The Newborn Lung

Dr. Richard Polin’s Neonatology Questions and Controversies series highlights the most challenging aspects of neonatal care, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today’s practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient. Stay fully up to date in this fast-changing field with The Newborn Lung, 3rd Edition. The most current clinical information throughout, including key management strategies that may reduce some of the chronic sequelae of neonatal respiratory failure. New content on the role of microbiome in lung injury and lung development. Current coverage of non-invasive respiratory support, perinatal events and their influence on lung development and injury, cell-based lung therapy, automation of respiratory support, and oxygenation targeting in preterm infants. Consistent chapter organization to help you find information quickly and easily. The most authoritative advice available from world-class neonatologists who share their knowledge of new trends and developments in neonatal care. Purchase each volume individually, or get the entire 7-volume set! Gastroenterology and Nutrition Hematology, Immunology and Genetics Hemodynamics and Cardiology Infectious Disease and Pharmacology New Volume! Nephrology and Fluid/Electrolyte Physiology Neurology The Newborn Lung

So much of our lung health throughout life is determined by what happens before birth and when we are born. Managing respiratory problems in newborn infants requires experience and teamwork, an understanding of the background to the problems, and knowledge of the evidence behind the clinical options available. In this Monograph, science, evidence and expertise are brought together in a collection of comprehensive, state-of-the-art reviews that cover: the structure and function of the newborn respiratory system; neonatal lung disease in preterm infants; developmental, structural and functional diseases of the respiratory system; and more. This book will prove a valuable resource for neonatal clinicians, scientists researching the area and adult clinicians managing lung health.

We have all been hypoxic. Fetal tolerance for intrauterine hypoxia arises from evolutionarily conserved physiological mechanisms, the antecedents of which can be learned from diving mammals or species at high altitudes. Understanding fetal hypoxia leads to understanding the huge physiological shifts of neonatal transition and the dangers of perinatal hypoxia. This comprehensive volume of topical review articles by expert authors addresses the origins of hypoxia tolerance, the impact of oxygen on circulatory transition at birth, and the biochemistry of hypoxia in the pulmonary circuit, as well as the classification, diagnosis, and clinical management of hypoxic respiratory failure and persistent pulmonary hypertension in the term neonate. The goal of Hypoxic Respiratory Failure in the Newborn is to connect our understanding of hypoxia from animals in extreme environments, with how the human fetus handles its hypoxic environment; and why the human newborn suddenly cannot. The book will educate health care professionals on how to care for newborns with hypoxic respiratory failure, including the use of up-to-date diagnostic tools and therapies. It also highlights areas of controversy and ongoing research in hypoxic respiratory failure and pulmonary hypertension of the newborn, including challenging case studies. Key Features Explores evolutionary context and comparative physiology of hypoxia tolerance in the fetus and neonate, from basic research to clinical scenarios Provides guidance to trainees, physicians, and allied health professionals engaged in NICU care; pediatricians, cardiologists, pulmonologists, anesthesiologists, neonatologists, and physiologists to effectively manage infants in hypoxic respiratory failure Includes case scenarios emphasizing current diagnostic and therapeutic controversies and algorithmic approaches to decipher difficult clinical cases

This exciting new reference brings you information about the most controversial pulmonary challenges you face in your practice. The book confidently tackles these subjects and gives seasoned advice on the latest diagnostic and treatment strategies using evidence-based medicine wherever possible. It gives you the latest information you need to keep pace with the fast-paced, dynamic environment of neonatology. Addresses controversial topics head on, so you can decide how to handle these difficult practice issues. Serves as the bridge between the latest cutting-edge research and its application to clinical practice. Assembles a world-class group of neonatologists, representing the true leaders of the specialty, to ensure the most authoritative content available.

The Newborn Lung, a volume in Dr. Polin's Neonatology: Questions and Controversies Series, offers expert authority on the toughest challenges in neonatal pulmonology and respiratory care. This medical reference book will help you provide better evidence-based care and improve patient outcomes with research on the latest advances. Reconsider how you handle difficult practice issues with coverage that address these topics head on, offering opinions from the leading experts in the field, supported by the best available evidence. Find information quickly and easily with a consistent chapter organization. Get the most authoritative advice available from world-class neonatologists who have the inside track on new trends and developments in neonatal care. Purchase each volume individually, or get the entire 6-volume set, which includes online access that allows you to search across all titles! Stay current in practice with in-depth coverage of presentation, pathogenesis, epidemiology, and prevention of bronchopulmonary dysplasia; short and long-term outcomes of oxygenation strategies in preterm infants; and many other hot topics in neonatal respiratory care. Access the fully searchable text online at www.expertconsult.com.

This book presents lung ultrasound as an accurate, reliable, low-cost and simple imaging technique, which poses no risk of radiation damage, making bedside use both feasible and convenient in neonatal wards. The aim of this book is to introduce the features of common lung diseases found in newborns that are detected using ultrasonic imaging. It introduces five important diseases, including respiratory distress syndrome (RDS), transient tachypnea of the newborn (TTN), infectious pneumonia of the newborn (IPN), pulmonary atelectasis of the newborn (PAN) and pneumothorax. In addition, the fundamental principles, commonly used terminologies and methods of performing lung ultrasound are also included in this book. The audience includes all neonatologists, pediatricians and pulmonologists.

Lung disease is a major indication for the admittance of the neonate to a specialist intensive care unit, and is a particularly common complication in the pre-term baby where the lungs are insufficiently developed at birth and easily damaged by early treatments. As a consequence, this is an area of intensive international research activity. In this comprehensive update of the well-received first edition, leading researchers from all over the world have been invited to contribute in their specialist areas. The book continues to provide detailed coverage of the pathogenesis, clinical and laboratory features and management of lung disorders in the neonate, with increased emphasis on the underlying immunology and major additions to the sections on respiratory support, chronic lung disease and abnormalities in lung growth and development to reflect the changes that have occurred in these areas since the previous edition appeared in 1995. Providing an unrivalled up-to-date statement on the problems that are faced in the neonatal intensive care unit on a daily basis, this is an invaluable addition to the bookshelves of neonatologists and other personnel involved in the care of critically ill babies.

Lung disease affects more than 600 million people worldwide. While some of these lung diseases have an obvious developmental component, there is growing appreciation that processes and pathways critical for normal lung development are also important for postnatal tissue homeostasis and are dysregulated in lung disease. This book provides an authoritative review of fetal and neonatal lung development and is designed to provide a diverse group of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease. The book covers genetics, omics, and systems biology as well as new imaging techniques that are transforming studies of lung development. The reader will learn where the field of lung development has been, where it is presently, and where it is going in order to improve outcomes for patients with common and rare lung diseases.