The Pathogenesis Of Bluetongue Virus Induced Vascular Dysfunction And Injury

The third volume in the Institute of Animal Health (IAH) Biology of Animal Infections Series, Bluetongue discusses one of the most economically important diseases of domesticated livestock. Affecting primarily sheep particularly the improved mutton and wool breeds, it is now endemic in Africa, India, the Middle and Far East, Australia and the Americas, and over the last six years has caused a series of outbreaks throughout the Mediterranean region and central Europe. Bluetongue represent a paradigm not only for the other orbiviruses (such as African horse sickness virus, which shares the same vector species) but also for other insect transmitted diseases, including those of humans. The only single definitive work that provides both historical and up to date data on the disease Describes the latest developments in epidemiological modelling, molecular epidemiology and vaccine development, as well as explaining the current global epidemiology of the disease Outlines the importance and possible mechanisms of overwintering, and the impact of global warming on the vectors and virus distribution

Bluetongue viruses (BTV) cause diseases that have serious economic consequences in ruminants (sheep, cattle) in many parts of the world. The incidence of bluetongue disease affects the international movement of animals and germ plasm. Although the etiological agent of the disease was isolated in 1900 and preliminary biochemical characterizations were pub lished as early as in 1969, most of the current understanding of the molecular biology, biochemistry, and genetics of BTV has evolved only recently. Triggered by the modern techniques of molecular biology, genetics, and immunology, BTV research has experienced an information explosion in the past 10 years. However, much of this information is scattered throughout an extensive literature. It is therefore an appropriate time to meld this together into a reference book. This book includes compre hensive information on BTV research provided in articles contributed by researchers from around the world. It covers what is known about the molecular structure of the virus and the current understanding of its biology, evolution, and relationships with its invertebrate and vertebrate hosts (infection, immunity, and pathogenicity).

Orbivirus: Advances in Research and Treatment: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Orbivirus in a compact format. The editors have built Orbivirus: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Orbivirus in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Orbivirus: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

With over 2,000 full-color illustrations, Pathologic Basis of Veterinary Disease, 5th Edition provides complete coverage of both general pathology and pathology of organ systems in one convenient resource. In-depth explanations cover the responses of cells, tissues, and organs to injury and infection. Expert researchers James F. Zachary and M. Donald McGavin keep you up to date with the latest advances in cellular and molecular pathology plus expanded coverage of genetics and disease, incorporating the newest insights into the study of disease mechanisms, genesis, and progression. Already the leading reference for pathology, this edition also includes an enhanced website with images of less common diseases and and guidelines for performing a complete, systematic necropsy. Each chapter is consistently organized, presenting information on structure, function, portals of entry, defense mechanisms, responses to injury, and diseases organized by species.Full-color illustrations, schematics, flow charts, and diagrammatic representations of disease processes make it easier to understand difficult concepts.Discussions of pathologic processes and individual disorders are integrated with the latest established information available.Clear, up-to-date explanations of disease mechanisms describe the cell, tissue, and organ response to injury and infection.Over 20 recognized experts deliver the most relevant information, whether you're a practitioner, student, or preparing for the American College of Veterinary Pathology board examination. Updated content on cellular and organ system pathology provides the latest on the science of inflammation, cellular injury, molecular carcinogenesis, and pathogenesis.NEW topics include the genetic basis of disease, the monocyte-macrophage system, diseases of the ear, and disorders of ligaments and joints and of the peritoneum.NEW coverage of World Organization for Animal Health (OIE) reportable diseases ("foreign animal diseases") adds information on microorganisms that have catastrophic impact on livestock health and production.NEW Mechanisms of Microbial Infections chapter adds in-depth coverage of the means by which microbes encounter, colonize, and cause disease in animals in a chronological sequence of events.NEW and updated flow charts, schematic illustrations, and diagrams of disease processes summarize important information and clarify complex concepts. An enhanced companion website includes all the images from the book, plus additional images and schematic illustrations of common diseases; guidelines for performing a complete, systematic necropsy and appropriate sample acquisition for selected organ systems; and a glossary of terms to accompany selected organ systems.

