Untangling Molecular Biodiversity Explaining Unity And Diversity Principles Of Organization With Molecular Structure And Evolutionary Genomics

Untangling Molecular Biodiversity presents a unique global framework to explain molecular and organismal biodiversity that is grounded in evolutionary genomics. This book will tackle important questions such as the origin of life, the emergence of biochemistry, the origin of viruses, the nature of the last universal common ancestor responsible for diversified life, the role of information and thermodynamics in evolution, the reason for having three cellular domains in life, and the centrality of modules in biology.This book will explore six themes: (1) Explanatory frameworks for biological organization; (2) Evolutionary patterns and biodiversity; (3) Molecular structure and evolutionary genomics; (4) A framework of persistence strategies that borrows from engineering and systems biology; (5) Use of this framework to explain diversity in the molecular world; and (6) Exploring the origin and evolution of cells and viruses.Consequently, this book represents a very unique collection of ideas that can attract the attention of a broad readership interested in life sciences/biology.

In this landmark work, the author team led by Dr. Sean Carroll presents the general principles of the genetic basis of morphological change through a synthesis of evolutionary biology with genetics and embryology. In this extensively revised second edition, the authors delve into the latest discoveries, incorporating new coverage of comparative genomics, molecular evolution of regulatory proteins and elements, and microevolution of animal development. An accessible text, focusing on the most well-known genes, developmental processes and taxa. Builds logically from developmental genetics and regulatory mechanisms to evolution at different genetic morphological levels. Adds major insights from recent genome studies, new evo-devo biology research findings, and a new chapter on models of variation and divergence among closely related species. Provides in-depth focus on key concepts through well-developed case studies. Features clear, 4-color illustrations and photographs, chapter summaries, references and a glossary. Presents the research of Dr. Carroll, a pioneer in the field and the past president of the Society for Developmental Biology.

This book is a unique introduction to the fields of macroevolution and macroecology, taking an enquiry-led approach to exploring the evolution and distribution of biodiversity across time, space and lineages.The only introduction to macroevolution and macroecology to adopt an innovative enquiry-led, case study-based framework to encourage active learning and critical thinking, this book:Extends the study of evolutionary biology and ecology beyond the topics covered in typical undergraduate textsExplores the nature of scientific investigation by emphasising hypothesis testing and highlighting the range of analytical tools available to contemporary researchersEncourages active student-driven learning by using open questions and current debates to promote critical thinking, identify interesting and important problems, and demonstrate how to frame testable research hypothesesCombines these three skills--an understanding of macroevolutionary and macroecological principles and patterns, a grasp of hypothesis testing, and the ability to identify important questions--to allow students to look at the world with new eyes, and develop an understanding of why the biological world is as it is.

Mark Chase There are many literature resources available to molecular biologists wishing to assess genetic variation, but the myriad of techniques and approaches potentially available to the plant breeder and the evolutionary biologist is truly bewildering, and most have never been evaluated side-by-side on the same sets of samples. Additionally, it is often not recognized that tools that are useful for breeders can often be adapted for use in evolutionary studies and vice versa, but this is generally the case. The borderline between population genetics and phylogenetics is vague and difficult to assess, and a combination of both types of tools is best when it is not clear with which area one is dealing. Furthermore, it is not now appropriate to use just one type of marker in any kind of study; most markers have the potential to misinform under certain conditions, so it is always wise to incorporate at least two different types of assessments into any project. This volume is designed to facilitate this sort of multiple approach and provides comparative data on most currently available methods so that researchers can more intelligently select those appropriate to their area of interest, regardless of whether it is in the realm of breeding or evolutionary biology.

Publisher Description

This book provides insight into the use of molecular and genomic techniques to the study of populations of critically important species at various geographical scales. It delves into a wide range of issues relevant to biodiversity conservation, such as population differentiation, landscape genomics, ecological interactions, phylogenetics, phylogeography, metagenomics, molecular methods, and data processing. The current rate of biodiversity loss is unprecedented and valuable genetic resources are being lost at an alarmingly rate. Effective strategies to conserve these genetic resources are essential to maintain healthy ecosystems with inter-dependent species. The book is an invaluable resource for training undergraduate and graduate students, postdoctoral fellows, and for young researchers. This book is particularly useful for the policy makers and academics who want to learn about important concepts in population and conservation genetics and genomics.

This book is a unique collection of evolutionary and ecological perspectives in the study of biodiversity by some of the leading researchers in the field. The seventeen chapters are divided into three sections, each section beginning with an overview of its contents. The book traces pastlandmarks, current questions, and future trends in biodiversity reseach ranging from the evaluation of the fossil record and molecular phylogenies in untangling the genesis of diversity; to population, community, and ecosystem-level approaches in understanding patterns of species persistence; andfinally to large-scale diversity patterns and species conservation. Subject reviews, case-studies, and discussions of techniques are combined to produce a state-of-the-art book.

Considerable attention is being paid to the use of molecular evidence in studies of human diversity and origins. Much of the early work was based on evidence from mitochondrial DNA, but this has been supplemented by important information from nuclear DNA from both the Y chromosomes and the autosomes. The bulk of the material available is also from living populations, but this is being extended by the study of DNA from archaic populations. The underlying models used in interpreting this evidence are developments of the neutral theory of molecular evolution, but also consider the possible role of selection. This 1996 volume brings together evidence from an international group of research workers. It will be an important reference for researchers in human biology, molecular biology and genetics alike.