The Peptides Major Methods Of Peptide And Bond Formation
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Major Methods of Peptide Bond Formation
Author | : Erhard Gross,Johannes Meienhofer |
Publsiher | : Elsevier |
Total Pages | : 454 |
Release | : 2014-05-10 |
Genre | : Science |
ISBN | : 9781483217963 |
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The Peptides: Analysis, Synthesis, Biology, Volume 1: Major Methods of Peptide Bond Formation provides comprehensive and critical reviews of important developments in three major areas of peptide research—analysis, synthesis, and biology. This book discusses the nature of the peptide bond, coupling between amino acid residues, and catalysis of active ester reactions. The formation of hydrazides, reactions of carbodiimides with amines, and mixed carbonic anhydride method of peptide synthesis are also elaborated. This publication likewise covers the control of racemization during peptide synthesis, strategies for minimizing racemization during amide-forming steps, and assays for chiral purity. This volume is suitable for students, specialists, and scientists from a broad range of disciplines concerned with peptides.
Special Methods in Peptide Synthesis
Author | : Erhard Gross |
Publsiher | : Unknown |
Total Pages | : 554 |
Release | : 1983 |
Genre | : Peptides |
ISBN | : 0123042054 |
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The Peptides Major methods of peptide and bond formation
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Author | : Erhard Gross,Johannes Meienhofer |
Publsiher | : Unknown |
Total Pages | : 135 |
Release | : 1979 |
Genre | : Peptides |
ISBN | : LCCN:78031958 |
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The Peptides
Author | : Eberhard Schröder,Klaus Lübke |
Publsiher | : Elsevier |
Total Pages | : 512 |
Release | : 2014-05-12 |
Genre | : Science |
ISBN | : 9781483261720 |
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The Peptides, Volume I: Methods of Peptide Synthesis focuses on detailed description of protecting groups, individual amino acids, and coupling reactions. The publication first offers information on amino-protecting and carboxyl-protecting groups, including carboxyl protection by salt formation, esterification, and amide formation and acyl-type, alkyl-type, and urethane protecting groups. The text then examines the formation of the peptide bond and amino acids. Discussions focus on amino acids with the alcoholic hydroxyl group, sulfur amino acids, basic and acidic amino acids, synthesis of peptides by activation of the amino group, and peptide synthesis by activation of the carboxyl group. The manuscript elaborates on the synthesis of cyclic peptides, depsipeptides, peptoids, and the plastein reaction. Topics include synthesis of plastein-active peptides, glycopeptides, phosphopeptides, and S-peptides. The publication is a dependable source of data for readers interested in the methods of peptide synthesis.
Chemical Approaches to the Synthesis of Peptides and Proteins
Author | : Paul Lloyd-Williams,Fernando Albericio,Ernest Giralt |
Publsiher | : CRC Press |
Total Pages | : 306 |
Release | : 2020-08-18 |
Genre | : Cooking |
ISBN | : 9781000151688 |
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Organic chemists working on the synthesis of natural products have long found a special challenge in the preparation of peptides and proteins. However, more reliable, more efficient synthetic preparation methods have been developed in recent years. This reference evaluates the most important synthesis methods available today, and also considers methods that show promise for future applications. This text describes the state of the art in efficient synthetic methods for the synthesis of both natural and artificial large peptide and protein molecules. Subjects include an introduction to basic topics, linear solid-phase synthesis of peptides, peptide synthesis in solution, convergent solid-phase synthesis, methods for the synthesis of branched peptides, formation of disulfide bridges, and more. The book emphasizes strategies and tactics that must be considered for the successful synthesis of peptides.
The Chemical Synthesis of Peptides
Author | : John Jones |
Publsiher | : Oxford University Press, USA |
Total Pages | : 248 |
Release | : 1991 |
Genre | : Language Arts & Disciplines |
ISBN | : UOM:39015031709291 |
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This book focuses on the chemical principles behind the more important methods of peptide synthesis, and it provides a critical, concise, and up-to-date survey of the field.
Peptides
Author | : Bernd Gutte |
Publsiher | : Elsevier |
Total Pages | : 527 |
Release | : 1995-10-24 |
Genre | : Science |
ISBN | : 9780080538594 |
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In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology. Active research programs worldwide are now engaged in developing peptide-based drugs and vaccines using modification of natural peptides and proteins, design of artificial peptides and peptide mimetics, and screening of peptide and phage libraries. In this comprehensive book, the authors discuss peptide synthesis and application within the context of their increasing importance to the pharmaceutical industry. Peptides: Synthesis, Structures, and Applications explores the broad growth of information in modern peptide synthetic methods and the structure-activity relationships of synthetic polypeptides. The history of peptide chemistry Amide formation, deprotection, and disulfide formation in peptide synthesis Solid-phase peptide synthesis a-helix formation by peptides in water Stability and dynamics of peptide conformation An overview of structure-function studies of peptide hormones Neuropeptides:peptide and nonpeptide analogs Reversible inhibitors of serine proteinases Design of polypeptides Current capabilities and future possibilities of soluble chemical combinatorial libraries Epitope mapping with peptides Synthesis and applications of branched peptides in immunological methods and vaccines
The Peptides Special methods in peptide synthesis Pt A
Author | : Erhard Gross,Johannes Meienhofer |
Publsiher | : Unknown |
Total Pages | : 632 |
Release | : 1979 |
Genre | : Peptides |
ISBN | : STANFORD:36105003313025 |
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