Ivan Oransky, Chad Orzel, Dorit Reiss, Ellen Beate Hansen Sandseter, Kavin Senapathy, Dean Keith Simonton, Indre Viskontas, John O. Willis, Corrine Zimmerman

What is ‘good care’ and does more choice lead to better care? This innovative and compelling work investigates good care and argues that the often touted ideal of ‘patient choice’ will not improve healthcare in the ways hoped for by its advocates.

Taking a critical view, Homeopathy: An Illusion of Effectiveness is a treasure trove of information regarding the homeopathic system of medicine, reasoning through various unanswered questions concerning its principles and the scientific basis of its remedies. This book posits that the principles of homeopathy are inaccurate and homeopathic drugs have no therapeutic utility. Features: • Includes studies, observations, analysis, and conclusions of Dr. Samuel Hahnemann, the founder of homeopathy • Proves that principles of homeopathy are scientifically baseless and homeopathic drugs have no therapeutic effect • Provides a platform for creative and rational thinking • Promotes evidence-based medicine This book is the only one of its kind, explaining how Hahnemann framed the laws of this therapeutic system inaccurately due to lack of knowledge. At present, homeopathy is misleading the public and increasing morbidity and mortality because it is interfering with the application of modern medical science. This book will be useful in the medical community as well as the non-medical community, dispelling several myths associated with homeopathy by developing a rational approach based on scientific facts.