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In Fragile X-Associated Tremor Ataxia Syndrome (FXTAS), the editors present information on all aspects of FXTAS, including clinical features and current supportive management, radiological, psychological, and pathological findings, genotype-phenotype relationships, animal models and basic molecular mechanisms. Genetic counseling issues are also discussed. The book should serve as a resource for professionals in all fields regarding diagnosis, management, and counseling of patients with FXTAS and their families, as well as presenting the molecular basis for disease that may lead to the identification of new markers to predict disease risk and eventually lead to target treatments.

This text is designed for graduate-level courses in real analysis. Real Analysis, 4th Edition, covers the basic material that every graduate student should know in the classical theory of functions of a real variable, measure and integration theory, and some of the more important and elementary topics in general topology and normed linear space theory. This text assumes a general background in undergraduate mathematics and familiarity with the material covered in an undergraduate course on the fundamental concepts of analysis.

This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.

Wireless localization techniques are an area that has attracted interest from both industry and academia, with self-localization capability providing a highly desirable characteristic of wireless sensor networks. Localization Algorithms and Strategies for Wireless Sensor Networks encompasses the significant and fast growing area of wireless localization techniques. This book provides comprehensive and up-to-date coverage of topics and fundamental theories underpinning measurement techniques and localization algorithms. A useful compilation for academicians, researchers, and practitioners, this Premier Reference Source contains relevant references and the latest studies emerging out of the wireless sensor network field.

The Technical Paper addresses the issue of freshwater. Sealevel rise is dealt with only insofar as it can lead to impacts on freshwater in coastal areas and beyond. Climate, freshwater, biophysical and socio-economic systems are interconnected in complex ways. Hence, a change in any one of these can induce a change in any other. Freshwater-related issues are critical in determining key regional and sectoral vulnerabilities. Therefore, the relationship between climate change and freshwater resources is of primary concern to human society and also has implications for all living species. -- page vii.

English mathematician ISAAC BARROW (1630-1677), one of the inventors of calculus, had a profound impact on his student, Isaac Newton. Here, in this 1916 volume, British historian of mathematics JAMES MARK CHILD translates from the original Latin Barrow's masterpiece, Lectiones Opticae et Geometricae, his lectures on mathematics, demonstrating Barrow's essential role in the development of the higher math. Complete with Child's comprehensive introduction to Barrow's life and notes and discussion on his work, this new edition of an important but hard-to-find book will intrigue students of the history of science and math lovers alike,