The Mysterious Epigenome

In this creative and inventive treatment, authors Thomas E. Woodward and James P. Gills take readers on an exploration of the human epigenome. Acting as tour guides leading visitors through a 3-D model of a human cell, Woodward and Gills bring to life the human molecular makeup. Readers (as visitors) will get up close and personal with the minute details of human molecular structure, including E. coli, flagellum, a DNA helix, an RNA molecule, and more. By seeing it with their own eyes, readers will gain a better understanding of their genetic systems and a better appreciation for the Creator who put this all into place.

Time to worry again—our lifestyle choices do impact our genetic code and that of our children (and even grandchildren!). "The potential is staggering. . . . The age of epigenetics has arrived."—Time, January 2010 Epigenetic means "on the gene," and the term refers to the recent discovery that stress in the environment can impact an individual's physiology so deeply that those biological scars are actually inherited by the next several generations. For instance, a recent study has shown that men who started smoking before puberty caused their sons to have significantly higher rates of obesity. And obesity is just the tip of the iceberg—many researchers believe that epigenetics holds the key to understanding cancer, Alzheimer's, schizophrenia, autism, and diabetes. Epigenetics is the first book for general readers on this fascinating and important topic. The book is driven by stories such as the Dutch famine of World War II, José Canseco and steroids, the breeding of mules and hinnies, Tazmanian devils and contagious cancer, and more.

From one of the country's foremost doctors comes a ground-breaking book about diagnosing, treating and healing Lyme, and peeling away the layers that lead to chronic disease. You may not know that you have Lyme. It can mimic every disease process including Chronic Fatigue Syndrome, Fibromyalgia, autoimmune conditions like MS, psychiatric conditions like depression and anxiety, and cause significant memory and concentration problems, mimicking early dementia. It is called the "Great Imitator," and inaccurate testing-combined with a fierce, ongoing debate that questions chronic infection-makes it difficult for sufferers to find effective care. When Dr. Richard Horowitz moved to the Hudson Valley over two decades ago to start his own medical practice, he had no idea that he was jumping into a hotbed of Lyme disease. He would soon realize that many of the chronic disease diagnoses people were receiving were also the result of Lyme-and he would discover how once-treatable infections, in the absence of timely intervention, could cause disabling conditions. In a field where the number of cases is growing exponentially around the world and answers remain elusive, Dr. Horowitz has treated over 12,000 patients and made extraordinary progress. His plan represents a crucial paradigm shift, without which the suffering will continue. In this book, Dr. Horowitz: - Breaks new ground with a 16 Point Differential Diagnostic Map, the basis for his revolutionary Lyme treatment plan, and an overarching approach to treating all chronic illness. - Introduces MSIDS, or Multiple Systemic Infectious Disease Syndrome, a new lens on chronic illness that may prove to be an important missing link. - Covers in detail Lyme's leading symptoms and co-infections, including immune dysfunction, sleep disorders, chronic pain and neurodegenerative disorders - providing a unique functional and integrative health care model, based on the most up-to-date scientific research, for physicians and health care providers to effectively treat Lyme and other chronic illnesses. Cutting through the frustration, misinformation and endless questions, Dr. Horowitz's enlightening story of medical discovery, science and politics is an all-in-one source for patients of chronic illness to identify their own symptoms and work with their doctors for the best possible treatment outcome.

Have you ever wondered... Why do people have to suffer? Did the Garden of Eden really exist? Is there evidence of design in the universe? Why is there so much sin and evil in the world? Was there really a worldwide flood in Noahs day? Do non-physical, supernatural entities actually exist? Were Adam and Eve a unique, divinely created couple? Who was Cains wife, and who did he fear would kill him? What is the age of the earth, thousands or billions of years? Was the tree of the knowledge of good and evil really a tree? Can evolution account for the diversity of life on earth today?

Introduces the new field that may revolutionize the understanding of human health and disease.

Why do we grow up to look, act, and feel as we do? Through most of the twentieth century, scientists and laypeople answered this question by referring to two factors alone: our experiences and our genes. But recent discoveries about how genes work have revealed a new way to understand the developmental origins of our characteristics. These discoveries have emerged from the new science of behavioral epigenetics--and just as the whole world has now heard of DNA, "epigenetics" will be a household word in the near future. Behavioral epigenetics is important because it explains how our experiences get under our skin and influence the activity of our genes. Because of breakthroughs in this field, we now know that the genes we're born with don't determine if we'll end up easily stressed, likely to fall ill with cancer, or possessed of a powerful intellect. Instead, what matters is what our genes do. And because research in behavioral epigenetics has shown that our experiences influence how our genes function, this work has changed how scientists think about nature, nurture, and human development. Diets, environmental toxins, parenting styles, and other environmental factors all influence genetic activity through epigenetic mechanisms; this discovery has the potential to alter how doctors treat diseases, and to change how mental health professionals treat conditions from schizophrenia to post-traumatic stress disorder. These advances could also force a reworking of the theory of evolution that dominated twentieth-century biology, and even change how we think about human nature itself. In spite of the importance of this research, behavioral epigenetics is still relatively unknown to non-biologists. The Developing Genome is an introduction to this exciting new discipline; it will allow readers without a background in biology to learn about this work and its revolutionary implications.

This is the first book that describes the role of the Epigenome (cytosine methylation) in the interplay between nature and nurture. It focuses and stimulates interest in what will be one of the most exciting areas of post-sequencing genome science: the relationship between genetics and the environment. Written by the most reputable authors in the field, this book is essential reading for researchers interested in the science arising from the human genome sequence and its implications on health care, industry and society.

Problems in Epistemology and Metaphysics takes a pro and con approach to two central philosophical topics. Each chapter begins with a question: Can We Have Knowledge? How are Beliefs Justified? What is the mind? Contemporary philosophers with opposing viewpoints are then paired together to argue their position and raise problems with conflicting standpoints. Alongside an up-to-date introduction to a core philosophical stance, each contributor provides a critical response to their opponent and clear explanation of their view. Discussion questions are included at the end of each chapter to guide further discussion. With chapters covering core questions surrounding religious beliefs, scientific knowledge, truth, being and reality, this is a comprehensive introduction to debates lying at the heart of what we know, how we know it and the nature of the world we live in.