Yeast Physiology And Biotechnology

Hefen sind die weltweit wichtigste industriell genutzte Klasse von Mikroorganismen. Viele Lehrbücher beschäftigen sich mit der Molekularbiologie und Genetik dieser Spezies; die Physiologie dagegen ist nur selten ein Thema. Das vorliegende Lehrbuch will diese Lücke füllen - Wachstum und Stoffwechsel der Hefezellen werden behandelt, und stets werden Verbindungen zur biotechnologischen Anwendung aufgezeigt. 06/98

Yeasts are eukaryotic and single-celled microorganisms that belong to the fungus kingdom. The beneficial physiological characteristics of yeasts have led to their application in the field of biotechnology. Sugar fermentation by yeast is the oldest and most widespread application of this technology. The production of different foods involve the use of different type of yeasts, including brewer's yeast for fermenting beer, baker's yeast for production of bread, as well as yeast for making xylitol and wine. They are also utilized as biocontrol agents in agriculture. They can also be used as a source of biocatalysts for the creation of protein medicines and high-value fine chemicals. This book is a valuable compilation of topics, ranging from the basic to the most complex advancements in the field of yeast biotechnology. It will help the readers in keeping pace with the rapid changes in these fields.

Biotechnology Biotechnology is is now now established established as as a a major major area area of of technology, technology, concerned concerned with with the' the' application application of of biological biological organisms, organisms, systems systems or or processes processes to to manufac turing turing or or service service industries'. industries'. Although Although the the exploitation exploitation of of organisms organisms by by man man is is not not new, new, many many of of the the techniques techniques which which are are stimulating stimulating the the rapid rapid advances advances in in biotechnology biotechnology have have developed developed from from recent recent scientific scientific discoveries. discoveries. Throughout Throughout history history man man has, has, knowingly knowingly or or not, not, been been exploiting exploiting yeast yeast in in the the production production of of alcoholic alcoholic beverages beverages and and bread, bread, and and these these processes processes still still represent represent major major biotechnological biotechnological industries. industries. The The brewer's brewer's and and baker's baker's yeast yeast Sac charomyces charomyces cerevisiae cerevisiae is, is, however, however, also also a a favoured favoured organism organism for for the the production production of of many many new new biotechnological biotechnological products. products.

Since the publication of the best-selling first edition, much has been discovered about Saccharomyces cerevisiae, the single-celled fungus commonly known as baker's yeast or brewer's yeast that is the basis for much of our understanding of the molecular and cellular biology of eukaryotes. This wealth of new research data demands our attention and r

This book discusses genome-based strategies to provide a holistic understanding of yeasts in Human Health and as model organisms in basic research or industrial production. Using numerous Saccharomyces cerevisiae strains and various non-conventional yeast species isolated from diverse origins, it describes essential biological processes, the biotechnological exploitation of yeast and pathogenesis control. It also demonstrates how functional and comparative genomics and the development of genome engineering tools are used in modern yeast research. The use of yeasts as experimental eukaryotic models increasingly gained prominence when several Nobel Prizes in Physiology/Medicine and Chemistry were awarded for innovative research, using yeast strains to elucidate molecular mechanisms in a wide range of human physiological processes and diseases, such as autophagy, cell cycle regulation and telomerase activity. This book offers useful insights for scientists in yeast research, clinical scientists working with yeast infectious models and for industrial researchers using applied microbiology.

This collection of review articles covering the molecular biology and biotechnology of yeasts is compiled from the interdisciplinary series of books entitled Biotechnology and Genetic Engineering Reviews.

This text emphasises the importance of staying informed about Saccharomyces cerevisiae as it provides the intellectual basis for much of the molecular and cellular biology of eukaryotes. It offers yeast users a concise account of the metabolism and physiology of this organism. Chapters include: life cycle and morphogenesis; carbon metabolism, nitrogen metabolism; lipids and membranes; protein trafficking; and phosphorlation and dephosphorylation of protein and stress response. This book is for second and final year undergraduates in microbiology, biotechnology and applied biology, postgraduate and doctural researchers working on yeast, and researchers and managers in industries which use and exploit Saccharomyces cerevisiae.

In recent years, new yeast species have proven their value and novel biotechnological applications have emerged. This book compiles the multi-faceted genetic repertoire of several yeasts relevant to modern biotechnology, and describes their utilization in research and application in the light of their genetic make-up and physiological characteristics. Moreover, the book presents a thorough overview of a wide array of methodologies from classical genetics to modern genomics technologies that have been and are being used in functional analysis of yeasts.