Bio Orthopaedics

This book introduces the exciting field of orthobiology, which will usher in a new array of therapeutic approaches that stimulate the body’s natural resources to regenerate musculoskeletal tissues damaged by trauma or disease. The book addresses a range of key topics and discusses emerging approaches that promise to offer effective alternatives to traditional treatments for injuries to bone, cartilage, muscles, ligaments, and tendons. It explains in detail how a variety of innovative products, including biomaterials, growth factors, and autogenous cells, together provide the basis for the regeneration of these musculoskeletal structures and how recent scientific progress has created unique opportunities to address pathological situations that until recently have been treated with unsatisfactory results. The authors are experts from across the world who come together to provide a truly global overview. The book is published in collaboration with ISAKOS. It will be invaluable for all with an interest in this area of medicine, which has already attained huge popularity in Orthopaedics and Sports Medicine and has also attracted the attention of the lay public.

Now in its revised, updated Sixth Edition, this text provides residents and medical students with a broad overview of adult and pediatric orthopaedics. Major sections focus on general and regional disorders of the musculoskeletal system. This edition’s chapters on regional disorders have separate adult and pediatric sections and include sports medicine information and reviews of anatomy. Coverage of each disorder includes more details on treatment and prognosis. This edition also provides expanded coverage of molecular orthopaedics, biomaterials, orthotics and prosthetics, diagnosis by physical examination, commonly ordered laboratory tests, rehabilitation, biomechanics, principles of fractures, osteoporosis, overuse syndromes, and Achilles tendon rupture.

Human Orthopaedic Biomechanics: Fundamentals, Devices and Applications covers a wide range of biomechanical topics and fields, ranging from theoretical issues, mechanobiology, design of implants, joint biomechanics, regulatory issues and practical applications. The book teaches the fundamentals of physiological loading and constraint conditions at various parts of the musculoskeletal system. It is an ideal resource for teaching and education in courses on orthopedic biomechanics, and for engineering students engaged in these courses. In addition, all bioengineers who have an interest in orthopedic biomechanics will find this title useful as a reference, particularly early career researchers and industry professionals. Finally, any orthopedic surgeons looking to deepen their knowledge of biomechanical aspects will benefit from the accessible writing style in this title. Covers theoretical aspects (mechanics, stress analysis, constitutive laws for the various musculoskeletal tissues and mechanobiology) Presents components of different regulatory aspects, failure analysis, post-marketing and clinical trials Includes state-of-the-art methods used in orthopedic biomechanics and in designing orthopedic implants (experimental methods, finite element and rigid-body models, gait and fluoroscopic analysis, radiological measurements)

This user-friendly, pragmatic book discusses the normal and pathological conditions of the appendicular skeleton, with a focus on the preservation of joint function, providing a detailed overview of strategies for both common and complex joint preservation. The first section covers basic topics, ranging from joints homeostasis and biomechanics, to genetics, bio-orthopedics, tissue engineering and 3D bioprinting. The following sections are each dedicated to a specific joint – its functional anatomy, pathologic conditions, diagnostics and treatment. This book is of interest to orthopedists and sports medicine specialists treating common and complex injuries of the joints.

Biomaterials / Ahmed El-Ghannam and Paul Ducheyne -- Biomechanics of the spine / Ian A. F. Stokes and James C. Iatridis -- Biomechanics of fracture fixation and fracture healing / Lutz E. Claes and Keita Ito -- Biomechanics and preclinical testing of artificial joints: the hip / Rik Huiskes and Jan Stolk -- Biomechanics of total knee replacement designs / Peter S. Walker.

The first medical reference textbook to compile an unprecedented synthesis of evidence for regenerative orthopedics by key opinion leaders Thirty-five authors address your clinical questions What emerging technologies are right for my clinical practice? How can I strengthen my patients before their orthopedic surgery? Practically speaking, how can I leverage the latest metabolic therapies to safeguard my patients from toxins, medications, food and chronic diseases known to adversely affect the musculoskeletal system? "Ask the Author" feature Would you like to discuss a patient with a particular author? Now you can do so at www.betterorthopedics.com. First to be second Did you notice this book is the first book in regenerative orthopedics to publish a second edition? This diverse author team leads the growing field of regenerative orthopedics and offers the broadest and in-depth approach to leveraging metabolic therapies. This book comprises the professional opinion of its authors. It does not claim to represent guidelines, recommendations, or the current standard of medical care.

This book incorporates the experience of numerous experts who explore contemporary opinion of how best to rationalise and optimise the interfaces at total hip replacement to provide the most favourable and durable results. The survival of a total hip replacement depends principally on the enduring integrity of the fixation interfaces and of the articular interface. The design of the stem and the material properties of cement largely determine the state of the component-cement inter face, while the bone-cement interface is significantly influenced by both mechanical and biological factors. The surface finish and shape of cementless implants are designed to preserve the integrity of biological fixation (osseo-integration) at the bone-component interface. Once again, both mechanical and biological factors have to be considered, while bioactive coatings accelerate bone ongrowth. Metal-on-polyethylene is the most widely used articular interface. However, it has been suggested that wear of polyethylene is one of the major factors contributing to failure of total hip replacements. The increasing prevalence of total hip replacement in younger patients has stimulated the investigation of alternative, more durable couples -including ceramic-polyethylene, ceramic-ceramic and metal-on-metal. Modularity provides greater intra-operative flexibility, but each new modular interface introduces new mechanisms of failure. These need to be anticipated and appropriate measures taken to avoid them. Hopefully this book will provide a better understanding of the factors that contribute to stable interfaces and long-term survival of total hip arthroplasty.

Old age is increasingly becoming the focus of research and development in Europe. Concerning orthopaedics and sports medicine, the elderly especially are considered as frail patients who need support to maintain the health of their musculoskeletal systems. For this reason, several interventions regarding physical activity have been investigated in recent years in order to understand whether some programs of physical activity are better than others as conservative treatments for degenerative musculoskeletal pathologies (i.e., osteoarthritis, rotator cuff arthropathy, and lower back pain). Furthermore, several investigations have been carried out to understand the best preoperative and postoperative protocols of physical activity to improve the results of orthopaedic surgery. The aim of this Special Issue was to collect the updated evidence concerning these topics in the form of a collection of systematic reviews of the literature.