With over 2,000 full-color illustrations, Pathologic Basis of Veterinary Disease, 5th Edition provides complete coverage of both general pathology and pathology of organ systems in one convenient resource. In-depth explanations cover the responses of cells, tissues, and organs to injury and infection. Expert researchers James F. Zachary and M. Donald McGavin keep you up to date with the latest advances in cellular and molecular pathology plus expanded coverage of genetics and disease, incorporating the newest insights into the study of disease mechanisms, genesis, and progression. Already the leading reference for pathology, this edition also includes an enhanced website with images of less common diseases and and guidelines for performing a complete, systematic necropsy. Each chapter is consistently organized, presenting information on structure, function, portals of entry, defense mechanisms, responses to injury, and diseases organized by species. Full-color illustrations, schematics, flow charts, and diagrammatic representations of disease processes make it easier to understand difficult concepts. Discussions of pathologic processes and individual disorders are integrated with the latest established information available. Clear, up-to-date explanations of disease mechanisms describe the cell, tissue, and organ response to injury and infection. Over 20 recognized experts deliver the most relevant information, whether you're a practitioner, student, or preparing for the American College of Veterinary Pathology board examination. Updated content on cellular and organ system pathology provides the latest on the science of inflammation, cellular injury, molecular carcinogenesis, and pathogenesis. NEW topics include the genetic basis of disease, the monocyte-macrophage system, diseases of the ear, and disorders of ligaments and joints and of the peritoneum. NEW coverage of World Organization for Animal Health (OIE) reportable diseases ("foreign animal diseases") adds information on microorganisms that have catastrophic impact on livestock health and production. NEW Mechanisms of Microbial Infections chapter adds in-depth coverage of the means by which microbes encounter, colonize, and cause disease in animals in a chronological sequence of events. NEW and updated flow charts, schematic illustrations, and diagrams of disease processes summarize important information and clarify complex concepts. An enhanced companion website includes all the images from the book, plus additional images and schematic illustrations of common diseases; guidelines for performing a complete, systematic necropsy and appropriate sample acquisition for selected organ systems; and a glossary of terms to accompany selected organ systems.

With an emphasis on the disease conditions of dogs, cats, horses, swine, cattle and small ruminants, Jubb, Kennedy, and Palmer's Pathology of Domestic Animals, 6th Edition continues its long tradition of being the most comprehensive reference book on common domestic mammal pathology. Using a body systems approach, veterinary pathology experts provide overviews of general system characteristics, reactions to insult, and disease conditions that are broken down by type of infectious or toxic insult affecting the anatomical subdivisions of each body system. The sixth edition now boasts a new full-color design, including more than 2,000 high-resolution images of normal and abnormal organs, tissues, and cells. Updated content also includes evolved coverage of disease agents such as the Schmallenberg virus, porcine epidemic diarrhea virus, and the porcine deltacoronavirus; plus new information on molecular-based testing, including polymerase chain reaction (PCR) and in-situ hybridization, keep you abreast of the latest diagnostic capabilities. Updated content includes new and evolving pathogens and diagnostic techniques. Updated bibliographies give readers new entry points into the rapidly expanding literature on each subject. NEW! High-resolution color images clearly depict the diagnostic features of hundreds of conditions. NEW! Introduction to the Diagnostic Process chapter illustrates the whole animal perspective and details the approaches to systemic, multi-system, and polymicrobial disease. NEW! Coverage of camelids is now included in the reference’s widened scope of species. NEW! Team of 30+ expert contributors offers the latest perspective on the continuum of issues in veterinary pathology. NEW! Expanded resources on the companion website include a variety of helpful tools such as full reference lists with entries linked to abstracts in Pub Med and bonus web-only figures. NEW! Full-color design improves the accessibility of the text.